|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Coadministration of indomethacin and minocycline attenuates established paclitaxel-induced neuropathic thermal hyperalgesia:Involvement of cannabinoid CB1 receptors显示文摘 | Parvathy SS Masocha W | 2015 | Sci Rep2015，18，10： | 1 |
| 2 | Treatment of African trypanosomiasis with cordycepin and adenosine deaminase inhibitors in a mouse model显示文摘 | Rottenberg M Es Masocha W Ferella Mv | 2005 | J Infect Dis2005，192，9： | 1 |
| 3 | Treatmentof African trypanosomiasis with cordycepin and adenosinedeaminase inhibitiors in a mouse model 显示文摘 | Rottenberg M E Masocha W Ferella M | 2005 | J Infect Dis2005，192，9： | 1 |
| 4 | Systemic lipopolysaccharide (lps) - in- duced microglial activation results in different temporal reduction of cd200 and ed200 receptor gene expression in the brain 显示文摘 | Masocha W | 2009 | J Neuroimmunol2009，214，： | 1 |
| 5 | Role of Na ( + ), K ( + ) - ATPase in morphine - induced antinocieeption 显示文摘 | Masocha W Horvath G Agil A | 2003 | J Pharmacol Exp Ther2003，306，： | 1 |
| 6 | Treatment of African trypanosomiasis with cordycepin and adenosine deaminase inhibitiors in a mouse model 显示文摘 | Rottenberg ME Masocha W Ferella M | 2005 | J Infect Dis2005，192，9： | 1 |
| 7 | EBanking Adoption by Customers in the Rural Milieus of South Africa: A Case of Alice, Eastern Cape, South Africa显示文摘 | MASOCHA R CHILIYA N ZINDIYE S | 2011 | Journal of Business Management2011，5，5： | 1 |
| 8 | Role of Na( + ), K ( + )-ATPase in morphine-induced antinociception 显示文摘 | Masocha W Horvath G Agil A | 2003 | J Pharmacol Exp Ther2003，306，3： | 1 |
| 9 | Systemic lipopolysaccharide(LPS)-induced microglial activatoion results in different temporal reduction of CD200 and CD200 receptor gene expression in the brain 显示文摘 | Masocha W | 2009 | J Neuroimmuno12009，214，12： | 1 |
| 10 | E Banking adoption by customers in the rural milieus of South Africa: A Case of Alice, Eastern Cape, South Africa显示文摘 | Masocha R Chiliya N Zindiye S | 2011 | African Journal of Business Management2011，5，5： | 1 |
| 11 | Role of Na(+),K(+)-ATPase in morphine-induced antinociception显示文摘 | Masocha W Horvath G Agil A | | 0，，03： | 1 |
| 12 | Treatment of African trypanosomiasis with cordycepin and adenosine deaminase inhibitiors in a mouse model显示文摘 | Rottenberg M E Masocha W Ferella M | 2005 | J Infect Dis2005，192，9： | 1 |
| 13 | Treatment of African trypanosomiasis with cordycepin and adenosine deaminase inhibitors in a mouse model显示文摘 | Rottenberg M E Masocha W Ferella M | 2005 | The Journal of Infectious Diseases2005，192，： | 1 |
| 14 | Role of chemokines and cytokines in the neuropathogenesis of African trypanosomiasis显示文摘Trypanosoma brucei spp. cause human African trypanosomiasis(HAT) or sleeping sickness in humans and nagana in animals. The early stages of the disease have no specific symptoms; however, the late stage of the disease involves neurological signs of the disease, including disturbance of sleep patterns from which the disease derives the name sleeping sickness. During the late stage of African trypanosomiasis parasites, increased numbers of white blood cells and levels of cytokines and/or chemokines are found in the brain parenchyma and/or cerebrospinal fluid of animal models and HAT patients. In this mini review, contemporary findings on how chemokines and cytokines are thought to play an important role in the central nervous system invasion by the parasites, inflammation and the neuropathology of the disease are discussed. The levels of various cytokines and chemokines, such as interferongamma(IFN-γ), interleukin-1 beta(IL-1β), IL-6, IL-10, tumor necrosis factor-alpha(TNF-α), C-C motif chemokine 2(CCL2), CCL3, C-X-C motif chemokine 8(CXCL8, IL-8) and CXCL10, in the cerebrospinal fluid(CSF) of HAT patients correlate with the severity or stage of the disease. Thus, these molecules are possible candidates for differentiating between early and late stage HAT. The role of cytokines and chemokines in parasite invasion of the central nervous system is also being eluci-dated. IFN-γ, TNF-α and CXCL-10 are some of the cytokines and chemokines now known to facilitate parasite penetration of the brain parenchyma. Interestingly, they also constitute some of the candidate molecules with potential to differentiate between stage 1 and 2 of HAT. The increased levels of cytokines, such as IL-1β, IL-6, IFN-γ and TNF-α, as well as prostaglandins, during African trypanosomiasis might contribute to the neurological dysfunctions that occur during HAT. | Willias Masocha | 2013 | World Journal of Clinical Infectious Diseases2013，3，4： | 0 |
| 15 | Challenges Facing Zimbabwean Cross Border Traders Trading in South Africa: A Review of Literature显示文摘 | Norman Chiliya Reginald Masocha Stanislous Zindiye | 2012 | Chinese Business Review2012，11，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员