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| 1 | Clinical and immunologic effects of faecal microbiota transplantation in a patient with collagenous colitis显示文摘One to six percent of patients with microscopic colitis are refractory to medical treatment. The effect of faecal microbiota transplantation(FMT) in active collagenous colitis(CC) has, to the best of our knowledge, never been reported before. Here, we report the effect of repeated FMT in a patient with CC. The patient presented with severe symptoms including profuse diarrhea and profound weight loss. Although she responded to budesonide in the beginning, she became gradually refractory to medical treatment, and was therefore treated with FMT. The patient remained in remission for 11 mo after the third faecal transplantation. The immunomodulatory effect of the therapy was evaluated using flow cytometry, which showed alterations in the profile of intraepithelial and lamina propria lymphocyte subsets after the second transplantation. Our observations indicate that FMT can have an effect in CC, which support the hypothesis that luminal factors, influencing the intestinal microbiota, are involved in the pathogenesis of CC. | Sezin Günaltay Lech Rademacher Elisabeth Hultgren Hornquist Johan Bohr | 2017 | World Journal of Gastroenterology2017，23，7： | 4 |
| 2 | 采用净能方法配制猪日粮显示文摘二十世纪初在美国出现了以净能(NE)确定动物日粮中能量的方法,起初该方法仅被应用于牛.然而,实践证明它对于大部分商业日粮配方特别是单胃动物(尤其是猪)的配方并不实用.对于猪的日粮,普遍使用消化能(DE)的方法.但是,如今合成氨基酸很容易可得到以及人们追求低日粮粗蛋白,导致消化能方法逐渐被废弃.同欧洲和其它地区一样,北美洲在配制猪日粮时也开始以净能方法取代消化能方法. | Jonathan Goodson Meike Rademacher 林月霞 | 2005 | 国外畜牧学(猪与禽)2005，，6： | 2 |
| 3 | 蛋氨酸和蛋氨酸羟基类似物对猪的生物学效价显示文摘蛋氨酸缺乏日粮中添加DL-蛋氨酸和液体蛋氨酸羟基类似物增加了仔猪和生长猪的氮沉积,明显改善了仔猪的生产性能,这表明试验结果是在蛋氨酸敏感区域内测得。液体蛋氨酸羟基类似物对猪的相对生物学效价只有DL-蛋氨酸的65%,远低于液体蛋氨酸羟基类似物88%的商业含量。这些结果再次验证在家禽的研究结果,即液体蛋氨酸羟基类似物相对DL-蛋氨酸的效价只有65%。因此,液体蛋氨酸羟基类似物对猪的生物学效价只有65%。 | Meike Rademacher 张维军 黄军儿 | 2001 | 四川畜牧兽医2001，28，3： | 2 |
| 4 | Self-expanding metal stents for the palliation of malignant gastric outlet obstruction in patients with peritoneal carcinomatosis显示文摘AIM To evaluate the efficacy of self-expanding metal stents(SEMS) for the palliation of malignant gastric outlet obstruction in patients with and without peritoneal carcinomatosis(PC).METHODS We performed a retrospective analysis of 62 patients who underwent SEMS placement for treatment of malignant gastroduodenal obstruction at our hospital over a six-year period. Stents were deployed through the scope under combined fluoroscopic and endoscopic guidance. Technical success was defined as successful stent placement and expansion. Clinical success was defined as an improvement in the obstructive symptoms and discharge from hospital without additional parenteral nutrition. According to carcinomatosis status, patients were assigned into groups with or without evidence of peritoneal disease.RESULTS In most cases, obstruction was caused by pancreatic(47%) or gastric cancer(23%). Technical success was achieved in 96.8%(60/62), clinical success in 79%(49/62) of all patients. Signs of carcinomatosis were identified in 27 patients(43.5%). The diagnosis was confirmed by pathology or previous operation in 7 patients(11.2%) and suspected by CT, MRI or ultrasound in 20 patients(32.2%). Presence of carcinomatosis was associated with a significantly lower clinical success rate compared to patients with no evidence of peritoneal disease(66.7% vs 88.6%, P = 0.036). There was no significant difference in overall survival between patients with or without PC(median 48 d vs 70 d, P = 0.21), but patients showed significantly longer survival after clinical success of SEMS placement compared to those experiencing clinical failure(median 14.5 d vs 75 d, P = 0.0003).CONCLUSION Given the limited therapeutic options and a clinical success rate of at least 66.7%, we believe that SEMS are a reasonable treatment option in patients with malignant gastric outlet obstruction with peritoneal carcinomatosis. | Christoph Rademacher Matthias Bechtler Steffen Schneider Bettina Hartmann Johannes Striegel Ralf Jakobs | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 5 | Extracorporeal liver support therapy with Prometheus in patients with liver failure in the intensive care unit 显示文摘 | Oppert M Rademacher S Petrasch K | 2009 | Ther Apber Dial2009，13，： | 1 |
| 6 | Recombinant antibody 2G12 produced in maize endosperm efficiently neutralizes HIV-1 and contains predominantly single-GIcNAc N-glycans显示文摘 | Rademacher T Sack M Arcalis E | 2008 | Plant J2008，6，2： | 1 |
| 7 | Artificial extraeorporeal liver support therapy in pa- tients with severe liver failure 显示文摘 | Rademacher S | 2011 | Expert Rev Gastroenterol Hepa- tol2011，5，5： | 1 |
| 8 | Efficient use of prohexadi- one-Ca in pome fruits显示文摘 | Rademacher W R Kober | 2003 | Europ J Hort Sci2003，68，： | 1 |
| 9 | A dynamic model of patterns of deforestation and their effect on the ability of the Brazilian Amazonia to provide ecosystem services显示文摘 | PORTELA R RADEMACHER I | 2001 | Ecological Modelling2001，143，： | 1 |
| 10 | Endothelialization of PTFE vascular grafts under flow induces significant cellchanges显示文摘 | Rademacher A Paulitschke M Meyer R | 2001 | lnt J Artif Organs2001，24，4： | 1 |
| 11 | Disturbance and landscape dynamics in the Chequamegon National Forest Wisconsin, USA, from 1972 to 2001显示文摘 | Mary K. Bresee Jim Le Moine Stephen Mather Kimberley D. Brosofske Jiquan Chen Thomas R. Crow John Rademacher | 2004 | Landscape Ecology2004，，3： | 1 |
| 12 | Impact of Prohexadione Ca on the vegetative and re- productive performance Of apple and pear trees显示文摘 | Rademacher W Saarloos K Garuz-Porte J A | 2004 | Eur J Hortic Sci2004，69，： | 1 |
| 13 | Relation of blood pressure and body mass index during childhood to cardiovascular risk factor levels in young adults显示文摘 | Rademacher ER Jacobs DR Moran A | 2009 | Hypertension2009，27，9： | 1 |
| 14 | Estimating aboveground biomass using Landsat 7 ETM+ data across a managed landscape in northern Wisconsin, USA显示文摘 | Daolan Zheng John Rademacher Jiquan Chen Thomas Crow Mary Bresee James Le Moine Soung-Ryoul Ryu | 2004 | Remote Sensing of Environment2004，，3： | 1 |
| 15 | Comparative NMR-Based metabonomic investigation of the metabolic phenotype associated with tienilic acid and tienilic acid isomer显示文摘 | COEN M RADEMACHER P M ZOU W | | 0，，： | 1 |
| 16 | Parameters af- fecting primary stability of orthodontic mini-implants显示文摘 | Wilmes B Rademacher C Olthoff G | 2006 | J Orofac Orthop2006，67，： | 1 |
| 17 | Evaluation through literature data of the amount and amino acid composition of basal endogenous crude protein at the terminal ileum of pigs显示文摘 | A.J.M Jansman W Smink P van Leeuwen M Rademacher | 2002 | Animal Feed Science and Technology2002，，1： | 1 |
| 18 | Artificial extractor-poreal liver support therapy in patients with severe liver failure显示文摘 | Rademacher S Oppert M Jorres A | 2011 | Ex- pert Rev Gastroenterol Hepatol2011，5，5： | 1 |
| 19 | Parameters affecting primary stability of orthodontic mini-implants 显示文摘 | Wilmes B Rademacher C Ohhoff G | 2006 | J Orofac Orthop2006，67，3： | 1 |
| 20 | On the Transformation of logn(τ)显示文摘 | Rademacher H | 1955 | Indian Math Soc1955，19，： | 1 |
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