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38篇 您的检索式:作者名="Mazzella G"
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1Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients显示文摘AIM: To simultaneously evaluate the presence of defects in gallbladder and gastric emptying, as well as in intestinal transit in gallstone patients (GS) and the effect of chronic ursodeoxycholic acid (UDCA) administration on these parameters and on serum bile acids and clinical outcome in GS and controls (CTR). METHODS: After a standard liquid test meal, gallbla-dder and gastric emptying (by ultrasound), oroileal transit time (OITT) (by an immunoenzymatic technique) and serum bile acids (by HPLC) were evaluated before and after 3 mo of UDCA (12 mg/kg bw/d) or placebo administration in 10 symptomatic GS and 10 matched healthy CTR. RESULTS: OITT was longer in GS than in CTR (P < 0.0001); UDCA significantly reduced OITT in GS (P < 0.0001), but not in CTR. GS had longer gastric half-emptying time (t1/2) than CTR (P < 0.0044) at baseline; after UDCA, t1/2 significantly decreased (P < 0.006) in GS but not in CTR. Placebo administration had no effect on gastric emptying and intestinal transit in both GS and CTR. CONCLUSION: The gallstone patient has simultaneous multiple impairments of gallbladder and gastric emptying, as well as of intestinal transit. UDCA administration restores these defects in GS, without any effect in CTR. These results confirm the pathogenetic role of gastrointestinal motility in gallstone disease and suggest an additional mechanism of action for UDCA in reducing bile cholesterol supersaturation.A Colecchia G Mazzella L Sandri F Azzaroli M Magliuolo P Simoni ML Bacchi-Reggiani E Roda D Festi 2006World Journal of Gastroenterology2006,12,33:4
2Ursodeoxycholic acid administration in patients with cholestasis of pregnancy:effects on primary bile acids in babies and mothers显示文摘Mazzella G Rizzo N Azzaroli F 2001Heptology2001,33,:1
3Ursodeoxycholic acid administration in patients with cholestasis of pregnancy : effects on primary bile acids in babies and mothers显示文摘Mazzella G Rizzo N Azzaroli F 2001Hepatology2001,33,3:1
4Urs0de0xych0lic acid ad- ministration in patients with cholestasis of pregnancy : elects on primary bile acids in babies and mothers显示文摘Mazzella G Rizzo N Azzaroli F 2001Hepatology2001,33,3:1
5Rifaximin in the treatment of chronic hepatic encephalopathy ? resultes of a multicenter study of efficacy and safety显示文摘Festi D Mazzella G Orsini M 1993Current Therapeutic Research1993,54,5:1
6Long-term results with interferon therapy in chronic type B hepatitis:A prospective randomized trial显示文摘Mazzella G Saracco G Festi D 1999Am J Gastroenterol1999,94,8:1
7Safety of interferon beta treatment for chronic HCV hepatitis 显示文摘Festi D Sandri L Mazzella G 2004World J Gastroenterol2004,10,:1
8Acquired gallstone opacification during cholelitholytic treatment with chenodeoxyholic,ursodeoxycholic,and tauroursodeoxycholic acids显示文摘Bazzoli F Festi D Mazzella G 1995The American journal of gastroenterology1995,90,6:1
9Ursodeoxycholic acid administration in patients with cholestasis of pregnancy:effects on primary bile acid in babies and mothers显示文摘Mazzella G Nicola R Francesco A 2001Hepatology2001,33,3:1
10Sluggish small bowel motility is involved in determining increased biliary deoxycholic acid in cholesterol gallstone patients显示文摘 Mazzella G Mazzeo C 1999Am J Gastroenterol1999,94,9:1
11Long-term results with interferon therapy in chronic type B hepatitis: a prospective randomized trial显示文摘Mazzella G Saracco G Festi D 1999Am J Gastroenterol1999,94,8:1
12Ursodeoxycholic acid ad ministration in pacients with cholestasis of pregnancy:effects on pri mary bile acids in babies and mothers 显示文摘Mazzella G Rizzo N Azzaroli F 2001Hepatology2001,33,:1
13Ursodexycholic acid administration in patients with cholestasis of pregnancy:effects on primary bile acids in babies and mothers显示文摘MAZZELLA G NICOLA R FRANCESCO A 2001Hepatology2001,33,:1
14Safety of interferon beta treatment for chronic HCV hepatitis显示文摘Festi D Sandri L Mazzella G 2004World J Gastroenterol2004,10,1:1
15Ursodcoxycholic acid administration in patient with cholestasis of pregnancy:effects on primary bile acids in babies and mothers显示文摘Mazzella G Rizzo N Azzaroli F 2001Hepatology2001,33,3:1
16Ursodeoxycholic acid administra tion in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers 显示文摘Mazzella G Rizzo N Azzaroli F 2001Hepatology2001,33,3:1
17Ursodexycholic acid administration in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers显示文摘Mazzella G Nicola R Francesco A 2001Hepatology2001,33,:1
18Ursodexy cholic acid administration in patients with cholestasis of pregnancy : effects on primary bile acid in babies and mothers 显示文摘Mazzella G Nicola R Francesco A 2001Hepatology2001,33,3:1
19Ursodexycholic acid administration in patients with cholestasis of pregnancy:effects on primary bile acid in babies and mothers显示文摘 Nicola R Francesco A 2001Hepatology2001,33,3:1
20查看详情显示文摘Tuteja A Choi W Ma M Mabry J M Mazzella S A Rutledge G C McKinley G H Cohen R E 0,,:1
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