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| 1 | Dual color optogenetic control of neural populations using low-noise,multishank optoelectrodes显示文摘Optogenetics allows for optical manipulation of neuronal activity and has been increasingly combined with intracellular and extracellular electrophysiological recordings.Genetically-identified classes of neurons are optically manipulated,though the versatility of optogenetics would be increased if independent control of distinct neural populations could be achieved on a sufficient spatial and temporal resolution.We report a scalable multisite optoelectrode design that allows simultaneous optogenetic control of two spatially intermingled neuronal populations in vivo.We describe the design,fabrication,and assembly of low-noise,multisite/multicolor optoelectrodes.Each shank of the four-shank assembly is monolithically integrated with 8 recording sites and a dualcolor waveguide mixer with a 7×30μm cross-section,coupled to 405 nm and 635 nm injection laser diodes(ILDs)via gradient-index(GRIN)lenses to meet optical and thermal design requirements.To better understand noise on the recording channels generated during diode-based activation,we developed a lumped-circuit modeling approach for EMI coupling mechanisms and used it to limit artifacts to amplitudes under 100μV upto an optical output power of 450μW.We implanted the packaged devices into the CA1 pyramidal layer of awake mice,expressing Channelrhodopsin-2 in pyramidal cells and ChrimsonR in paravalbumin-expressing interneurons,and achieved optical excitation of each cell type using sub-mW illumination.We highlight the potential use of this technology for functional dissection of neural circuits. | Komal Kampasi Daniel F.English John Seymour Eran Stark Sam McKenzie Mihály Vöröslakos György Buzsáki Kensall D.Wise Euisik Yoon | 2018 | Microsystems & Nanoengineering2018，4，1： | 8 |
| 2 | Soot combustion and NOx adsorption on Co, Ba, K/ZrO2 显示文摘 | Mih V G Banu's E D Ulla M A | 2008 | Catalysis Today2008，，： | 1 |
| 3 | Thermal analysis of K (x)/La2O3, active catalysts for the abatement of diesel exhaust contaminants 显示文摘 | Mih V G Querini C A Miro E E | 2003 | Thermochimica Acta2003，404，12： | 1 |
| 4 | Simultaneous removal of soot and nitrogen oxides from diesel engine exhausts显示文摘 | Pisarello M L Mih V Peralta M A | 2002 | Catalysis Today2002，75，14： | 1 |
| 5 | Abatement of diesel-exhaust pollutants: NOx storage and soot combustion on K/La2O3 catalysts 显示文摘 | Mih V G Pissarello M L Miro E E | 2003 | Applied Catalysis B: Environmental2003，41，4： | 1 |
| 6 | NOx trapping and soot combustion on BaCoO3-y pemvskite:LRS and FFIR characterization显示文摘 | Mih V G Ulla M A Mira E E | 2005 | Applied Catalysis B : Environmental2005，57，1： | 1 |
| 7 | Soot combustion and NOx adsorption on Co, Ba, K/ZrO2 显示文摘 | Mih V G Banus E D Ulla M A | 2008 | Catalysis Today2008，，： | 1 |
| 8 | Soot oxidation on a catalytic NOx trap: Beneficial effect of the Ba-K interaction on the sulfated Ba, K/CeO2 catalyst显示文摘 | Mih V G Peralta M A Ulla M A | 2007 | Catalyst Communications2007，8，5： | 1 |
| 9 | Components of Self-regulated Learning; Implications for School Performance 显示文摘 | Mih C Mih V | 2010 | Acta Didactiea Napocensia2010，3，1： | 1 |
| 10 | Abatement of Diesel-Exhaust Pollutants:NO Storage and Soot Combustion on K/La2O3 Catalysts显示文摘 | Pissarello M L Miro E E | 2003 | Applied Catalysis B:Environmental2003，，41： | 1 |
| 11 | A simpler model for concentrated vortices显示文摘 | Vatistas G H Kozel V Mih W C | 1991 | Experiments in Fluids1991，11，1： | 1 |
| 12 | Air Pollution Assessment Based on Elemental Concentration of Leaves Tissue and Foliage Dust Along an Urbanization Gradient in Vienna显示文摘 | Edina S Mihály B Andreas V | | 0，，5： | 1 |
| 13 | Transalkylation of toluene with cumene over zeolites Y clealuminated in solid-state显示文摘 | MAVRODINOVA V POPOVA M MIH LYI R | 2003 | Applied Catalysis A: General2003，248，： | 1 |
| 14 | Soot oxidation on a catalytic NOx trap:beneficial effect of the Ba-K interaction on the suffated Ba,K/CeO2 catalyst显示文摘 | Mih V G Peralta M A Ulla M A | 2007 | Catalysis Communications2007，8，5： | 1 |
| 15 | Measurement of IL-13-induced i NOS-derived gas phase nitric oxide in human bronchial epithelial cells显示文摘 | Suresh V Mih JD George SC | 2007 | Am J Respir Cell Mol Biol2007，37，1： | 1 |
| 16 | A simpler model for concentrated vortices显示文摘 | Vatistas G H Kozel V Mih W C | 1991 | Experiments in Fluids1991，11，1： | 1 |
| 17 | A Multiplicity Result for a Nonlinear Degenerate Problem Arising in the Theory of Electrorheological Fluids显示文摘 | MIHˇAILESCU M RDULESCU V | 2006 | Proc R Soc Lond Ser A2006，462，： | 1 |
| 18 | Polyacrylonitrile single-walled carbon nanotube composite fibers显示文摘 | Sreekumar T V Liu T Mih B G | 2004 | Advanced Materials2004，16，： | 1 |
| 19 | A simpler model for concentrated vortices显示文摘 | VATISTAS G H KOZEL V MIH W C | 1991 | Experiments in Fluids1991，11，： | 1 |
| 20 | A simpler model for concentrated vortices 显示文摘 | VATISTAS G H KOZEL V MIH W C | 1991 | Experiments in Fluids1991，11，： | 1 |
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