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| 1 | 腐植酸对黄瓜植株生长的影响涉及与硝酸盐浓度有关的细胞分裂素、多胺、矿质营养素浓度在植株根系和芽中的变化显示文摘许多研究报道腐植酸类物质能够促进不同环境下的幼苗栽培物的生长。然而对腐植酸促进植物生长的作用机理,科学工作者却知之甚少。腐植酸类物质对植物幼苗的影响涉及根质膜H+-ATP酶活性及根系和芽中硝酸根分布的主要作用,反过来,导致某些细胞分裂素,多聚胺与脱落酸根浓度的变化,从而促进新幼苗生长。这一观点,通过现阶段的试验可以得出。试验结果表明,植物根系所富集的腐植酸能显著增加植物幼苗的生长,这与植物根系H+-ATP酶活性增强有关,这种活性表现在植物幼芽中硝酸盐浓度的增加,根系浓度降低。这些作用与细胞分裂素和多胺物质的浓度在植物幼芽中显著提高是相伴随的,与植物根系浓度降低有关。同样地,多种细胞分裂素在植物幼芽和根系分布的变化与多种矿物营养素在植物幼芽和根系分布的显著变化是协调一致的。试验结果表明,腐植酸对黄瓜幼苗生长的促进作用与硝酸根的浓度直接有关,而硝酸根浓度的变化又影响了细胞分裂素和多胺物质在植物幼苗中的富集。 | Vero nica Mora Eva Bacaicoa Angel-Maria Zamarreo Elena Aguirre Maria Garnica Marta Fuentes Jose-Maria Garc a-Mina 张世万 周霞萍 | 2012 | 腐植酸2012，，2： | 8 |
| 2 | Impaired T-cell differentiation in diabetic foot ulceration显示文摘Foot ulceration is one of the most debilitating complications associated with diabetes,but its cause remains poorly understood.Several studies have been undertaken to understand healing kinetics or find possible therapies to enhance healing.However,few studies have been directed at understanding the immunological alterations that could influence wound healing in diabetes.In this study,we analysed the T-cell receptor(TCR)repertoire diversity in TCR-αβ^(+)T cells.We also analysed the distribution and phenotype of T cells obtained from the peripheral blood of healthy controls and diabetic individuals with or without foot ulcers.Our results showed that diabetic individuals,especially those with foot ulcers,have a significantly lower naive T-cell number and a poorer TCR-Vβrepertoire diversity.We also showed that the reduced TCR-Vβrepertoire diversity in diabetic individuals was mainly owing to the accumulation of effector T cells,the major source of tumour necrosis factor-αproduction,which was even more pronounced in patients with acute foot ulceration.Moreover,the expression of several inflammatory chemokine receptors was significantly reduced in diabetic patients.In conclusion,effector T-cell accumulation and TCR repertoire diversity reduction appear to precede the development of foot ulcers.This finding may open new immunological therapeutic possibilities and provide a new prognostic tool in diabetic wound care. | João Moura João Rodrigues Marta Gonçalves Cláudia Amaral Margarida Lima Eugénia Carvalho | 2017 | Cellular & Molecular Immunology2017，14，9： | 6 |
| 3 | Mercury in sediments and vegetation in a moderately contaminated salt marsh (Tagus Estuary, Portugal)显示文摘Depth variations of total mercury (Hg) and methylmercury (MeHg) concentrations were studied in cores from non-colonized sediments, sediments colonized by Halimione portulacoides, Sarcocornia fruticosa and Spartina maritima and belowground biomass, in a moderately contaminated salt marsh (Tagus Estuary, Portugal). Concentrations in belowground biomass exceeded up to 3 (Hg) and 15 (MeHg) times the levels in sediments, and up to 198 (Hg) and 308 (MeHg) times those found in aboveground parts. Methylmercury in colonized sediments reached 3% of the total Hg, 50 times above the maximum values found in non-colonized sediments. The absence of correlations between total Hg concentrations in sediments and the corresponding MeHg levels suggested that methylation was only dependent on the environmental and microbiological factors. The analysis of belowground biomass at high-depth resolution (2 cm) provided evidence that Hg and MeHg were actively absorbed from sediments, with higher enrichment factors at layers where higher microbial activity was probably occurring. The results obtained in this study indicated that the biotransformation of Hg to the toxic MeHg could increase the toxicity of plant-colonized sediments. | Joao Canário Carlos Vale Laurier Poissant Marta Nogueira Martin Pilote Vasco Branco | 2010 | Journal of Environmental Sciences2010，22，8： | 4 |
| 4 | No evidence of HPV DNA in esophageal squamous cell carcinoma in a population of Southern Brazil显示文摘AIM:To investigate the association between human papillomavirus(HPV)and esophageal squamous cell carcinoma(ESCC)in southern Brazil.METHODS:We studied 189 esophageal samples from125 patients from three different groups:(1)102 biopsies from 51 patients with ESCC,with one sample from the tumor and another from normal esophageal mucosa distant from the tumor;(2)50 esophageal biopsies from 37 patients with a previous diagnosis of head and neck squamous cell carcinoma(HNSCC);and(3)37 biopsies from esophageal mucosa with normal appearance from 37 dyspeptic patients,not exposed to smoking or alcohol consumption.Nested-polymerase chain reaction(PCR)with the MY09/11 and GP5/6 L1primers was used to detect HPV L1 in samples fixed in formalin and stored in paraffin blocks.All PCR reactions were performed with a positive control(cervicovaginal samples),with a negative control(Human Genomic DNA)and with a blank reaction containing all reagents except DNA.We took extreme care to prevent DNA contamination in sample collection,processing,and testing.RESULTS:The histological biopsies confirmed the diagnosis of ESCC in 52 samples(51 from ESCC group and 1 from the HNSCC group)and classified as well differentiated(12/52,23.1%),moderately differentiated(27/52,51.9%)or poorly differentiated(7/52,13.5%).One hundred twenty-eight esophageal biopsies were considered normal(51 from the ESCC group,42 from the HNSCC group and 35 from dyspeptic patients).Nine had esophagitis(7 from the HNSCC and 2 from dyspeptic patients).Of a total of 189 samples,only 6 samples had insufficient material for PCR analysis:1 from mucosa distant from the tumor in a patient with ESCC,3from patients with HNSCC and 2 from patients without cancer.In 183 samples(96.8%)GAPDH,G3PDH and/orβ-globin were amplified,thus indicating the adequacy of the DNA in those samples.HPV DNA was negative in all the 183 samples tested:52 with ESCC,9 with esophagitis and 122 with normal esophageal mucosa.CONCLUSION:There was no evidence of HPV infection in different ESCC from southern Brazil. | Luís Carlos Moreira Antunes Joo Carlos Prolla Antonio de Barros Lopes Marta Pires da Rocha Renato Borges Fagundes | 2013 | World Journal of Gastroenterology2013，19，39： | 4 |
| 5 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 6 | Superplasticity of a friction stir processed overaged WE54 magnesium alloy显示文摘The coarse-grained WE54 magnesium alloy was heat treated in order to have minimum hardness minimizing the effects of precipitates and solid solution. Friction stir processing(FSP) was applied in severe conditions to obtain fine, equiaxed and highly misoriented grains, with grain sizes even less than 1 μm. The high severity of processing demonstrated to have a strong impact in the microstructure. Consequently,the processed materials exhibited excellent superplasticity at the high strain rate 10^(-2)s^(-1), and temperatures between 300 and 400 ℃. The maximum tensile superplastic elongation of 756% was achieved at 400 ℃ thanks to the operation of grain boundary sliding mechanism(GBS). Besides the new data obtained through tensile testing, the paper deals with a transcendental question regarding the large differences in strain rate values at a given stress in the superplastic regime at maximum elongation compared to other magnesium-based alloys. With this is mind, 19 magnesium alloys from 22 different investigations were analyzed to give some light to this behavior that never was treated before. It is proposed that this behavior has to be attributed to the accommodation process, necessary for GBS to occur, which is hindered by reinforcing solutes. | Oscar A.Ruano Marta Alvarez-Leal Alberto Orozco-Caballero Fernando Carreño | 2022 | Journal of Magnesium and Alloys2022，10，11： | 2 |
| 7 | Estrogen receptor-[alpha] signaling in osteoblast progenitors stimulates cortical bone accrual显示文摘 | Almeida Maria Iyer Srividhya Martin-Millan Marta Bartell Shoshana M Han Li Ambrogini Elena Onal Melda Xiong Jinhu Weinstein Robert S Jilka Robert L O’Brien Charles A Manolagas Stavros C | 2013 | Journal of Clinical Investigation2013，，1： | 1 |
| 8 | Growth inhibition by gamma rays affects lipids and fatty acids in garlic sprouts during storage显示文摘 | Mónica B. Pérez Marta I. Avelda?o Clara A. Croci | 2007 | Postharvest Biology and Technology2007，，2： | 1 |
| 9 | Color Doppler imaging of fibroadenomas of the breast with histophathologie correlation显示文摘 | Selwyn S T Orith F R Marta M O | 2004 | J Clin Ultrasound2004，32，2： | 1 |
| 10 | FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex显示文摘 | Marta Muzio Arul M Chinnaiyan Frank C Kischkel Karen O’Rourke Andrej Shevchenko Jian Ni Carsten Scaffidi James D Bretz Mei Zhang Reiner Gentz Matthias Mann Peter H Krammer Marcus E Peter Vishva M Dixit | 1996 | Cell1996，，： | 1 |
| 11 | Mercury and Chlorinated Pesticides on the Highest Level of the Food Web as Exemplified by Herring from the Southern Baltic and African Penguins from the Zoo显示文摘 | Lucyna Falkowska Andrzej R. Reindl Emilia Szumi?o Justyna Kwa?niak Marta Staniszewska Magdalena Be?dowska Anita Lewandowska Izabela Krause | 2013 | Water, Air, & Soil Pollution2013，，5： | 1 |
| 12 | Manufacture of Cheese Made from CO2-Treated Milk显示文摘 | ANTONIA M MARTA C AGUSTIN O | 1995 | J Dairy Sci1995，，： | 1 |
| 13 | A matrix approach coupled with Monte Carlo techniques for solving the net radiative balance of the urban b!ock显示文摘 | MARTA J N O P HEIDER J P G PAUIO M C F | 2007 | Boundary-Layer Meteorology2007，122，1： | 1 |
| 14 | <ce:link locator='fx1'/> 13 C-Mixed Triglyceride Breath Test to Assess Oral Enzyme Substitution Therapy in Patients With Chronic Pancreatitis显示文摘 | J. Enrique Domínguez–Mu?oz Julio Iglesias–García María Vilari?o–Insua Marta Iglesias–Rey | 2007 | Clinical Gastroenterology and Hepatology2007，，4： | 1 |
| 15 | Seasonal and spatial variability of free-living bacterial community eomposition along an estuarine gradient (Ria de Aveiro, Portugal) 显示文摘 | Henriques Isabel S Alves Artur Tac a o Marta | 2006 | Estuarine Coastal and Shelf Science2006，68，12： | 1 |
| 16 | Food preservative based on propolis:Bacteriostatic activity of propolis polyphenols and flavonoids upon Escherichia col显示文摘 | Enzo A T Edmundo R Marta E O | 2007 | Food Chemistry2007，1025，： | 1 |
| 17 | The influence of environmental bacteria in freshwater stingray wound-healing显示文摘 | Marta O D M6rcia R Franzolin Marina Tavares dos Anjos | 2011 | Toxicon2011，58，： | 1 |
| 18 | Glucosamine sulfate use and delay of progression of knee osteoarthritis显示文摘 | Pavelka K Gatterova J Marta O | 2002 | Arch Intern Med2002，162，8： | 1 |
| 19 | Assessment of Trace Aluminium Content in Parenteral Solutions by Combined Cloud Point Preconcentration-flow Injection Inductively Coupled Plasma Optical Emission Spectrometry显示文摘 | Lorena L Sombra Marta O Luconi Liliana P. Fernandez | | 0，，： | 1 |
| 20 | Knowledge spillovers in science and technology parks: How can firms benefit most? 显示文摘 | Isabel D V Marta F O | 2014 | The Journal of Technology Transfer2014，，1： | 1 |
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