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您的检索式：作者名="Megan Barnes"
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| 1 | 儿童用药临床研究迫在眉睫显示文摘儿科更容易发生医疗差错,因为按照年龄和体重计算剂量的治疗指南通常不适用于儿童。一直以来,都认为在儿童中进行临床研究是不符合伦理道德的,甚至是没必要的。目前,用于儿科患者的药物有2/3以上没进行过临床研究。但是,越来越多的儿童患上了以前认为只有成年人才会患的疾病,之前只用于成年人的药物,现在也越来越多的用于儿童,比如抗糖尿病药物、抗高血压药物、降脂药物、精神类药物以及用于咳嗽和感冒的药物。所以自上世纪90年代以后,在儿童患者中进行临床研究的需要变得越来越迫切。 | Kelly Dowhower Karpa Megan Barnes 梁伟 | 2008 | 中国处方药2008，7，4： | 2 |
| 2 | Effectiveness of terrestrial protected areas in reducing habitat loss and population declines显示文摘 | Jonas Geldmann Megan Barnes Lauren Coad Ian D. Craigie Marc Hockings Neil D. Burgess | 2013 | Biological Conservation2013，，： | 1 |
| 3 | Evaluation of neuromuscular electronic stimulation on dysphagia显示文摘 | Larry Barnes Megan Miller Neal S | 2008 | J Clin Eng2008，3，20： | 1 |
| 4 | Correlation of rapid point-of-care vs send-out fecal calprotectin monitoring in pediatric inflammatory bowel disease显示文摘AIM To assess the correlation between the send-out enzymelinked immuno sorbent assay(ELISA) and the point-ofcare(POC) calprotectin test in pediatric inflammatory bowel disease(IBD) patients.METHODS We prospectively collected stool samples in pediatric IBD patients for concomitant send-out ELISA analysis and POC calprotectin testing using the Quantum Blue?(QB) Extended immunoassay. Continuous results between 17 to 1000 μg/g were considered for comparison. Agreement between the two tests was measured by a Bland-Altman plot and statistical significance was determined using Pitman's test.RESULTS Forty-nine stool samples were collected from 31 pediatric IBD patients. The overall means for the rapid and ELISA tests were 580.5 and 522.87 μg/g respectively. Among the 49 samples, 18(37.5%) had POC calprotectin levelsof ≤ 250 μg/g and 31(62.5%) had levels > 250 μg/g.Calprotectin levels ≤ 250 μg/g show good correlation between the two assays. Less correlation was observed at quantitatively higher calprotectin levels. CONCLUSION In pediatric IBD patients, there is better correlation of between ELISA and POC calprotectin measurements at clinically meaningful, low-range levels. Future adoption of POC calprotectin testing in the United States may have utility for guiding clinical decision making in real time. | Alexis Rodriguez Lauren Yokomizo Megan Christofferson Danielle Barnes Nasim Khavari KT Park | 2017 | World Journal of Gastrointestinal Pharmacology and Therapeutics2017，8，2： | 1 |
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