|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Aerobic bacteria associated with chronic suppurative otitis media in Angola显示文摘Background:Chronic suppurative otitis media(CSOM)is an important cause of hearing loss in children and constitutes a serious health problem globally with a strong association to resource-limited living conditions.Topical antibiotics combined with aural toilet is the first-hand treatment for CSOM but antimicrobial resistance and limited availability to antibiotics are obstacles in some areas.The goal of this study was to define aerobic pathogens associated with CSOM in Angola with the overall aim to provide a background for local treatment recommendations.Methods:Samples from ear discharge and the nasopharynx were collected and cultured from 152 patients with ear discharge and perforation of the tympanic membrane.Identification of bacterial species was performed with matrix-assisted laser desorption/ionization-time of flight mass spectrometry and pneumococci were serotyped using multiplex polymerase chain reactions.Antimicrobial susceptibility testing was done according to EUCAST.Results:One hundred eighty-four samples from ear discharge and 151 nasopharyngeal swabs were collected and yielded 534 and 289 individual isolates,respectively.In all patients,correspondence rate of isolates from 2 ears in patients with bilateral disease was 27.3%and 9.3%comparing isolates from the nasopharynx and ear discharge,respectively.Proteus spp.(14.7%),Pseudomonas aeruginosa(13.2%)and Enterococcus spp.(8.8%)were dominating pathogens isolated from ear discharge.A large part of the remaining species belonged to Enterobacteriaceae(23.5%).Pneumococci and Staphylococcus aureus were detected in approximately 10%of nasopharyngeal samples.Resistance rates to quinolones exceeded 10%among Enterobacteriaceae and was 30.8%in S.aureus,whereas 6.3%of P.aeruginosa were resistant.Conclusions:The infection of the middle ear in CSOM is highly polymicrobial,and isolates found in nasopharynx do not correspond well with those found in ear discharge.Pathogens associated with CSOM in Angola are dominated by gram-negatives including Enterobacteriaceae and P.aeruginosa,while gram-positive enterococci also are common.Based on the results of antimicrobial susceptibility testing topical quinolones would be the preferred antibiotic therapy of CSOM in Angola.Topical antiseptics such as aluminium acetate,acetic acid or boric acid,however,may be more feasible options due to a possibly emerging antimicrobial resistance. | Fabian Udden Matuba Filipe Ake Reimer Maria Paul Erika Matuschek John Thegerstrom Sven Hammerschmidt Tuula Pelkonen Kristian Riesbeck | 2018 | Infectious Diseases of Poverty2018，7，1： | 6 |
| 2 | 查看详情显示文摘 | Becker L Lenoir D Matuschek G | | 0，，： | 1 |
| 3 | Thermal stability and degradation of starch derivatives显示文摘 | Rudnik E Matuschek G Milanov N | 2006 | J Therm Anal Calorim2006，85，2： | 1 |
| 4 | Exact coupled-mode theories for multilayer interference coatings with arbitrary strong index modulations显示文摘 | Matuschek N Kartner F X Keller U | | 0，，03： | 1 |
| 5 | Exact coupled-mode theories for multilayer interference coatings with arbitrary strong index modulations显示文摘 | Matuschek N Kartner F X Keller U | 1997 | IEEE Journal of Quantum Electronics1997，33，3： | 1 |
| 6 | Lifetime simulation and thermal characterization of PVC cable insulation materials显示文摘 | Benes M Placek V Matuschek G | 2005 | Journal of Thermal Analysis and Calorimetry2005，82，： | 1 |
| 7 | Thermal properties of starch succinates显示文摘 | Matuschek G Milanov N | 2005 | Thermochimica Acta2005，427，： | 1 |
| 8 | Theory of double-chirped mirrors显示文摘 | Matuschek N Kartner F X Keller U | 1998 | IEEE Journal of Selected Topics in Quantum Electronics1998，4，2： | 1 |
| 9 | Main products and kinetics of the thermal degradation of polyamides 显示文摘 | Herrera M Matuschek G Kettrup A | 2001 | Chemosphere2001，42，： | 1 |
| 10 | 查看详情显示文摘 | Herrera M Matuschek G Kettrup A | | 0，，： | 1 |
| 11 | Analytical design of double-chirped mirrors with custom-tailored dispersion characteristics显示文摘 | Matuschek N Kartner F X Keller U | 1999 | IEEE Journal of Quantum Electronics1999，35，2： | 1 |
| 12 | Fermentation and Enzyme Treatment of Tannin Sorghum Gruels: Effects on Phenolic Compounds, Phytate and in Vitro Accessible Iron 显示文摘 | Towo E Matuschek E Svanberg U | 2006 | Food Chemistry2006，94，3： | 1 |
| 13 | Bevacizumab as a treatment option for radiation-induced cerebral necrosis显示文摘 | Matuschek C Bolke E Nawatny J | 2011 | Strahlenther Onkol2011，187，2： | 1 |
| 14 | OC-0149:Adjuvant radiotherapy of regional lymph nodes in breast cancer-a meta-analysis of randomized trials显示文摘 | Matuschek C Kammers K Boelke E | 2014 | Radiat Oncol2014，111，1： | 1 |
| 15 | Inhibitory effects of rat bone marrow-derived dendritic cells on naive and alloantigen specific CD4^+ T cells: a comparison between dendritic ceils generated with GM-CSF plus IL-4 and dendritic cells generated with GM CSF plus IL 10显示文摘 | Tiurb G Matuschek A Kammerer U | 2009 | BMC Res Notes2009，2，1： | 1 |
| 16 | Theory of double-chirped mirrors 显示文摘 | MATUSCHEK N KARTNER F X KELLER U | 1998 | Journal of Selected Topics Quantum Electron IEEE1998，4，2： | 1 |
| 17 | Methylated APC and GSTP1 genes in serum DNA correlate with the presence of circulating blood tumor cells and are associated with a more aggressive and advanced breast cancer disease显示文摘 | Matuschek C B(o)lke E Lammering G | 2010 | Eur J Med Res2010，15，： | 1 |
| 18 | RASSF1A proteinexpression and correlation with clinicopathological parameters inrenal cell carcinoma显示文摘 | Tezval H Merseburger AS Matuschek I | 2008 | BMC Urol2008，8，12： | 1 |
| 19 | The jejunum is the main site of absorption for anthocyanins in mice显示文摘 | Matuschek MC HendriksWH McGhie TK | | 0，，： | 1 |
| 20 | Exact coupled-mode theories for multilayer interference coatings with arbitrary strong index modulations显示文摘 | MATUSCHEK N KARTNER F X KELLER U | 1997 | IEEE Journal of Quantum Electronics1997，33，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员