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您的检索式：作者名="Matthias PA"
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| 1 | A new endophytic insect-associated Daldinia species, recognised from a comparison of secondary metabolite profiles and molecular phylogeny显示文摘Xylariaceous endophytes are commonly encountered in plants,and it has recently been found out that insect vectors play a major role in their life cycle,as well as in the apparent host-specificity of the fungal stromata.In this study,a new insect-associated,endophytic anamorph species of Daldinia is recognised from a comparison of (a)morphological and ecological data;(b)molecular phylogenetic data based on rDNA,alpha-actin and beta-tubulin genes;and (c)secondary metabolite profiles based on high performance liquid chromatography/diode array/mass spectrometry(HPLC-DAD/MS)and gas chromatography/mass spectrometry(GC-MS)in comparison with authentic strains of Daldinia and other Xylariaceae.The new species,Daldinia hawksworthii,is a symbiont of the willow woodwasp,Xiphydria prolongata,which is in turn preferentially associated with Salix.A comparison of HPLCDAD/MS profiles from standardised cultures revealed the presence of a specific compound,which was not encountered in any of the ca.250 Daldinia strains studied for comparison.This compound was isolated after fermentation of the fungus in 10 l scale by preparative chromatography.Structure elucidation by NMR spectroscopy revealed a novel pyrone,for which the name dalsymbiopyrone is proposed.The compound showed weak antimicrobial and cytotoxic effects and might be a signal molecule involved in the trilateral ecological interaction between the host plant,the insect,and its fungal symbiont. | Sylvie Pažoutová Stefanie Follert Jens Bitzer Matthias Keck Frank Surup PetrŠrůtka Jaroslav Holuša Marc Stadler | 2013 | Fungal Diversity2013，，3： | 1 |
| 2 | Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers显示文摘 | Matthias PA Suzanne HM Lori Tonnes | 2005 | Neoplasia2005，7，8： | 1 |
| 3 | Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal canaers显示文摘 | Matthias PA Ebert W Suzanne H | 2005 | Neoplasia2005，7，： | 1 |
| 4 | Increased β-catenin mRNA levels and mutational alterations of the APC and β-catenin gene are present in intestinaltype gastric cancer显示文摘 | Matthias PA Ebert Guo Fei Sabine Kahmann | 2002 | Carcinogenesis2002，23，1： | 1 |
| 5 | Loss of Beta-catenin expression in metastatic gastric cancer 显示文摘 | Matthias PA Ebert Jun Yu Juliane Hoffmann | 2003 | J Clin Oncol2003，21，9： | 1 |
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