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| 1 | 地下水铀污染的原位微生物还原与固定:在美国能源部田纳西橡树岭放射物污染现场的试验显示文摘总结了美国斯坦福大学和橡树岭国家实验室等在美国能源部田纳西州橡树岭综合试验基地进行的铀污染原位微生物修复阶段性试验结果.本试验利用微生物以乙醇为电子供体还原地下水和沉积物中的六价铀为不溶解的四价铀,使之原位固定化.随后通过加入溶解氧和硝酸盐来试验微生物还原后的地下水层中还原固定态铀的稳定性.通过预处理和长期间隔注入乙醇溶液,地下水中铀浓度从40~60mg·L-1降至0.03mg·L-1以下,达到了美国环保署饮用水的标准.还原的四价铀主要以U(Ⅳ)-Fe复合物的形态存在.结果表明,固定化后的四价铀只有在厌氧条件下才是稳定的,溶解氧和硝酸盐侵入地下水层后会使固定化的四价铀重新氧化为溶解态的六价铀.在试验过程中,采用多种分子生物学方法检测了微生物种群的变化和与铀氧化还原反应有关的功能微生物.本研究表明,在维持试验系统无氧和无硝酸盐的条件下,通过添加乙醇为电子供体可有效地促进地下水中土著功能微生物的活性,从而实现铀的原位还原固定与稳定. | 吴唯民 Jack Carley David Watson 顾宝华 Scott Brooks Shelly D.Kelly Kenneth Kemner Joy D.van Nostrand 吴力游 许玫英 周集中 罗剑 Erick Cardenas 黄家琪 Matthew W.Fields Terence L.Marsh James M.Tiedje Stefan J.Green Joel E.Kostka Peter K.Kitanidis Philip M.Jardme CraigS.Criddle | 2011 | 环境科学学报2011，31，3： | 28 |
| 2 | Increased hepcidin expression in colorectal carcinogenesis显示文摘AIM:To investigate whether the iron stores regulator hepcidin is implicated in colon cancer-associated anae- mia and whether it might have a role in colorectal car- cinogenesis. METHODS: Mass spectrometry (MALDI-TOF MS and SELDI-TOF MS) was employed to measure hepcidin in urine collected from 56 patients with colorectal cancer. Quantitative Real Time RT-PCR was utilised to determine hepcidin mRNA expression in colorectal cancer tissue. Hepcidin cellular localisation was determined using im- munohistochemistry. RESULTS: We demonstrate that whilst urinary hepcidin expression was not correlated with anaemia it was posi- tively associated with increasing T-stage of colorectal cancer (P < 0.05). Furthermore, we report that hepcidin mRNA is expressed in 34% of colorectal cancer tissue specimens and was correlated with ferroportin repres- sion. This was supported by hepcidin immunoreactivity in colorectal cancer tissue. CONCLUSION: We demonstrate that systemic hepcidin expression is unlikely to be the cause of the systemic anaemia associated with colorectal cancer. However, we demonstrate for the first time that hepcidin is expressed by colorectal cancer tissue and that this may represent a novel oncogenic signalling mechanism. | Douglas G Ward Keith Roberts Matthew J Brookes Howard Joy Ashley Martin Tariq Ismail Robert Spychal Tariq Iqbal Chris Tselepis | 2008 | World Journal of Gastroenterology2008，14，9： | 12 |
| 3 | Moisture and temperature controls on nitrification differ among ammonia oxidizer communities from three alpine soil habitats显示文摘气候变化正在改变在许多 highelevation 生态系统预定和 biogeochemical 流动的大小。处于高山的氮的硝化作用率的作为结果的变化有潜力影响生态系统规模回答。为了更好理解变化温度和潮湿怎么调节,可以影响氨氧化剂和氮的硝化作用活动,我们在从三个高山的产地(冰川的冰川边碛外的沉积,距骨,和草地) 在一个科罗拉多分水岭收集的土壤上进行了实验室孵化。我们发现细菌,不是 archaea,统治了所有氨氧化剂社区。氮的硝化作用在所有土壤并且在所有温度处理下面与潮湿增加了。然而,温度没在所有土壤与氮的硝化作用率被相关。地点特定的温度趋势在土壤建议通晓各方面知识经验丰富的人氨 oxidzer 社区的发展与在在有更稳定的温度政体的土壤的 situ 温度变化和专家更大。很快增加的温度和变化土壤潮湿条件能在一些高山的土壤解释增加的硝酸盐生产的最近的观察。 | Brooke B. OSBORNE Jill S. BARON Matthew D. WALLENSTEIN | 2016 | Frontiers of Earth Science2016，10，1： | 8 |
| 4 | Effects of Allogeneic Red Blood Cell Transfusions on Clinical Outcomes in Patients Undergoing Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis显示文摘 | Austin G. Acheson Matthew J. Brookes Donat R. Spahn | 2012 | Annals of Surgery2012，，2： | 3 |
| 5 | Is iron overload in alcohol-related cirrhosis mediated by hepcidin?显示文摘In this case report we describe the relationship between ferritin levels and hepcidin in a patient with alcohol-related spur cell anemia who underwent liver transplantation.We demonstrate a reciprocal relation-ship between serum or urinary hepcidin and serum ferritin,which indicates that inadequate hepcidin production by the diseased liver is associated with elevated serum ferritin.The ferritin level falls with increasing hepcidin production after transplantation.Neither inflammatory indices(IL6)nor erythropoietin appear to be related to hepcidin expression in this case.We suggest that inappropriately low hepcidin production by the cirrhotic liver may contribute substantially to elevated tissue iron stores in cirrhosis and speculate that hepcidin replacement in these patients may be of therapeutic benefi t in the future. | Tariq Iqbal Azzam Diab Douglas G Ward Matthew J Brookes Chris Tselepis Jim Murray Elwyn Elias | 2009 | World Journal of Gastroenterology2009，15，46： | 2 |
| 6 | Emissive displays with transfer-printed assemblies of 8 μm × 15 μm inorganic light-emitting diodes显示文摘Displays using direct light emission from microscale inorganic light-emitting diodes(μILEDs)have the potential to be very bright and also very power efficient.High-throughput technologies that accurately and cost-effectively assemble microscale devices on display substrates with high yield are key enablers forμILED displays.Elastomer stamp transfer printing is such a candidate assembly technology.A variety ofμILED displays have been designed and fabricated by transfer printing,including passive-matrix and active-matrix displays on glass and plastic substrates. | CHRISTOPHER A.BOWER MATTHEW A.MEITL BROOK RAYMOND ERICH RADAUSCHER RONALD COK SALVATORE BONAFEDE DAVID GOMEZ TANYA MOORE CARL PREVATTE BRENT FISHER ROBERT ROTZOLL GEORGE A.MELNIK ALIN FECIORU ANTóNIO JOSé TRINDADE | 2017 | Photonics Research2017，5，2： | 2 |
| 7 | Habitat invisibility and dominance byalien annual plants in the western Mojave Desert显示文摘 | Matthew L Brooks M L | 1999 | BiologicalInvasions1999，1，： | 1 |
| 8 | Habitat invisibility and dominance byalien annual plants in the western Mojave Desert显示文摘 | Matthew L Brooks M L | 1999 | BiologicalInvasions1999，1，： | 1 |
| 9 | Risk Factors for Progression of Low-Grade Dysplasia in Patients With Barrett’s Esophagus显示文摘 | Sachin Wani Gary W. Falk Jane Post Lisa Yerian Matthew Hall Amy Wang Neil Gupta Srinivas Gaddam Mandeep Singh Vikas Singh Keng–Yu Chuang Vikram Boolchand Hemanth Gavini John Kuczynski Priti Sud Ajay Bansal Amit Rastogi Sharad C. Mathur Patrick Young Brook | 2011 | Gastroenterology2011，，4： | 1 |
| 10 | Ethnic differences in inflammatory bowel disease: Results from the United Kingdom inception cohort epidemiology study显示文摘BACKGROUND The current epidemiology of inflammatory bowel disease(IBD)in the multiethnic United Kingdom is unknown.The last incidence study in the United Kingdom was carried out over 20 years ago.AIM To describe the incidence and phenotype of IBD and distribution within ethnic groups.METHODS Adult patients(>16 years)with newly diagnosed IBD(fulfilling Copenhagen diagnostic criteria)were prospectively recruited over one year in 5 urban catchment areas with high South Asian population.Patient demographics,ethnic codes,disease phenotype(Montreal classification),disease activity and treatment within 3 months of diagnosis were recorded onto the Epicom database.RESULTS Across a population of 2271406 adults,339 adult patients were diagnosed with IBD over one year:218 with ulcerative colitis(UC,64.3%),115 with Crohn's disease(CD,33.9%)and 6 with IBD unclassified(1.8%).The crude incidence of IBD,UC and CD was 17.0/100000,11.3/100000 and 5.3/100000 respectively.The age adjusted incidence of IBD and UC were significantly higher in the Indian group(25.2/100000 and 20.5/100000)compared to White European(14.9/100000,P=0.009 and 8.2/100000,P<0.001)and Pakistani groups(14.9/100000,P=0.001 and 11.2/100000,P=0.007).The Indian group were significantly more likely to have extensive disease than White Europeans(52.7%vs 41.7%,P=0.031).There was no significant difference in time to diagnosis,disease activity and treatment.CONCLUSION This is the only prospective study to report the incidence of IBD in an ethnically diverse United Kingdom population.The Indian ethnic group showed the highest age-adjusted incidence of UC(20.5/100000).Further studies on dietary,microbial and metabolic factors that might explain these findings in UC are underway. | Ravi Misra Jimmy Limdi Rachel Cooney Samia Sakuma Matthew Brookes Edward Fogden Sanjeev Pattni Naveen Sharma Tariq Iqbal Pia Munkholm Johan Burisch Naila Arebi | 2019 | World Journal of Gastroenterology2019，25，40： | 1 |
| 11 | Patients With Nondysplastic Barrett’s Esophagus Have Low Risks for Developing Dysplasia or Esophageal Adenocarcinoma显示文摘 | Sachin Wani Gary Falk Matthew Hall Srinivas Gaddam Amy Wang Neil Gupta Mandeep Singh Vikas Singh Keng–Yu Chuang Vikram Boolchand Hemanth Gavini John Kuczynski Priti Sud Savio Reddymasu Ajay Bansal Amit Rastogi Sharad C. Mathur Patrick Young Brooks Cash Da | 2011 | Clinical Gastroenterology and Hepatology2011，，3： | 1 |
| 12 | Time Course of Inflammation, Myocardial Injury, and Prothrombotic Response After Radiofrequency Catheter Ablation for Atrial Fibrillation显示文摘 | Han S. Lim Carlee Schultz Jerry Dang Muayad Alasady Dennis H. Lau Anthony G. Brooks Christopher X. Wong Kurt C. Roberts-Thomson Glenn D. Young Matthew I. Worthley Prashanthan Sanders Scott R. Willoughby | 2014 | Circulation: Arrhythmia and Electrophysiology2014，，1： | 1 |
| 13 | Control of Invasive Weeds with Prescribed Burning 显示文摘 | Ditomaso Joseph M Brooks Matthew L Allen Edith B | 2006 | Weed Technology2006，20，2： | 1 |
| 14 | 未来氢能经济所需的铂资源是否充足(英文/中文)显示文摘对于未来氢能和燃料电池行业对铂金需求量的分析,市场人士的各种预测不尽相同。但是,我们相信即使在该行业出现了一个高增长的情况下,铂金的供应量也足以满足未来十年乃至更长时间的需求。 | David JOLLIE Matthew TURNER Dawn BROOKS | 2020 | 贵金属2020，41，S01： | 1 |
| 15 | Effect of Atrial Fibrillation on Atrial Thrombogenesis in Humans: Impact of Rate and Rhythm显示文摘 | Han S. Lim Scott R. Willoughby Carlee Schultz Cheryl Gan Muayad Alasady Dennis H. Lau Darryl P. Leong Anthony G. Brooks Glenn D. Young Peter M. Kistler Jonathan M. Kalman Matthew I. Worthley Prashanthan Sanders | 2013 | Journal of the American College of Cardiology2013，，8： | 1 |
| 16 | Cellular Markers of Muscle Atrophy in Chronic Obstructive Pulmonary Disease显示文摘 | Plant Pamela J Brooks Dina Faughnan Marie Bayley Tanya Bain James Singer Lianne Correa Judy Pearce Dawn Binnie Matthew Batt Jane | 2010 | American Journal of Respiratory Cell and Molecular Biology2010，，4： | 1 |
| 17 | Risk Factors for Progression of Low-Grade Dysplasia in Patients With Barrett’s Esophagus显示文摘 | Sachin Wani Gary W. Falk Jane Post Lisa Yerian Matthew Hall Amy Wang Neil Gupta Srinivas Gaddam Mandeep Singh Vikas Singh Keng–Yu Chuang Vikram Boolchand Hemanth Gavini John Kuczynski Priti Sud Ajay Bansal Amit Rastogi Sharad C. Mathur Patrick Young Brook | 2011 | Gastroenterology2011，，4： | 1 |
| 18 | Patients With Nondysplastic Barrett’s Esophagus Have Low Risks for Developing Dysplasia or Esophageal Adenocarcinoma显示文摘 | Sachin Wani Gary Falk Matthew Hall Srinivas Gaddam Amy Wang Neil Gupta Mandeep Singh Vikas Singh Keng–Yu Chuang Vikram Boolchand Hemanth Gavini John Kuczynski Priti Sud Savio Reddymasu Ajay Bansal Amit Rastogi Sharad C. Mathur Patrick Young Brooks Cash Da | 2011 | Clinical Gastroenterology and Hepatology2011，，3： | 1 |
| 19 | Anti-inflammatory effects of PPAR-γ agonists directly correlate with PPAR-γ expression during acute pancreatitis显示文摘 | Michael D. Rollins M.D. Sharon Sudarshan M.D. Matthew A. Firpo Ph.D. Brooke H. Etherington M.D. Brandon J. Hart M.D. Heidi H. Jackson M.D. Jeffrey D. Jackson M.D. Lyska L. Emerson M.D. David T. Yang M.D. Sean J. Mulvihill M.D. Robert E. Glasgow M.D | 2006 | Journal of Gastrointestinal Surgery2006，，8： | 1 |
| 20 | On the detection of clones in sensor networks using random key predistribution显示文摘 | BROOKS Richard GOVINDARAJU P Y PIRRETTI Matthew | 2007 | IEEE Transactions on Systems Man and Cybernetics: Part C2007，37，6： | 1 |
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