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| 1 | Excessive portal flow causes graft failure in extremely small-for-size liver transplantation in pigs显示文摘AIM: To evaluate the effects of a portocaval shunt on the decrease of excessive portal flow for the prevention of sinusoidal microcirculatory injury in extremely smallfor-size liver transplantation in pigs.METHODS: The right lateral lobe of pigs, i.e. the 25%of the liver, was transplanted orthotopically. The pigs were divided into two groups: graft without portocaval shunt (n = 11) and graft with portocaval shunt (n=11).Survival rate, portal flow, hepatic arterial flow, and histological findings were investigated.RESULTS: In the group without portocaval shunt, all pigs except one died of liver dysfunction within 24 h after transplantation. In the group with portocaval shunt,eight pigs survived for more than 4 d. The portal flow volumes before and after transplantation in the group without portocaval shunt were 118.2±26.9 mL/min/100 g liver tissue and 270.5±72.9 mL/min/100 g liver tissue,respectively. On the other hand, in the group with portocaval shunt, those volumes were 124.2±27.8 mL/min/100 g liver tissue and 42.7±32.3 mL/min/100 g liver tissue, respectively (P<0.01). As for histological findings in the group without portocaval shunt, destruction of the sinusoidal lining and bleeding in the peri-portal areas were observed after reperfusion, but these findings were not recognized in the group with portocaval shunt.CONCLUSION: These results suggest that excessive portal flow is attributed to post transplant liver dysfunction after extreme small-for-size liver transplantation caused by sinusoidal microcirculatory injury. | Hong-Sheng Wang Nobuhiro Ohkohchi Yoshitaka Enomoto Masahiro Usuda Shigehito Miyagi Takeshi Asakura Hiroo Masuoka Takashi Aiso Keisuke Fukushima Tomohiro Narita Hideyuki Yamaya Atsushi Nakamura Satoshi Sekiguchi Naoki Kawagishi Akira Sato Susumu Satomi | 2005 | World Journal of Gastroenterology2005，11，44： | 8 |
| 2 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 2 |
| 3 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 4 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 5 | Portal vein pressure is the key for successful liver transplantation of an extremely small graft in the pig model显示文摘 | Takeshi Asakura Nobuhiro Ohkohchi Takashi Orii Nozomi Koyamada Shigeki Tsukamoto Masahide Sato Yoshitaka Enomoto Masahiro Usuda Susumu Satomi | 2003 | Transplant International2003，，6： | 1 |
| 6 | Proxy Signatures: Delegation of the Power to Sign Messages显示文摘 | Mambo Masahiro Usuda Keisuke Okamoto Eiji | 1996 | IEICE Transactions on Fundamentals of Electronics Communications and Computer Sciences1996，79，9： | 1 |
| 7 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 8 | Portal vein pressure is the key for successful liver transplantation of an extremely small graft in the pig model显示文摘 | Takeshi Asakura Nobuhiro Ohkohchi Takashi Orii Nozomi Koyamada Shigeki Tsukamoto Masahide Sato Yoshitaka Enomoto Masahiro Usuda Susumu Satomi | 2003 | Transplant International2003，，6： | 1 |
| 9 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang MD PhD Nobuhiro Ohkohchi MD PhD Yoshitaka Enomoto MD Masahiro Usuda MD Shigehito Miyagi MD Hiroo Masuoka MD Satoshi Sekiguchi MD Naoki Kawagishi MD Keisei Fujimori MD Akira Sato MD Susumu Satomi MD PhD | 2006 | World Journal of Surgery2006，，11： | 1 |
| 10 | Portal vein pressure is the key for successful liver transplantation of an extremely small graft in the pig model显示文摘 | Takeshi Asakura Nobuhiro Ohkohchi Takashi Orii Nozomi Koyamada Shigeki Tsukamoto Masahide Sato Yoshitaka Enomoto Masahiro Usuda Susumu Satomi | 2003 | Transplant International2003，，6： | 1 |
| 11 | Effect of Portocaval Shunt on Residual Extreme Small Liver after Extended Hepatectomy in Porcine显示文摘 | HongSheng Wang Nobuhiro Ohkohchi Yoshitaka Enomoto Masahiro Usuda Shigehito Miyagi Hiroo Masuoka Satoshi Sekiguchi Naoki Kawagishi Keisei Fujimori Akira Sato Susumu Satomi | 2006 | World Journal of Surgery2006，，11： | 1 |
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