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| 1 | Distribution of ^3H—nicotine in Rat Tissues Under the Influence of Simulated Microgravity显示文摘Rat tail suspension offers a useful model to reproduce physiologic responses to weightlessness.The present study was conducted in the head-down-tilt(HDT) rat model to assess changes in metabolism of body tissues employing 3H-nicotine. Twelve male rats were used in the study. Half of the rats were tail suspended at 30°for two weeks on a 12/12 light/dark cycle. During this period,body weight, food and fluid intakes were measured. At term, animals were anesthetized and injected IV withe a solution contaming 4 microuries of micotine. After 90 min the animals were sacrificed, exsanguinated and tissues (brain,blood,trachea,salivary gland,lung,heart,esophagus,spleen, kidneys and testes) were harvested. The distribution of 3H-nicotine per gram of each tissue was determinded and ealeulated as percent of total injected radioactivity. Final body weights of suspended ammals were significantly (P < 0.0 5) lower than those of eontrols(309±21 vs 350±11g). 3HNicotine waw retained in greatest amounts by the kindneys, followed inorder by salivary glands, spleen, and gastrointestinal tissues. compared to non-suspended control, the tissue retention of nicotine in suspended animals was decreased in the following tissues:esphyagus (25 %), aorta (25%). fundus (25%), trachea (22%), adrenals (18%), spleen (17 %), and pancreas (12 %). The decreased retention of mcotine in tissues from suspended animals may be indicative of the fluid shifts and changes in blood flow to those tissue beds. The lack of differnces in nicotine retention in liver and kidney between control and suspended groups may implicate a normal metabolic function of these organs even under simulated weightlessness. | PARIMAL CHOWDHURY MICHAEL E. SOULSBY AND JAMES N. PASLEY (Department of Physiology and Biophysics, University of Arkansas for Medical Scienses, Little Rock, Arkansas 72205, USA) | 1999 | Biomedical and Environmental Sciences1999，12，2： | 6 |
| 2 | Investigation of impact of DC component on breakdown characteristics for different electric fields under composite AC&DC voltage显示文摘The valve side of the converter in the high‐voltage direct current is subjected to mixed voltages such as composite AC&DC voltage.In this study,the effects of the homo-geneity of electric field on breakdown voltage were investigated for different�DC component amplitudes of the composite voltage.The field efficiency factor was calcu-lated using mean and maximum field strengths for all of them.Variation of breakdown voltage of air was examined under the composite AC&DC voltage for different ratios�DC.As one result of the study,the breakdown occurs at the positive half‐wave of the AC voltage despite−DC voltage being applied due to positive corona discharge pulses.This breakdown point is named as the polarity change point.The breakdown voltage increases with the decrease of DC voltage component up to polarity change point in non‐uniform electric field.In less uniform electric field,the AC breakdown voltage was measured slightly higher than the DC breakdown voltage.In less uniform electric field,as the ratio of the applied AC voltage to DC voltage increases,the breakdown voltage gradually approaches the AC breakdown voltage.This result is similar to the result ob-tained for the+DC component in non‐uniform electric field experiments. | Mehmet Murat Ispirli Özcan Kalenderli Florian Seifert Michael Rock Bülent Oral | 2022 | High Voltage2022，7，2： | 2 |
| 3 | The Comparative Politics of Corruption: Accounting for the East Asian Paradox in Empirical Studies of Corruption, Growth and Investment显示文摘 | Michael T. Rock | 2004 | World Development2004，，6： | 1 |
| 4 | Prevention of cervix cancer 显示文摘 | Rock CL Michael CW Reynolds RK | 2000 | Crit Rev Oncol Hematol2000，33，： | 1 |
| 5 | Prevention of cervix cancer显示文摘 | Rock CL Michael CW Reynolds RK | 2000 | Crit Rev Oncol Hematol2000，33，3： | 1 |
| 6 | Prevention of cervix carcinoma显示文摘 | Rock CL Michael CW Reynolds RK | 2000 | Crit Rev Oncol Henmtol2000，33，3： | 1 |
| 7 | And Heidi Bonnett, The Comparative Politics of Corruption: Accounting for the East Asian Paradox in Empirical Studies of Corruption, Growth and Investment显示文摘 | Rock Michael T | 2004 | World Development2004，32，6： | 1 |
| 8 | Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a south African population of diverse HLA types are conserved in circulating field strains 显示文摘 | Marietjie Venter Michael Rock Adrian J Puren | 2003 | Journal of Virology2003，77，13： | 1 |
| 9 | Prevention ofcervix cancer显示文摘 | ROCK C L MICHAEL C W REYNOLDS R K | 2000 | Crit Rev Oncol Hematol2000，33，3： | 1 |
| 10 | A Comparison of Psoas Compartment Block and Spinal and General Anesthesia for Outpatient Knee Arthroscopy显示文摘 | Christopher J. Jankowski James R. Hebl Michael J. Stuart Michael G. Rock Mark W. Pagnano Christopher M. Beighley Darrell R. Schroeder Terese T. Horlocker | 2003 | Anesthesia & Analgesia2003，，4： | 1 |
| 11 | The Comparative Politics of Corruption: Accounting for the East Asian Paradox in Empirical Studies of Corruption, Growth and Investment显示文摘 | Michael T. Rock | 2004 | World Development2004，，6： | 1 |
| 12 | Freshwater use,freshwater scarcity,and socioeconomic development显示文摘 | ROCK MICHAEL T | 1998 | The Journal of Environment&Development1998，7，3： | 1 |
| 13 | Prevention ofcervix cancer显示文摘 | Rock C L Michael C W Reynolds R K | 2000 | Crit Rev Oncol Hematol2000，33，3： | 1 |
| 14 | Prevention of cervix carcinoma 显示文摘 | Rock CL Michael CW Reynolds RK | 2000 | Crit Rev Oncol Hematol2000，33，3： | 1 |
| 15 | Prevention of cervix cancer显示文摘 | Rock CL Michael CW Reynolds RK | | 0，，03： | 1 |
| 16 | Correction of HDL Dysfunction in Individuals With Diabetes and the Haptoglobin 2-2 Genotype显示文摘 | Asleh Rabea Blum Shany Kalet-Litman Shiri Alshiek Jonia Miller-Lotan Rachel Asaf Roy Rock Wasseem Aviram Michael Milman Uzi Shapira Chen Abassi Zaid Levy Andrew P | 2008 | Diabetes2008，，10： | 1 |
| 17 | Prevention of cervix cancer 显示文摘 | Rock CL Michael CW Reynolds RK | 2000 | Crit Rev Oncol Hematol2000，33，3： | 1 |
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