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| 1 | Saccharomyces boulardii Does Not Prevent Relapse of Crohn’s Disease显示文摘 | Arnaud Bourreille Guillaume Cadiot Gérard Le Dreau David Laharie Laurent Beaugerie Jean–Louis Dupas Philippe Marteau Patrick Rampal Dominique Moyse Ashraf Saleh Marie–Emmanuelle Le Guern Jean–Paul Galmiche | 2013 | Clinical Gastroenterology and Hepatology2013，，8： | 3 |
| 2 | 9种商业消毒剂对猪2型圆环病毒的杀灭效能测试显示文摘养猪业中常用的许多商业消毒剂,都获得了法国农业部批准。然而对其杀灭增殖初期猪2型圆环病毒(PCV2)的效能却不甚了解。用在法国分离到的PCV2悬液来测试9种商业消毒剂的效能,在20℃下病毒悬液与消毒剂作用30 min后,将该混合液过滤和稀释进行脱毒处理以去除对圆环病毒和猪肾细胞系有害的物质,再经一系列稀释后接种于人工培养的猪肾细胞进行免疫过氧化物酶单层细胞试验(IPMA)测定PCV2的感染性。结果表明,用碘类和苯酚类消毒剂并不能减少病毒滴度。在此着重介绍其他消毒剂效能(病毒滴度减少量≥1.61 log_(10)),其中5种消毒剂:一种含过一硫酸氢钾,另两种含一种季铵盐、一到三种醛、次氯酸钠和氢氧化钠,在标准浓度下或1.5~4倍低于标准浓度时可显著杀灭PCV2;其余两种,其中一种含过一硫酸氢钾,另一种含过氧乙酸和过氧化氢,在标准浓度下或2倍高于标准浓度时也可杀灭PCV2。 | Hélène Martin Marie-Frédérique Le Potier Pierre Maris 杨满军 | 2009 | 今日养猪业2009，，3： | 2 |
| 3 | Cell:癌基因“遗传平衡”或会影响患者对癌症疗法的反应显示文摘进行癌症疗法的选择越来越需要确定肿瘤细胞中是否含有一些特殊突变的癌基因会驱动癌细胞异常生长。并且确定是否癌细胞会对特殊药物耐受或敏感.近日来自加州大学旧金山分校的研究人员就通过研究发现。以常见的癌基因KRAs突变为例。患者对疗法的反应往往会随着肿瘤的不断进化而发生改变。相关研究刊登于国际杂志Cell上。 | Michael R. Burgess Eugene Hwang Rana Mroue Craig M. Bielski Anica M. Wandler Benjamin J. Huang Ari J. Firestone Amy Young Jennifer A. Lacap Lisa Crocker Saurabh Asthana Elizabeth M. Davis Jin Xu Keiko Akagi Michelle M. Le Beau Qing Li Benjamin Haley David Stokoe Deepak Sampath Barry S. Taylor Marie Evangelista Kevin Shannon | 2017 | 现代生物医学进展2017，17，18： | 2 |
| 4 | <ce:link locator='fx1'/> <ce:link locator='fx2'/> Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis显示文摘 | Rami Moucari Tarik Asselah Dominique Cazals–Hatem Hélène Voitot Nathalie Boyer Marie–Pierre Ripault Rodolphe Sobesky Michèle Martinot–Peignoux Sarah Maylin Marie–Hélène Nicolas–Chanoine Valérie Paradis Michel Vidaud Dominique Valla Pierre Bedossa Patrick | 2008 | Gastroenterology2008，，2： | 2 |
| 5 | Direct growth of ZnO nanowires on civil engineering materials:smart materials for supported photodegradation显示文摘Photocatalysis is one of the most promising processes for treating air and water pollution.Innovative civil engineering materials for environmental depollution by photocatalysis have already been synthesized by incorporating TiO_(2) or ZnO nanoparticles in cement.This method suffers from two flaws:first,most of the NPs are incorporated into the cement and useless for photocatalysis;second,rain and wind could spread the potentially carcinogenic nanoparticles from the cement surface into nature.Thus,we propose the efficient synthesis of nontoxic and biocompatible ZnO nanostructures solely onto the surface of commercially available concrete and tiling pavements by a low-cost and lowtemperature hydrothermal method.Our samples exhibited enhanced photocatalytic activity for degrading organic dyes in aqueous media,and dye molecules are commonly used in the pharmaceutical,food,and textile industries.Durability studies showed no loss of efficiency after four photocatalysis experiments.Such supported structures,which are easy to implement onto the varying surfaces of commercially available materials,are promising for integration into civil engineering surfaces for environmental depollution in our daily life. | Marie Le Pivert Romain Poupart Martine Capochichi-Gnambodoe Nathan Martin Yamin Leprince-Wang | 2019 | Microsystems & Nanoengineering2019，5，1： | 2 |
| 6 | Disturbance and landscape dynamics in the Chequamegon National Forest Wisconsin, USA, from 1972 to 2001显示文摘 | Mary K. Bresee Jim Le Moine Stephen Mather Kimberley D. Brosofske Jiquan Chen Thomas R. Crow John Rademacher | 2004 | Landscape Ecology2004，，3： | 1 |
| 7 | Estimating aboveground biomass using Landsat 7 ETM+ data across a managed landscape in northern Wisconsin, USA显示文摘 | Daolan Zheng John Rademacher Jiquan Chen Thomas Crow Mary Bresee James Le Moine Soung-Ryoul Ryu | 2004 | Remote Sensing of Environment2004，，3： | 1 |
| 8 | Antioxidant and antitumoural activities of some Phaeophyta from Brittany coasts显示文摘 | Mayalen Zubia Marie Sophie Fabre Véronique Kerjean Klervi Le Lann Valérie Stiger-Pouvreau Marilyne Fauchon Eric Deslandes | 2009 | Food Chemistry2009，，3： | 1 |
| 9 | Differential Expression of the Rat γ-Glutamyl Transpeptidase Gene Promoters along with Differentiation of Hepatoblasts into Biliary or Hepatocytic Lineage显示文摘 | Nathalie Holic Takanobu Suzuki Anne Corlu Dominique Couchie Marie No?le Chobert Christiane Guguen-Guillouzo Yannick Laperche | 2000 | The American Journal of Pathology2000，，2： | 1 |
| 10 | High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA显示文摘Normal high-density lipoprotein(nHDL)can induce angiogenesis in healthy individuals.However,HDL from patients with coronary artery disease undergoes various modifications,becomes dysfunctional(dHDL),and loses its ability to promote angiogenesis.Here,we identified a long non-coding RNA,HDRACA,that is involved in the regulation of angiogenesis by HDL.In this study,we showed that nHDL downregulates the expression of HDRACA in endothelial cells by activating WW domain-containing E3 ubiquitin protein ligase 2,which catalyzes the ubiquitination and subsequent degradation of its transcription factor,Kruppel-like factor 5,via sphingosine 1-phosphate(S1P)receptor 1.In contrast,dHDL with lower levels of S1P than nHDL were much less effective in decreasing the expression of HDRACA.HDRACA was able to bind to Ras-interacting protein 1(RAIN)to hinder the interaction between RAIN and vigilin,which led to an increase in the binding between the vigilin protein and proliferating cell nuclear antigen(PCNA)mRNA,resulting in a decrease in the expression of PCNA and inhibition of angiogenesis.The expression of human HDRACA in a hindlimb ischemia mouse model inhibited the recovery of angiogenesis.Taken together,these findings suggest that HDRACA is involved in the HDL regulation of angiogenesis,which nHDL inhibits the expression of HDRACA to induce angiogenesis,and that dHDL is much less effective in inhibiting HDRACA expression,which provides an explanation for the decreased ability of dHDL to stimulate angiogenesis. | Zhi-Wei Mo Yue-Ming Peng Yi-Xin Zhang Yan Li Bi-Ang Kang Ya-Ting Chen Le Li Mary GSorci-Thomas Yi-Jun Lin Yang Cao Si Chen Ze-Long Liu Jian-Jun Gao Zhan-Peng Huang Jia-Guo Zhou Mian Wang Guang-Qi Chang Meng-Jie Deng Yu-Jia Liu Zhen-Sheng Ma Zuo-Jun Hu Yu-Gang Dong Zhi-Jun Ou Jing-Song Ou | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 1 |
| 11 | Study of wheat gluten plasticization with fatty acids 显示文摘 | Marion P Andre'as Redl Marie - He'le'ne M | 2003 | Polymer2003，，44： | 1 |
| 12 | Numerical solution of semilinear integro-differential equations of parabolic type with nonsmooth data显示文摘 | Marie Noelle Le Roux Thomee V | 1989 | SIAM Journal of Numerical Analysis1989，26，： | 1 |
| 13 | Simultaneous determination of optical and chemical purities of a drug with two chiral centers by liquid chromatography-circular dichroism detection on a non-chiral stationary phase显示文摘 | Marie Lecoeur-Lorin Raphael Del6p~e Mich~le Adamczyk etal | 2008 | Journal of Chromatography A2008，1206，： | 1 |
| 14 | Deciphering the evolution of herbicide resistance in weeds显示文摘 | Christophe Délye Marie Jasieniuk Valérie Le Corre | 2013 | Trends in Genetics2013，，： | 1 |
| 15 | Surgical advances in the treatment of neuromuscular scoliosis显示文摘Neuromuscular disorders are a group of diseases affecting the neuro-musculo-skeletal system. Children with neuromuscular disorders frequently develop progressive spinal deformities with cardio-respiratory compromise in the most severe cases. The incidence of neuromuscular scoliosis is variable, inversely correlated with ambulatory abilities and with a reported risk ranging from 80% to 100% in non-ambulatory patients. As surgical and peri-operative techniques have improved, more severely affected children with complex neuromuscular deformities and considerable co-morbidities are now believed to be candidates for extensive surgery for spinal deformity. This article aimed to provide a comprehensive review of how neuromuscular spinal deformities can affect normal spine balance and how these deformities can be treated with segmental instrumentation and sub-laminar devices. Older concepts have been integrated with newer scientific data to provide the reader with a basis for better understanding of how treatment of neuromuscular scoliosis has evolvedover the past few decades. Recent advances, as well as challenges that remain to be overcome, in the surgical treatment of neuromuscular curves with sub-laminar devices and in the management of post-operative infections are outlined. | Federico Canavese Marie Rousset Benoit Le Gledic Antoine Samba Alain Dimeglio | 2014 | World Journal of Orthopedics2014，5，2： | 1 |
| 16 | Delayed freezing on water repellent material 显示文摘 | Tourkine Piotr Merrer Marie Le Quere David | 2009 | Langmuir2009，25，13： | 1 |
| 17 | 5-HT3 receptor antagonist:Are they all same? 显示文摘 | Kim de B Lianne C Marie Le F | 2002 | Cancer Today2002，，： | 1 |
| 18 | <ce:link locator='fx1'/> <ce:link locator='fx2'/> Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis显示文摘 | Rami Moucari Tarik Asselah Dominique Cazals–Hatem Hélène Voitot Nathalie Boyer Marie–Pierre Ripault Rodolphe Sobesky Michèle Martinot–Peignoux Sarah Maylin Marie–Hélène Nicolas–Chanoine Valérie Paradis Michel Vidaud Dominique Valla Pierre Bedossa Patrick | 2008 | Gastroenterology2008，，2： | 1 |
| 19 | Tolerance of liver biopsy in a tertiary care center: comparison of the percutaneous and the transvenous route in 143 prospectively followed patients显示文摘 | Bogdan Procopet Christophe Bureau Sophie Métivier Janick Selves Marie Angèle Robic Camille Christol Mircea Grigorescu Jean-Pierre Vinel Jean-Marie Péron | 2012 | European Journal of Gastroenterology & Hepatology2012，，10： | 1 |
| 20 | Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk显示文摘 | Boulet Marie Miche?le Chevrier Genevie?e?ve Grenier-Larouche Thomas Pelletier Me?e?e?lissa Nadeau Me?e?e?e?lanie Scarpa Julia Prehn Cornelia Marette Andre?e?e?e?e? Adamski Jerzy Tchernof Andre?e?e?e?e?e? | 2015 | AJP: Endocrinology and Metabolism2015，，： | 1 |
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