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| 1 | Hepatoprotective activity of Terminalia paniculata against paracetamol induced hepatocellular damage in Wistar albino rats显示文摘Objective:To evaluate the hepatoprotective activity of Terminalia paniculata against paracetamol induced hepatic damage in rats.Methods:The plant material was shade dried, powdered and extracted with ethanol.Liv 52 and silymarin were used as standard drugs and 2%gum acacia as a control(vehicle).Alteration in the levels of biochemical markers of hepatic damage like AST,ALT,ALP and lipid peroxides were tested,and phytochemical tests were also performed.Results:Paracetamol(2 g/kg) increased the serum levels of alanine aminotransfer (ALT),aspartate aminotransferase(AST),alkaline phosphatase(ALP) and the lipid peroxides. Treatment of Liv 52,silymarin and ethanolic extract of Terminalia paniculata(200 mg/kg) altered levels of biochemical marker and showed significant hepatoprotective activity.Ethanolic extract revealed the presence of phenolic compound and flavanoids.Our findings suggested that ethanolic bark extract of Terminalia paniculata possessed hepatoprotective activity in a dose dependent manner.Conclusions:Terminalia paniculata possesses hepatoprotective activity.It could be an effective and promising preventive agent against PCT induced hepatotoxicity. | Eesha BR Mohanbabu Amberkar V Meena Kumari K Sarath babu Vijay M Lalit M Rajput R | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，6： | 5 |
| 2 | Synthesis, biological evaluation and molecular docking study of novel piperidine and piperazine derivatives as multi- targeted agents to treat Alzheimer disease显示文摘 | Meena P Nenmysh V Khatri M | 2015 | Bioorg Med Chem2015，23，5： | 1 |
| 3 | Multifunctional novel Diallyl disulfide (DADS) derivatives with beta- amyloid-reducing, cholinergie, antioxidant and metal chelating properties for the treatment of Alzheimer 's disease显示文摘 | Manral A Saini V Meena P | 2015 | Bioorg Med Chem2015，23，19： | 1 |
| 4 | Synthe- sis,analgesic,anti-inflammatory, ulcerogenic index and antibacte- rial activities of novel 2-methylthio-3-substituted-5,6,7,8-tetra hydrobenzo (b) t hieno显示文摘 | ALAGARSAMY V MEENA S RAMSESHU K V | 2006 | Europe- an Journal of Medicinal Chemistry2006，，： | 1 |
| 5 | Effect of negative air ions on fog and smoke 显示文摘 | Sawant V S Meena G S Jadhav D B | 2012 | Aerosol and Air Quality Research2012，，12： | 1 |
| 6 | Myasthenic crisis: clinical features, complications and mortality 显示文摘 | Murthy J M Meena A K Chowdary G V | 2005 | Neurol India2005，53，1： | 1 |
| 7 | Synthesis,analgesic,anti-inflammatory,ulcerogenic index and antibacterial activities of novel 2-methylthio-3-substituted-5,6,7,8-tetrahydrobenzo(b)thienopyrimidin-4(3 H)-ones显示文摘 | ALAGARSAMY V MEENA S RAMSESHU K V | 2006 | Eur J Med Chem2006，41，11： | 1 |
| 8 | Decompressive cranieetomy for stroke: indications and results显示文摘 | Reddy AK Saradhi V Panigrahi M Rao TN Tripathi P Meena AK | 2002 | Neurol India2002，50，1： | 1 |
| 9 | Prevalence of antithyroid peroxidase anti-bodies in pregnant women and the effect on the outcome of pregnancy显示文摘 | Meena M Chopra S Jain V | 2014 | Obstet Gynecol2014，123，1： | 1 |
| 10 | Chemistry and biology of thyrotropin-releasing hormone (TRH) and its analogs 显示文摘 | Monga V Meena CL Kaur N | 2008 | Curr Med Chem2008，15，26： | 1 |
| 11 | Demonstration of redox potential of Metschnikowia koreensis for stereoinversion of secondary alcohols/1,2-diols显示文摘 | MEENA V S BANOTH L BANERJEE U C | 2014 | BioMed Research International2014，2014，41： | 1 |
| 12 | Causality of injury and outcome inpatients admitted in a major trauma center in North India显示文摘 | Rastogi D Meena S Sharma V | 2014 | Int J Crit Illn Inj Sci2014，4，4： | 1 |
| 13 | Ochronotic black meniscus dur- ing knee arthroscopy 显示文摘 | Nag HL Singh V Meena S | 2013 | J Nat Sci Biol Med2013，4，2： | 1 |
| 14 | Association of TLR5gene polymorphisms in ulcerative colitis patients of north India and their role in cytokine homeostasis显示文摘 | Meena NK Ahuja V Meena K | 2015 | PLoS One2015，10，01： | 1 |
| 15 | Synthesis,analgesic,anti-inflammatory,ulcerogenic index andantibacterial activities of novel 2-methylthio-3-substituted-5,6,7,8-tetrahydrobenzo(b)thienopyrimidin-4(3H)-ones显示文摘 | Alagarsamy V Meena S Ramseshu K V | 2006 | Eur J Med Chem2006，41，11： | 1 |
| 16 | Association of TLR5 Gene Polymorphisms in Ulcerative Colitis Patients of North India and Their Role in Cytokine Homeostasis 显示文摘 | Meena NK Ahuja V Meena K | 2015 | PLoS One2015，10，01： | 1 |
| 17 | Correlation of Brain Bio- marker Neuron Specific Enolase (NSE) with Degree of Disability and Neurological Worsening in Cerebmvascular Stroke 显示文摘 | Anuradha B Vivek VB Meena V | 2012 | Indian Journal of Clinical Biochemistry2012，27，2： | 1 |
| 18 | Association of TLR5 gene polymorphisms in ulcerative colitis patients of north India and their role in cytokine homeostasis 显示文摘 | MEENA NK AHUJA V MEENA K | 2015 | PLoS One2015，10，01： | 1 |
| 19 | A genome-wide association study of aging显示文摘 | Stefan Walter Gil Atzmon Ellen W. Demerath Melissa E. Garcia Robert C. Kaplan Meena Kumari Kathryn L. Lunetta Yuri Milaneschi Toshiko Tanaka Gregory J. Tranah Uwe V?lker Lei Yu Alice Arnold Emelia J. Benjamin Reiner Biffar Aron S. Buchman Eric Boerwinkle | 2011 | Neurobiology of Aging2011，，11： | 1 |
| 20 | Design and synthesis of 2-methylthio-3-substituted-5, 6-dimethylthieno pyrimidin-4(3H)-ones as analgesic,anti-inflam- matory and antibacterial agents显示文摘 | Alagarsamy V Solomon V R Meena R | 2007 | Med Chem2007，3，1： | 1 |
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