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| 1 | Two-week treatment with proton pump inhibitor is sufficient for healing post endoscopic submucosal dissection ulcers显示文摘AIM:To investigate the optimum period of treatment for post endoscopic submucosal dissection(ESD)ulcers.METHODS:Patients who underwent ESD for gastric cancer were randomized to two groups and treated with esomeprazole 20 mg per day for 4 wk(4W group)or 2 wk(2W group).At 4 wk after ESD,we measured the size of the artificial ulcers by endoscopy and determined the ulcer healing rate,compared with the size of the ESD specimens.This randomized controlled trial study was approved by our ethics committee and registered in the UMIN Clinical Trial Registry.RESULTS:A total of 60 consecutive patients were included in the study.All patients received rebamipide 300 mg per day for 4 wk.One patient in 2W group who showed bleeding within two weeks and received endoscopic treatment was excluded from further analysis.The numbers of patients with ulcers in the healing/scar stage in the 2W and 4W groups at 4 wk after ESD were 20/6 and 28/5,respectively,with no significant difference.The ulcer healing rate in the 2W and 4W groups were 96.1%[95%confidence interval(CI):94.6%-97.55]vs 94.8%(95%CI:92.6%-97.1%),respectively,with no statistical difference(UMIN000006951).CONCLUSION:Two-wk treatment with a proton pump inhibitor is as effective as four-week treatment for healing post ESD ulcers. | Makoto Arai Tomoaki Matsumura Kenichiro Okimoto Arata Oyamada Keiko Saito Shoko Minemura Daisuke Maruoka Takeshi Tanaka Tomoo Nakagawa Tatsuro Katsuno Osamu Yokosuka | 2014 | World Journal of Gastroenterology2014，20，43： | 6 |
| 2 | 在有阴暗胃肠的流血的病人的囊内视镜检查法的计算图象修正的功效显示文摘 AIM:To investigate whether flexible spectral color enhancement(FICE) improves diagnostic yields of capsule endoscopy(CE) for obscure gastro-intestinal bleeding(OGIB).METHODS:The study subjects consisted of 81 patients.Using FICE,there were three different sets with different wavelengths.Using randomly selected sets of FICE,images of CE were evaluated again by two individuals who were not shown the conventional CE reports and findings.The difference between FICE and conventional imaging was examined.RESULTS:The overall diagnostic yields in FICE sets 1,2,3 and conventional imaging(48.1%) were 51.9%,40.7%,51.9% and 48.1%,respectively,which showed no statistical difference compared to conventional imaging.The total numbers of detected lesions per examination in FICE imaging and conventional imaging were 2.5 ± 2.1 and 1.8 ± 1.7,respectively,which showed a significant difference(P = 0.01).CONCLUSION:The diagnostic yield for OGIB is not improved by FICE.However,FICE can detect significantly more small bowel lesions compared to conventional imaging. | Tomoaki Matsumura Makoto Arai Toru Sato Tomoo Nakagawa Daisuke Maruoka Masaru Tsuboi Sachio Hata Eiji Arai Tatsuro Katsuno Fumio Imazeki Osamu Yokosuka | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，9： | 4 |
| 3 | Study of Fluid Flow and Mixing Behaviour of a Vacuum Degasser显示文摘 | M. Mondal N. Maruoka S. Kitamura G. Gupta H. Nogami H. Shibata | 2012 | Transactions of the Indian Institute of Metals2012，，3： | 2 |
| 4 | A convergent,homochiral bis(amino alcohol) for obtaining high enantioselectivity in the addition of diethylzinc to aldehydes显示文摘 | Ooi T Saito A Maruoka K | 2001 | Chemistry Letters2001，，11： | 1 |
| 5 | Elevated serum leptin concentrations in women with components of multiple risk factor clustering syndrome显示文摘 | Matsubara M Chiba H Maruoka S | 2000 | J Atheroscler Thromb2000，7，4： | 1 |
| 6 | Decreased plasma adiponectin concentrations in women with dyslipidemia显示文摘 | Matsubara M Maruoka S Katayose S | 2002 | J Clin Endocrinol Metab2002，87，6： | 1 |
| 7 | Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women 显示文摘 | Matsttbara M Maruoka S Katayose S | 2003 | Eur J Endocrinol2003，147，： | 1 |
| 8 | Decreased plasma adiponectin concentrations in women with dyslipidemia显示文摘 | Matsubara M Maruoka S Katayose S | 2002 | J Clin Endocrinol Metab2002，87，6： | 1 |
| 9 | A WD-domain protein that is associated with and phosphorylated by the type 显示文摘 | Chen RH Miettinen P J Maruoka EM | 1995 | Nature1995，377，6549： | 1 |
| 10 | In-creased intensities of fas expression on peripheral T - cell subsetsin severe autoimmune thyroid disease 显示文摘 | MARUOKA H WATANABA M MATSUZUKA F | 2004 | Thyroid2004，14，6： | 1 |
| 11 | Decreased plasma adiponec2tin concentrations in women with dyslipidemia显示文摘 | MatsubaraM Maruoka S Katayose S | 2002 | J Clin Endoerinol Metab2002，87，6： | 1 |
| 12 | Increased intensities of fas expression on peripheral T-cell subsets in severe autoimmune thyroid disease显示文摘 | Maruoka H Watanaba M Matsuzuka F | 2004 | Thyroid2004，14，6： | 1 |
| 13 | Heat Recovery of LDG by Utili-zing Latent Heat and Reaction Heat for Producing Meth-anol 显示文摘 | Nobuhiro MARUOKA | 2002 | ISU International2002，42，11： | 1 |
| 14 | Thermal stress analysis of PCM encapsulation for heat recovery of high temperature waste heat 显示文摘 | Maruoka N Akiyama T | 2003 | Journal of chemical engineering of Japan2003，36，7： | 1 |
| 15 | Recent advances in asymmetricphase-transfer catalysis 显示文摘 | Ooi T Maruoka K | 2007 | Angew Chem Int Ed2007，46，： | 1 |
| 16 | Enantioselective amino acidsynthesis by chiral phase-transfer catalysis 显示文摘 | Maruoka K Ooi T | 2003 | Chem Rev2003，103，： | 1 |
| 17 | Development of coronary collateral circulation in left circumflex Ameroid-occluded swine myocardium显示文摘 | Roth DM Maruoka Y Rogers J | 1987 | Am J Physiol1987，253，52： | 1 |
| 18 | Inverse relationship between plasma adiponectin and leptin concentrations in normalweight and obese women 显示文摘 | Matsubara M Maruoka S Katayose S | 2002 | Eur J Endocrinol2002，147，2： | 1 |
| 19 | Incremental diagnostic value of SPECT/CT with3q scintigraphy after radioiodine therapy in patients with well-differentiated thyroid carci- noma 显示文摘 | Maruoka Y Abe K Baba S | 2012 | Radiology2012，265，3： | 1 |
| 20 | Biocompatibility of polyvinylalcohol gel as a vitreous substitute 显示文摘 | Maruoka S Matsuura T Kawasaki K | 2006 | Curr Eye Res2006，31，78： | 1 |
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