|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Vascular protection and regenerative effects of intranasal DL-3-N butylphthalide treatment after ischaemic stroke in mice显示文摘Objective To investigate the effects of DL-3-N butylphthalide(NBP)via intranasal delivery after ischaemic stroke in mice.Methods C57BL/6 mice were divided into three groups:sham,stroke with vehicle and stroke with NBP treatment.Ischaemic stroke was induced by permanent ligation of right middle cerebral artery with 7 min common carotid artery occlusion.NBP(100 mg/kg)or vehicle was intranasally administered at 1 hour after stroke and repeated once a day until sacrifice.Bromodeoxyuridine(BrdU)(50 mg/kg/day)was given from the third day until sacrifice.Sensorimotor function was tested during 1-21 days after stroke.Local cerebral blood flow in the ischaemic and peri-infarct regions was measured using laser Doppler flowmetry before,during and 3 days after ischaemia.Expressions of vascular endothelial growth factor(VEGF)and endothelial nitric oxide synthase as well as regenerative marker BrdU in the peri-infarct region were analysed by western blotting and immunohistochemical methods.Results Compared with the vehicle group,NBP treatment significantly increased the VEGF expression in the poststroke brain.Stroke mice that received NBP showed significantly less vascular damage after stroke and more new neurons and blood vessels in the peri-infarct region at 21 days after stroke.In the adhesive removal test,the sensorimotor function of stroke mice treated with NBP performed significantly better at 1,3 and 7 days after stroke compared with vehicle controls.Conclusion Daily intranasal NBP treatment provides protective and neurogenic/angiogenic effects in the poststroke brain,accompanied with functional improvements after a focal ischaemic stroke in mice. | Mengyao Qu Jingjie Zhao Yingying Zhao Jinmei Sun Liping Liu Ling Wei Yongbo Zhang | 2021 | Stroke & Vascular Neurology2021，6，1： | 4 |
| 2 | Propofol Protects Regulatory T Cells, Suppresses Neurotoxic Astrogliosis, and Potentiates Neurological Recovery After Ischemic Stroke显示文摘Dear Editor,Emergency intravascular thrombectomy is the best treatment for acute ischemic stroke [1]. However, it is controversial whether the use of general anesthesia during emergency intravascular thrombectomy affects patient recovery. | Yuzhu Wang Dan Tian Yushang Zhao Mengyao Qu Yuhualei Pan Changwei Wei Yanbing Zhu Anshi Wu | 2021 | Neuroscience Bulletin2021，37，5： | 3 |
| 3 | Prediction of Apple Fruit Quality by Soil Nutrient Content and Artificial Neural Network显示文摘The effect of soil nutrient content on fruit yield and fruit quality is very important.To explore the effect of soil nutrients on apple quality we investigated 200 fruit samples from 40 orchards in Feng County,Jiangsu Province.Soil mineral elements and fruit quality were measured.The effect of soil nutrient content on fruit quality was analyzed by artificial neural network(ANN)model.The results showed that the prediction accuracy was highest(R2=0.851,0.847,0.885,0.678 and 0.746)in mass per fruit(MPF),hardness(HB),soluble solids concentrations(SSC),titratable acid concentration(TA)and solid-acid ratio(SSC/TA),respectively.The sensitivity analysis of the prediction model showed that soil available P,K,Ca and Mg contents had the greatest impact on the quality of apple fruit.Response surface method(RSM)was performed to determine the optimum range of the available P,K,Ca,and Mg contents in orchards In Feng County,which were 10∼20 mg⋅kg^(−1),170∼200 mg⋅kg^(−1),1000∼1500 mg⋅kg^(−1),and 80∼200 mg⋅kg^(−1),respectively.The research also concluded that improving the content of available P and available Ca in orchard soil was crucial to improve apple fruit quality in Feng County,Jiangsu Province. | Mengyao Yan Xianqi Zeng Banghui Zhang Hui Zhang Di Tan Binghua Cai Shenchun Qu Sanhong Wang | 2023 | Phyton-International Journal of Experimental Botany2023，92，1： | 0 |
| 4 | A comparative study of long-time series of global-scale albedo products显示文摘Albedo is a key variable in the study of global or regional earth system models.High-quality albedo products are helpful for the accurate analysis and prediction of the Earth’s environment and climate.This paper analyzes the similarities and differences in several global-scale albedo products.The conclusions are as follows:(1)Ignoring the downward radiation weight leads to a maximum deviation of±0.2 in the mean albedo in space and time;(2)Most of the products have good consistency at the global scale,especially after 2000,the consistency in the middle latitudes is better than that in the low latitudes and high latitudes;(3)Although there are obvious inter-annual variations and zonal differences in global mean albedo data from 2000 to 2020,the overall trend is not significant.The complex spatio-temporal variation of albedo requires high-quality remote sensing products to characterize its details.However,existing datasets do not show good agreement in these details,and more efforts are needed in this area. | Li Mengyao Liu Qiang Qu Ying | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员