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86篇 您的检索式：作者名="Melzer J"

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	题名	作者	年代	出处	被引量
1	Reduced striatal volumes in Parkinson’s disease:a magnetic resonance imaging study显示文摘Background:The presence and extent of structural changes in the brain as a consequence of Parkinson’s disease(PD)is still poorly understood.Methods:High-resolution 3-tesla T1-weighted structural magnetic resonance images in sixty-five PD and 27 age-matched healthy control participants were examined.Putamen,caudate,and intracranial volumes were manually traced in the axial plane of 3D reconstructed images.Striatal nuclei volumes were normalized to intracranial volume for statistical comparison.Disease status was assessed using the Unified Parkinson’s Disease Rating Scale and Hoehn and Yahr scale.Cognitive status was assessed using global status tests and detailed neuropsychological testing.Results:Both caudate and putamen volumes were smaller in PD brains compared to controls after adjusting for age and gender.Caudate volumes were reduced by 11%(p=0.001)and putamen volumes by 8.1%(p=0.025).PD striatal volumes were not found to be significantly correlated with cognitive or motor decline.Conclusion:Small,but significant reductions in the volume of both the caudate and putamen occur in PD brains.These reductions are independent of the effects of age and gender,however the relation of these reductions to the functional loss of dopamine,which is characteristic of PD,remains unclear.	Toni L Pitcher Tracy R Melzer Michael R MacAskill Charlotte F Graham Leslie Livingston Ross J Keenan Richard Watts John C Dalrymple-Alford Tim J Anderson	2012	Translational Neurodegeneration2012，1，1：	2
2	Theoretical and experimental investigation of infrared properties of tapered silver/silver halide-coated hollow waveguides显示文摘	Bledt C M Melzer J E Harrington J A	2013	Appl Opt2013，52，16：	1
3	Synthesis of valsartan via decarboxylative biarylcoupling显示文摘	Goossen L J Melzer B	2007	Journal of Organic Chemistry2007，72，19：	1
4	Topographic ooze: Building the eastern margin of Tibet by lower crustal flow显示文摘	SCHLUNEGGER F MELZER J CLARK M K	2000	Geology2000，28，：	1
5	Flowering-time genes modulate meristem determinacy and growth form in Arabidopsis thaliana显示文摘	Melzer S Lens F Gennen J et aI	2008	Nature Genetics2008，40，：	1
6	Ethylcellulose:a new type of emul-sion stabilizer显示文摘	Melzer E Kreuter J Daniels R	2003	European Journal of Pharmaceutics and Biopharmaceutics2003，56，1：	1
7	Prevalence of chlamycliae in boars and semen used for artificial insemination显示文摘	Kauffold J Melzer F Henning K	2006	Theriogenology2006，65，9：	1
8	Correlation between reversed-phase retention and solute molecular surface type and area: Ⅱ Retention of low polarity nora hydrocarbonaceous surfaces 显示文摘	MOCKEL H J HOFLER F MELZER H	1987	Journal of Chromatography A1987，388，：	1
9	DNA-protein crosslinks,a biomarker of exposure to formaldehyde in vitro and in vivo studies显示文摘	Shaham J Bomstein Y Melzer A	1996	Carcinogenesis1996，17，1：	1
10	Ethylcellulose : a new type of emulsion stabilizer 显示文摘	Melzer E Kreuter J Daniels R	2003	European Journal of Pharma- ceutics and Biopharmaceuties2003，56，1：	1
11	Mineral matter transformation during Sasol-Lurgi fixed bed dry bottom gasification-utilization of HT-XRD and FactSage modelling显示文摘	van Dyk J C Melzer S Sobiecki A	2006	Minerals Engineering2006，19，10：	1
12	Association between ankle muscle strength and limit of stability in older adults显示文摘	MELZER I BENJUYA N KAPLANSKI J	2009	Age Ageing2009，38，：	1
13	Diversity and mealybug transmissibility of ampeloviruses in pineapple显示文摘	Sether D M Melzer M J Busto J	2005	Plant Disease2005，89，5：	1
14	Preliminary data of a HAMD - 17 validated symptom scale derived from the ICD - 10 to diagnose depres- sion in outpatients显示文摘	Melzer J Rostock M Brignoli R eta/	2012	Forsch Komplement treed2012，19，：	1
15	A proteome approach defines protective functions of tobacco leaf trichomes 显示文摘	Amine S Rutten T Melzer M Sonsmann G Vissers J P Schlesier B Mock H P	2005	Proteomics2005，5，10：	1
16	Diversity and mealybug transmissibility of ampeloviruses in pineapple显示文摘	Sether D M Melzer M J Busto J	2005	Plant Disease2005，89，5：	1
17	Nucleotide sequence, genome organization and phylogenetic analysis of pineapple mealybug wilt - associated virus - 2显示文摘	Melzer M J Karasev A V Sether D M	2001	Journal of General Virolog2001，82，：	1
18	Molecular characterization of a new plasmid-encoded SHV-type beta-lactamase (SHV-2 variant) conferring high level cefotaxime resistance upon Klebsiella pneumoniae显示文摘	PODBIELSKI A SCHONLING J MELZER B	1991	Mar1991，137，3：	1
19	FPF1 modulatesthe compentence to flowering in Arabidopsis显示文摘	Melzer S Kampmann G Chandler J	1999	Plant Journal1999，18，4：	1
20	Clinical studies on the efficacyand safety of padma 28,a complex herbal formulation from Tibet-an medicine: an overview显示文摘	Vennos C Melzer J Sailer R	2013	Forsch Komplementarmed2013，20，2：	1

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