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| 1 | Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis显示文摘Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course.Determination of inflammatory state is crucial for the assessment of disease activity and for tailoring therapy.However,no simple diagnostic test for monitoring intestinal inflammation is available.Noninvasive markers give only indirect assessments of disease activity.Histopathological or endoscopical examinations accurately assess inflammatory activity,but they are invasive,time consuming and expensive and therefore are unsuitable for routine use.Imaging procedures are not applicable for ulcerative colitis.The usefulness of ultrasound and Doppler imag-ing in assessing disease activity is still a matter of discussion for Crohn's disease,and an increased interest in computed tomography enterograph (CTE) has been seen,mainly because it can delineate the extent and severity of bowel wall inflammation,besides detecting extraluminal findings.Until now,the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE.Due to this,clinical activity indices are still commonly used for both diseases. | Eduardo Garcia Vilela Henrique Osvaldo da Gama Torres Fabiana Paiva Martins Maria de Lourdes de Abreu Ferrari Marcella Menezes Andrade Aloísio Sales da Cunha | 2012 | World Journal of Gastroenterology2012,18,9: | 23 |
| 2 | What exists beyond cag A and vacA? Helicobacter pylori genes in gastric diseases显示文摘Helicobacter pylori(H. pylori) infection is present in more than half the world's population and has been associated with several gastric disorders, such as gastritis, peptic ulceration, and gastric adenocarcinoma.The clinical outcome of this infection depends on host and bacterial factors where H. pylori virulence genes seem to play a relevant role. Studies of cag A and vac A genes established that they were determining factors in gastric pathogenesis. However, there are gastric cancer cases that are cag A-negative. Several other virulence genes have been searched for, but these genes remain less well known that cag A and vac A. Thus, this review aimed to establish which genes have been suggested as potentially relevant virulence factors for H. pylori-associated gastrointestinal diseases. We focused on the cag-pathogenicity island, genes with adherence and motility functions, and ice A based on the relevance shown in several studies in the literature. | Débora Menezes da Costa Eliane dos Santos Pereira Silvia Helena Barem Rabenhorst | 2015 | World Journal of Gastroenterology2015,21,37: | 6 |
| 3 | Conservative strategy for treatment of stable coronary artery disease显示文摘Patients with coronary artery disease vary widely in terms of prognosis, which is mainly dependent on ventricular function. In relation to the major outcomes of death and myocardial infarction, it is not clear in the literature if an invasive strategy of myocardial revascularization is superior to a conservative strategy of optimized medical therapy. Moreover, with the exception of patients with left main coronary disease, this similarity in prognosis also occurs in different subgroups of patients. | Paulo Cury Rezende Thiago Luis Scudeler Leandro Menezes Alves da Costa Whady Hueb | 2015 | World Journal of Clinical Cases2015,3,2: | 3 |
| 4 | Glial fibrillary acidic protein levels are associated with global histone H4 acetylation after spinal cord injury in rats显示文摘Emerging evidence has suggested global histone H4 acetylation status plays an important role in neural plasticity. For instance, the imbalance of this epigenetic marker has been hypothesized as a key factor for the development and progression of several neurological diseases. Likewise, astrocytic reactivity-a wellknown process that markedly influences the tissue remodeling after a central nervous system injury-is crucial for tissue remodeling after spinal cord injury(SCI). However, the linkage between the above-mentioned mechanisms after SCI remains poorly understood. We sought to investigate the relation between both glial fibrillary acidic protein(GFAP) and S100 calcium-binding protein B(S100B)(astrocytic reactivity classical markers) and global histone H4 acetylation levels. Sixty-one male Wistar rats(aged ~3 months) were divided into the following groups: sham; 6 hours post-SCI; 24 hours post-SCI; 48 hours post-SCI; 72 hours post-SCI; and 7 days post-SCI. The results suggested that GFAP, but not S100B was associated with global histone H4 acetylation levels. Moreover, global histone H4 acetylation levels exhibited a complex pattern after SCI, encompassing at least three clearly defined phases(first phase: no changes in the 6, 24 and 48 hours post-SCI groups; second phase: increased levels in the 72 hours post-SCI group; and a third phase: return to levels similar to control in the 7 days post-SCI group). Overall, these findings suggest global H4 acetylation levels exhibit distinct patterns of expression during the first week post-SCI, which may be associated with GFAP levels in the perilesional tissue. Current data encourage studies using H4 acetylation as a possible biomarker for tissue remodeling after spinal cord injury. | Mayara Ferraz de Menezes Fabricio Nicola Ivy Reichert Vital da Silva Adriana Vizuete Viviane Rostirola Eisner Leder Leal Xavier Carlos Alberto Saraiva Goncalves Carlos Alexandre Netto Regis Gemerasca Mestriner | 2018 | Neural Regeneration Research2018,13,11: | 2 |
| 5 | Specific consumption of liquid biofuels in gasoline fuelled engines显示文摘 | Renato Catalufia Rosngela da Silva Eliana Weber de Menezes | 2008 | Fuel2008,87,1516: | 1 |
| 6 | Diversity of rotavirus strains circulating in Northern Brazil after introduction of a rotavirus vaccine: High prevalence of G3P[6] genotype显示文摘 | Luana da Silva Soares Sylvia de Fátima dos Santos Guerra Alessilva do Socorro Lima de Oliveira Fabiola da Silva dos Santos Euzeni Maria de Fátima Costa de Menezes Joana d’Arc Pereira Mascarenhas Alexandre C. Linhares | 2014 | Virol2014,,6: | 1 |
| 7 | Flooding effects on phosphorus dynamics in an Amazonian mangrove forest, Northern Brazil 显示文摘 | MENDOZA U N DA CRUZ C C MENEZES MP | 2012 | Plant and Soil2012,353,: | 1 |
| 8 | Hydatid cyst of the liver - criteria for the selection of appropriate treatment 显示文摘 | Menezes da Silva A | 2003 | Acta Trop2003,85,2: | 1 |
| 9 | Successful use of rib grafts for cranio-plasty in children显示文摘 | Taggard DA Menezes AH | 2001 | Pediatr-Meurosurg2001,24,3: | 1 |
| 10 | Hyperglycemia induces memory impairment linked to increased acetylcholinesterase activity in zebrafish ( Danio rerio )显示文摘 | Katiucia Marques Capiotti Daiani Almeida De Moraes Fabiano Peres Menezes Luiza Wilges Kist Maurício Reis Bogo Rosane Souza Da Silva | 2014 | Behavioural Brain Research2014,,: | 1 |
| 11 | Hydatid cyst of the liver-criteria for the selection of appropriate treatment 显示文摘 | Menezes da Silva A | 2003 | Acta Trop2003,85,2: | 1 |
| 12 | Stimulation by foxod proteins plays a critical role in the maturation of the immune system显示文摘 | da SILVA MENEZES J de SOUSA MUCIDA D CARA D C | 2003 | International Immunology2003,15,3: | 1 |
| 13 | Effect of ethers and ether/ethanol additives on the physicochemical properties of diesel fuel and on engine tests 显示文摘 | de Menezes E W da Silva R Catalufia R | 2006 | Fuel2006,85,5: | 1 |
| 14 | Specific consumption of liquid l:iofuels in gasoline fuelled engines 显示文摘 | Renato Catalufia Rosangela da Silva Eliana Weber de Menezes | 2008 | Fuel2008,87,1516: | 1 |
| 15 | Role of pefiaqueduetal gray on the cardiovascular response evoked by disinhibition of the dorsomedial hypothalamus显示文摘 | da Silva LG de Menezes RC dos Santos RA | 2003 | Brain Res2003,984,12: | 1 |
| 16 | Excitatory amino acid receptors in the periaqueductal gray mediate the cardiovascular response evoked by activation of dorsomedial hypothalamic neurons显示文摘 | da Silva LG Jr Menezes RC Villela DC | 2006 | Neuroscienee2006,139,3: | 1 |
| 17 | A transgenetic algorithm applied to the Traveling Car Renter Problem显示文摘 | Marco C. Goldbarg Elizabeth F.G. Goldbarg Paulo H. Asconavieta Matheus da S. Menezes Henrique P.L. Luna | 2013 | Expert Systems With Applications2013,,16: | 1 |
| 18 | Successful use of rib grafts for craioplasty in children显示文摘 | Taggard DA Menezes AH | 2001 | Pediatr Neurosurg2001,34,8: | 1 |
| 19 | Diffusion tensor imaging of the median nerve before and after carpal tunnel release in patients with carpal tunnel syndrome: feasibility study显示文摘 | Naraghi A da Gama Lobo L Menezes R | 2013 | Skeletal Radiol2013,42,: | 1 |
| 20 | Successful use of rib grafts for cranioplasty in children 显示文摘 | Taggard DA Menezes AH | 2001 | Pediatr-Nurosurg2001,34,3: | 1 |