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| 1 | 0Adipose-derived stem cells: Implications in tissue regeneration显示文摘Adipose-derived stem cells(ASCs) are mesenchymal stem cells(MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differ-entiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs dam-aged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration. | Wakako Tsuji J Peter Rubin Kacey G Marra | 2014 | World Journal of Stem Cells2014,6,3: | 19 |
| 2 | challenges of advanced hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is an aggressive malignancy,resulting as the third cause of death by cancer each year. The management of patients with HCC is complex,as both the tumour stage and any underlying liver disease must be considered conjointly. Although surveillance by imaging,clinical and biochemical parameters is routinely performed,a lot of patients suffering from cirrhosis have an advanced stage HCC at the first diagnosis. Advanced stage HCC includes heterogeneous groups of patients with different clinical condition and radiological features and sorafenib is the only approved treatment according to Barcelona Clinic Liver Cancer. Since the introduction of sorafenib in clinical practice,several phase Ⅲ clinical trials have failed to demonstrate any superiority over sorafenib in the frontline setting. Locoregional therapies have also been tested as first line treatment,but their role in advanced HCC is still matter of debate. No single agent or combination therapies have been shown to impact outcomes after sorafenib failure. Therefore this review will focus on the range of experimental therapeutics for patients with advanced HCC and highlights the successes and failures of these treatments as well as areas for future development. Specifics such as dose limiting toxicity and safety profile in patients with liver dysfunction related to the underlying chronic liver disease should be considered when developing therapies in HCC. Finally,robust validated and reproducible surrogate end-points as well as predictive biomarkers should be defined in future randomized trials. | Stefano Colagrande Andrea L Inghilesi Sami Aburas Gian G Taliani Cosimo Nardi Fabio Marra | 2016 | World Journal of Gastroenterology2016,22,34: | 19 |
| 3 | Fluoroquinolone-macrolide combination therapy for chronic bacterial prostatitis: retrospective analysis of pathogen eradication rates, inflammatory findings and sexual dysfunction显示文摘我们以前在范畴 II 长期的细菌的前列腺炎(CBP ) 表明了 fluoroquinolone-macrolide 联合治疗的安全和功效。这研究的目的是回顾地基于 azithromycin 的联合为 CBP 比较 microbiological 和二个处理计划的临床的调查结果(500 mg,三次每周) 与一次每日的 500-mg 或 ciprofloxacin 的 750-mg 剂量(Cipro-500 或 Cipro-750 队,分别地) 。azithromycin 的联合管理(1500 有以 750 的率的 ciprofloxacin 的 mg 星期 −1) ;为 4 个星期而非在 500 的 mg 天 −1 ;为 6 个星期的 mg 天 −1 从 62.35 % 增加了根除率;到 77.32 %并且从 71.76 % 的全部的细菌学的成功;到 85.57 %。在煽动性的白血球计数和浆液的疼痛和 voiding 症状 / 症状和重要减小地的重要减少前列腺特定的抗原(PSA ) 在两个组在整个 18 月的后续经期被支撑。射精的疼痛, haemospermia 和早泄显著地在两个组在 microbiological 根除上被稀释,但是后者在 Cipro-750 队更即时减退了。总共, 59 个 Cipro-750 病人显示出 mild-to-severe 在基线的可勃起的机能障碍(编辑) ,当 22 个病人没在 microbiological 根除上并且在整个后续时期有编辑时。在结论 fluoroquinolone-macrolide,治疗在病原体根除和 CBP 症状变细导致了,包括疼痛, voiding 骚乱和性机能障碍。为 4 个星期的 ciprofloxacin 的一次每日的 750-mg 剂量与 500-mg 剂量相比显示出提高的根除率和更低的煽动性的白血房间计数 6 个星期。我们的结果是开的推进未来的确认。 | Vittorio Magri Emanuele Montanari Visnja Skerk Alemka Markotic Emanuela Marras Antonella Restelli Kurt G Naber Gianpaolo Perletti | 2011 | Asian Journal of Andrology2011,13,6: | 12 |
| 4 | 显示文摘 | Meda L Marra G | 2005 | Composites Science and Technology2005,65,5: | 1 |
| 5 | Radio frequency treatment of foods: Review of recent advances 显示文摘 | Marra F Zhang L Lyng J G | 2009 | Journal of Food Engineering2009,91,: | 1 |
| 6 | Numerical simulation of turbulent gas flames in tubes显示文摘 | Salzano E Marra F S Russo G | 2002 | Journal of Haz- ardous Materials2002,95,3: | 1 |
| 7 | Waters, national occupational research agenda (NORA) future directions in occupational musculoskeletal disorder health research 显示文摘 | William S Marras Robert G Cutlip Susan E Burt | 2009 | AppliedErgonomics2009,40,: | 1 |
| 8 | Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epi-phe- nomenon显示文摘 | Targher G Marra F Marchesini G | 2008 | Diabetologia2008,51,11: | 1 |
| 9 | A new efficient resveratr ol synthesis显示文摘 | MARCELLA G O MARRA C O ANGELA F | 2002 | Tetrahedron Letters2002,,43: | 1 |
| 10 | Relation between depression after stroke, antidepressant therapy, and functional recovery显示文摘 | Gainotti G Antonucci G Marra C | 2001 | J Neurol Neurosurg Psychiatry2001,71,2: | 1 |
| 11 | Radio frequency treatment of foods: Review of recent advances 显示文摘 | Marra F Zhang L Lyng J G | 2009 | Journal of Food Engineering2009,91,: | 1 |
| 12 | Relation between de- pression after stroke, antidepressant therapy, and functional re- covery 显示文摘 | Gainotti G Antonucci G Marra C | 2001 | J Neurol Neurosurg Psychiatry2001,71,2: | 1 |
| 13 | Gated SPECT evaluation of left ventricular function using a CZT camera and a fast low- dose clinical protocol:compatison to cardiac magnetic resonance imaging显示文摘 | Giorgetti A Masci PG Marras G | 2013 | Eur J Nucl Med Mol Imaging2013,40,12: | 1 |
| 14 | Increased risk of cardiovascular diseasein non-alcoholic fatty liver disease: causal effect or epiphenomenon显示文摘 | Targher G Marra F Marchesini G | 2008 | Diabetologia2008,51,: | 1 |
| 15 | Intrathecal baclofen therapy in patients with severe spasticity显示文摘 | Marra G A Aleo G Di Bella P | 2007 | Aeta Neuroehir Suppl2007,97,1: | 1 |
| 16 | Nano-aluminum as energetic material for rocket propellants显示文摘 | Meda L Marra G Galfetti L | 2007 | Mate- rials Science and Engineering C2007,27,5: | 1 |
| 17 | Relationship between particle size distribution and compressive strength in Portland cement 显示文摘 | Frigioine G Marra S | 1976 | Cement and Concrete Research1976,6,1: | 1 |
| 18 | Early increase of oxidative stress and reduced antioxidant defenses in patients with uncomplicated type 1 diabetes: a case for gender difference显示文摘 | Marra G Cotroneo P Pitocco D | 2002 | Diabetes Care2002,25,2: | 1 |
| 19 | Variation of tension in the long head of the biceps tendon as a function of limb position with simulated biceps contraction显示文摘 | Gramstad G Sears B Marra G | 2010 | Inter J Shoulder Surg2010,4,1: | 1 |
| 20 | Increased risk of cardiovascular disease in non - alcoholic fatty liver disease : causal effect or epiphe-nomenon? 显示文摘 | Targher G Marra F Marchesini G | 2008 | Diabetologia2008,51,11: | 1 |