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您的检索式：作者名="Md.Saiful Hoque"
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| 1 | Flexural Strength and Load-Deflection Behaviour of Hybrid Thermoset Composites of Wood and Canola Biopolymers显示文摘The study aims to incorporate cellulosic canola(Brassica napus L.)biopolymers with wood biomass to increase flexural strength more than wood fraction alone.A facile fabrication process-at ambient temperature-is employed for ease of producing two different sets of bio-composites utilizing unsaturated polyester resin:pristine composite structures of 100%wood and hybrid composite structures of a canola-wood blend.The curing process is accompanied by methyl ethyl ketone peroxide(MEKP).Besides the lightweight feature,the hybrid composite structures exhibit maximum flexural strength up to 59.6 and 89.58 MPa at 2.5 and 5%fibre polymer fraction,outperforming the pristine wood composites(49.25 MPa).Also,the bending behaviours of the composite structures are illustrated by the load-deflection curves and the associated SEM micrographs display their fractured and debonded surface at the cross-section.The novel canola fibre benefits from its inherent hollow architecture,facilitating an excellent strength to weight ratio for the thermoset composites.Interestingly,canola displays a fibre diameter and density of 79.80(±41.31)μm and 1.34(±0.0014)g/cc,contributing effectively towards the flexure performance and high packing density.The breaking tenacity(13.31±4.59 g-force/tex)and tensile strength(174.93±60.29)of canola fibres are comparable to other bast fibres.The synergy among fibre diameters,density and break-ing tenacity creates a good interphase to successfully transfer the external compressive load from the resin matrix to the fibres.Further,the two-parameter Weibull distribution model is applied for predicting the failure and reliability probability of composite specimens against a wide range of compressive loads.Finally,prioritized SWOT factors have been summa-rized associated with the prospects and key challenges of canola biopolymers-an attempt to strategize the planning and decision-making process for a potential business environment.The introduction of canola into the plastic industries would ultimately promote the application of sustainable biopolymers in diverse grounds including the interior panels for aerospace,automotive,and furniture industries. | Ikra Iftekhar Shuvo Md.Saiful Hoque Md.Shadhin Lovely K.M.Khandakar | 2021 | Advanced Fiber Materials2021，3，5： | 0 |
| 2 | Curculigo recurvata W.T.Aiton exhibits anti-nociceptive and anti-diarrheal effects in Albino mice and an in silico model显示文摘Background: Curculigo recurvata(C. recurvata) is an enthnomedicinally important herb reported to have significant medicinal values. The present study aimed to explore the in vivo and in silico anti-nociceptive and anti-diarrheal effects of a C. recurvate rhizome methanol extract(Me-RCR).Methods: The analgesic effects of Me-RCR were assessed using acetic acid-induced writhing and the formalin-induced flicking test. The drugs were administered intraperitoneally(IP) at doses of 200 and 400 mg/kg body weight(bw). Anti-diarrheal activity was evaluated by assessing intestinal motility, hypersecretion, and fecal score in mice at oral doses of 200 and 400 mg/kg·bw. Computer facilitated analyses for anti-nociceptive and anti-diarrheal activities of three isolated compounds from C. recurvata were undertaken to identify the best-fit phytoconstituents.Results: The Me-RCR showed significant(P <.05) peripheral anti-nociception at the highest dose. The extract inhibited both early and late phases of nociception in the formalin-induced writhing test. In the castor oil-induced diarrhoea model, the extract significantly(P <.05) prolonged the onset time of diarrhoea, inhibited percentage of diarrhoea, and decreased both the volume and weight of intestinal contents. Rates of intestinal fluid accumulation inhibition were(33.61 ± 1.00)% and(46.44 ± 0.89)% at Me-RCR doses of 200 and 400 mg/kg·bw, respectively. Moreover, a significant(P <.05) reduction in gastrointestinal motility was observed. An absorption, distribution, metabolism, excretion and/or toxicity(ADME/T) test showed that the selected compounds yielded promising results, satisfying Lipinski's rule of five for predicting drug-like potential. Notably, of the three phytoconstituents curculigine and isocurculigine possessed the highest affinity for the COX-1 and COX-2. Isocurculigine was also identified as the most effective anti-diarrheal compound in the computer-facilitated model.Conclusion: An extract of the plant C. recurvata showed potential analgesic and antidiarrheal activity due to the presence of one or more active secondary metabolite(s). | Shabbir Ahmad Mst.Samima Nasrin A.S.M.Ali Reza Nishan Chakrabarty Md.Akramul Hoque Sanjida Islam Mohammad Shah Hafez Kabir Syed Mohammed Tareq A.H.M.Khurshid Alam Md.Areeful Haque Md.Saiful Islam Arman | 2020 | Animal Models and Experimental Medicine2020，3，2： | 0 |
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