维普中文期刊产品整合服务
3篇 您的检索式:作者名="Markus Prinz"
    题名 作者 年代 出处 被引量
1Inhibition of T-Cell Proliferation by Helicobacter pylori γ-Glutamyl Transpeptidase显示文摘Christian Schmees Christian Prinz Tilman Treptau Roland Rad Ludger Hengst Petra Voland Stefan Bauer Lena Brenner Roland M. Schmid Markus Gerhard 2007Gastroenterology2007,,5:1
2Inhibition of T-Cell Proliferation by Helicobacter pylori γ-Glutamyl Transpeptidase显示文摘Christian Schmees Christian Prinz Tilman Treptau Roland Rad Ludger Hengst Petra Voland Stefan Bauer Lena Brenner Roland M. Schmid Markus Gerhard 2007Gastroenterology2007,,5:1
3Development and assessment of a cutaneous tissue stretch device as a novel scar therapy显示文摘Aim:Scar prevention and reduction is an area of therapeutic opportunity and unmet medical need.With no current effective scar therapy,patients are often disappointed in their appearance post surgery and re-present to surgeons,only to be turned away.The purpose of this study was to develop and test a device that produces intermittent parallel stretch on new scars and to analyze its potential to reduce scarring.Methods:Mice were randomized into 5 scar stretch treatment groups:1 control,1 sham,and 3 stretch models(0.5×,1×,or 2×device strength)and treated for 10 days.Scars were scored using the Vancouver Scar Scale.Scar tissue samples were compared by histology and transforming growth factor beta 1(TGF-β1)expression between control and treatment groups.Results:Scar scores of 0.5×and 1×groups were significantly lower than the control group(P<0.05).Scar scores from the 1×treatment group were also significantly lower than the 0.5×group(P<0.05).Sham,control scar and 2×groups showed more collagen deposition and a thicker dermal scar than the 0.5×and 1×groups.Unstretched scars had fewer fibroblasts with more collagen deposition than the 0.5×and 2×groups.TGF-β1 levels were significantly lower in the 0.5×(342.1±9.2)and 1×(254.1±3.1)groups than in the control group(P<0.05).TGF-β1 levels in the 1×treatment group were also significantly lower than the 0.5×treatment group(P<0.05).Conclusion:Intermittent cutaneous tissue stretch parallel to scars during the proliferative phase of wound healing decreases fibrosis on a macroscopic,microscopic and biochemical level.Jonathan Kanevsky Joshua Vorstenbosch Julian Diaz-Abele Tyler Safran Markus Prinz Youssef Tahiri Mirko Gilardino Satya Prakash 2016Plastic and Aesthetic Research2016,3,1:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费