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5篇 您的检索式:作者名="Martin Sager"
    题名 作者 年代 出处 被引量
1Vacuum assisted closure in vascular surgery 显示文摘Beno M Martin J Sager P 2011Bratisl Lek Listy2011,112,5:1
2Vacuum assisted closure invascular surgery显示文摘Ben0 M Martin J Sager P 2011Bratisl Lek Listy2011,112,5:1
3Cysteamine effects on growth hormone secretion in the male rat显示文摘Millard W J Sager S M Badger T M and S B Martin 1983Endocrinology1983,112,:1
4Comparison of Effectiveness of Rosuvastatin Versus Atorvastatin on the Achievement of Combined C-Reactive Protein (<2 mg/L) and Low-Density Lipoprotein Cholesterol (<70 mg/dl) Targets in Patients With Type 2 Diabetes Mellitus (from the ANDROMEDA Stu显示文摘D. John Betteridge J. Martin Gibson Philip T. Sager 2007The American Journal of Cardiology2007,,8:1
5Human iPSC-derived iMSCs improve bone regeneration in mini-pigs显示文摘Autologous bone marrow concentrate(BMC)and mesenchymal stem cells(MSCs)have beneficial effects on the healing of bone defects.To address the shortcomings associated with the use of primary MSCs,induced pluripotent stem cell(iPSC)-derived MSCs(iMSCs)have been proposed as an alternative.The aim of this study was to investigate the bone regeneration potential of human iMSCs combined with calcium phosphate granules(CPG)in critical-size defects in the proximal tibias of mini-pigs in the early phase of bone healing compared to that of a previously reported autograft treatment and treatment with a composite made of either a combination of autologous BMC and CPG or CPG alone.iMSCs were derived from iPSCs originating from human fetal foreskin fibroblasts(HFFs).They were able to differentiate into osteoblasts in vitro,express a plethora of bone morphogenic proteins(BMPs)and secrete paracrine signaling-associated cytokines such as PDGF-AA and osteopontin.Radiologically and histomorphometrically,HFF-iMSC+CPG transplantation resulted in significantly better osseous consolidation than the transplantation of CPG alone and produced no significantly different outcomes compared to the transplantation of autologous BMC+CPG after 6 weeks.The results of this translational study imply that iMSCs represent a valuable future treatment option for load-bearing bone defects in humans.Pascal Jungbluth Lucas-Sebastian Spitzhorn Jan Grassmann Stephan Tanner David Latz Md Shaifur Rahman Martina Bohndorf Wasco Wruck Martin Sager Vera Grotheer Patric Kropil Mohssen Hakimi Joachim Windolf Johannes Schneppendahl James Adjaye 2019Bone Research2019,7,4:0
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