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| 1 | Gene alterations in the PI3K/PTEN/AKT pathway as a mechanism of drug-resistance(Review)显示文摘 | Sameh Hafsi Franca Pezzino Saverio Candido Giovanni Ligresti Demetrios Spandidos Zohra Soua James McCubrey Salvatore Travali Massimo Libra | 2012 | International Journal of Oncology2012，，3： | 4 |
| 2 | Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance显示文摘 | James A. McCubrey Linda S. Steelman William H. Chappell Stephen L. Abrams Ellis W.T. Wong Fumin Chang Brian Lehmann David M. Terrian Michele Milella Agostino Tafuri Franca Stivala Massimo Libra Jorg Basecke Camilla Evangelisti Alberto M. Martelli Richard | 2006 | BBA - Molecular Cell Research2006，，8： | 3 |
| 3 | Reactive oxygen species-induced activation of the MAP kinase signaling pathways显示文摘 | McCubrey J A Lahair M M Franklin R A | 2006 | Antioxid Redox Signal2006，8，910： | 1 |
| 4 | The raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia 显示文摘 | Lee JTJr McCubrey JA | 2002 | Leukemia2002，16，4： | 1 |
| 5 | Roles of the Raf/MEK/ERKpathway in cell growth,malignant transformation and drug resistance显示文摘 | McCubrey JA Steelman LS Chappell WH | | 0，，08： | 1 |
| 6 | Targeting survival cas- cades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/ Akt/ mTOR and Jak/STAT pathways for effective leukemia therapy 显示文摘 | McCubrey JA Steelnmn LS Abrams SL | 2008 | Leukemia2008，22，4： | 1 |
| 7 | Current treatment strate- gies for inhibiting mTOR in cancer显示文摘 | Chiarini F Evangelisti C McCubrey JA | 2015 | Trends Pharmacol Sci2015，36，2： | 1 |
| 8 | The role ofdownstream signaling pathways of the epidermal growth fac-tor receptor for Artesunate's activity in cancer cells显示文摘 | Konkimalla VB McCubrey JA Efferth T | 2009 | Curr Cancer Drug Targets2009，9，： | 1 |
| 9 | Raf-induced cell cy-cle progression in human tf-1 hematopoietic cells显示文摘 | Chang F Steelman L S McCubrey J A | 2002 | Cell Cy-cle2002，1，： | 1 |
| 10 | Ras/Raf/ MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to over- come resistance显示文摘 | McCubrey J A Steelman L S Chappell W H | 2012 | Oncotarget2012，3，10： | 1 |
| 11 | The Raf/Mek/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia显示文摘 | Lee JT McCubrey JA | 2002 | Leukemia2002，16，： | 1 |
| 12 | Roles, of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance 显示文摘 | McCubrey J A Steelman L S Chappell W H | 2007 | Biochim Biophys Acta2007，1773，8： | 1 |
| 13 | Redox regulation of the calcium/calmodulin-dependent protein kinases显示文摘 | Howe C J LaHair MM McCubrey JA | 2004 | J Biol Chem2004，279，44： | 1 |
| 14 | Roles of the Raf/MEK /ERK pathway in cell growth,malignant transformation and drug resistance显示文摘 | McCubrey JA Steelman LS Chappell WH | 2007 | Biochim Biophys Acta2007，1773，8： | 1 |
| 15 | A Dominant Role for p53-de-pen- dent cellular senescence in radiosensitization of human prostate cancer cells显示文摘 | Lehmann BD McCubrey JA | 2007 | Cell Cycle2007，6，5： | 1 |
| 16 | Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance 显示文摘 | McCubrey JA Abrams SL Ligresti G | 2008 | Leukemia2008，22，11： | 1 |
| 17 | Pancreatic cancer stem ceils: Association with cell surface markers, prognosis, resistance, metastasis and treatment显示文摘 | Fitzgerald TL McCubrey JA | 2014 | Adv Biol Regul2014，56，： | 1 |
| 18 | Interactions be- tween the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells显示文摘 | McCubrey JA Lee JT Steelman LS | 2001 | Cancer Detect Prev2001，25，： | 1 |
| 19 | Kinases:positive and negative regulators of apoptosis显示文摘 | Franklin R A McCubrey J A | 2000 | Leukemia2000，14，12： | 1 |
| 20 | Roles of the Raf/MEK/ERK pathway in cell growth, malign ant, transforma- tion and drug resistance 显示文摘 | McCubrey J A Steelman L S Chappell W H | 2007 | Biochim Biophys Acta2007，1773，8： | 1 |
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