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| 1 | 一种房颤风险评分系统的建立(Framingham心脏研究):基于社区的队列研究显示文摘背景房颤导致了发病率和病死率的显著上升。本研究旨在建立一种预测个体罹患房颤绝对风险的风险评分系统,并提供研究人员评价新危险因素的流程。方法作者评估了Framingham心脏研究中于1968年6月至1987年9月间进行了8044次检测的4764例参与者(55%为女性,年龄45~95岁)。此后,参与者被随访至房颤首发,随访期最长达10年。多变量Coxi回归确认出1(1年内罹患房颤的临床危险因素。次级分析纳入了常规超声心动图检测指标(5152例4参与者,7156次检测)对房颤风险进行再分层评估,并评价超声检测指标能否提高风险预测能力。结果4764例参与者中的457例4(10%)罹患房颤。年龄、性别、体重指数、收缩压、降压治疗、PR间期、有临床意义的心脏杂音及心力衰竭与房颤相关,并被纳入了风险评分模型(除体重指数P=0.08外,其余均为P〈0.05),模型的C统计量为0.78(95%CI0.76~0.80)。10年房颤风险随年龄变化:年龄〈65岁的人群中53例(1%)风险高于15%,而〉65岁的人群中为783例(27%)。为提高预测能力而纳入超声检测指标仅使模型C统计量略微增高,由0.78(95%C10.75~0.80)增至0.79(95%CI0.77~0.82:P=0.005)。超声心动图检测指标并不能改善风险再分层评估(P=0.18)。结论基于社区医疗中易得的临床因素建立的风险评分系统,有助于确认社区个体罹患房颤的风险,评估技术或标志物能否改善风险预测,以及针对高危个体采取预防措施。 | Renate B Schnabel Lisa M Sullivan Daniel Levy Michael J Pencina Joseph M Massaro Ralph B D'Agostino Sr Christopher Newton-Cheh Jennifer F Yamamoto Jared W Magnani Thomas M Tadros William B Kannel Thomas J Wang Patrick T Ellinor Philip A Wolf Ramachanclran S Vasan Emelia J Benjamin 黄刚(译) | 2009 | 世界临床医学2009，，9： | 2 |
| 2 | Biological therapies in rheumatic diseases显示文摘 | Conti F Ceccarelli F Massaro L | 2013 | Clin Ter2013，164，： | 1 |
| 3 | Cerumen of Australian stingless bees (Tetragonula carbonaria): Gas chromatography--mass spectrometry fingerprints and potential anti--inflammatory properties 显示文摘 | Massaro F C Brooks P R Wallace H M | 2011 | Naturwissen-- schaften2011，98，4： | 1 |
| 4 | Association between single-slice measurements of visceral and abdominal subcutaneous adipose tissue with voluf-netric measurements: the Framingham Heart Study显示文摘 | Irlbeck T Massaro J M Bamberg F | 2010 | Int J Obes (Lond)2010，34，4： | 1 |
| 5 | Effects of residential exercise training on heart rate recovery in coronary artery patients显示文摘 | Legramante JM Iellamo F Massaro M | 2007 | Am J Physiol Heart Circ Physiol2007，292，1： | 1 |
| 6 | Stroke as the first manifestation of calcific aortic stenosis显示文摘 | Oliveira-filho J Massaro AR Yamamoto F | 2000 | Cerebrovasc Dis2000，10，： | 1 |
| 7 | Surface and biological evaluation of hydroxyapatite-based coatings on titanium deposited by different techniques显示文摘 | Massaro C Baker M A Cosentino F | 2001 | J Biomed Mater Res(Appl Biomater)2001，58，： | 1 |
| 8 | Anatomical and visual outcomes in high my- opic macular hole (HM-MH) without retinal detachment: a re- view显示文摘 | Alkabes M Pichi F Nucci P Massaro D Durra Medeiros M Cor- costegui B | 2014 | Graefes Arch Clin Exp Ophthalmol2014，252，2： | 1 |
| 9 | Epidemic spreading and risk perception in multiplex networks :a self-organized percolation method显示文摘 | Massaro E Bagnoli F | 2014 | Physical Review E2014，90，5： | 1 |
| 10 | SSC radiation in BL Lacertae sources, the end of the tether 显示文摘 | Paggi A Massaro F Vittorini V | 2009 | Astronomy and Astrophysics2009，504，3： | 1 |
| 11 | Infrared colors of the gamma-ray-detected blazars 显示文摘 | D'Abrusco R Massaro F Ajello M | 2012 | The Astrophysical Journal2012，748，1： | 1 |
| 12 | Preparation and characterisation of titania/hydroxyapatite composite coatings obtained by sol–gel process显示文摘 | E Milella F Cosentino A Licciulli C Massaro | 2001 | Biomaterials2001，，： | 1 |
| 13 | Identification of the infrared non-thermal emission in blazars 显示文摘 | Massaro F D'Abrusco R Ajello M | 2011 | The Astrophysical Journal2011，740，2： | 1 |
| 14 | Searching for ',/-ray blazar candidates among the unidentified INTEGRAL sources 显示文摘 | Massaro F Paggi A D' Abrusco R | 2012 | The Astrophysical Journal Letters2012，750，2： | 1 |
| 15 | The wise gamma-ray strip parameterization: the nature of the gamma-ray active galactic nuclei of uncertain type 显示文摘 | Massaro F D'Abrnsco R Tosti G | 2012 | The Astrophysical Journal2012，750，2： | 1 |
| 16 | Epidemic spreading and riskperception in multiplex networks : A self-organized perco-lation method 显示文摘 | MASSARO E BAGNOLI F | 2014 | Physical Review E2014，90，05： | 1 |
| 17 | Induction of mitochondrial dysfunction and oxidative stress in human fibroblast cultures exposed to serum from septic patients 显示文摘 | Trentadue R Fiore F Massaro F | 2012 | Life Sci2012，91，78： | 1 |
| 18 | The concave X - ray spectrum of the Blazar ON 231 : The signature of intermediate BL Lac objects 显示文摘 | MASSARO E MAESANO M MONTAGNI F | 1999 | A&A1999，12，34： | 1 |
| 19 | Myelin basic protein and S 100 antigen in cerebrispinal fluid of pateins with multiple sclerosis in a cute phase显示文摘 | Massaro AR Michetti F Laudisio | 1985 | Ital J Neurol Sci1985，6，： | 1 |
| 20 | Procalcitonin (PCT) and C-reactive protein (CRP) as severe systemic infection markers in febrile neutropenic adults显示文摘 | MASSARO K S COSTA S F LEONE C | 2007 | BMC Infect Dis2007，7，： | 1 |
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