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| 1 | Portal hypertensive gastropathy:A systematic review of thepathophysiology,clinical presentation,natural history andtherapy显示文摘AIM: To describe the pathophysiology, clinical presentation, natural history, and therapy of portal hypertensive gastropathy(PHG) based on a systematic literature review.METHODS: Computerized search of the literature was performed via Pub Med using the following medical subject headings or keywords: 'portal' and 'gastropathy'; or 'portal' and 'hypertensive'; or 'congestive' and 'gastropathy'; or 'congestive' and 'gastroenteropathy'. The following criteria were applied for study inclusion: Publication in peer-reviewed journals, and publication since 1980. Articles were independently evaluated by each author and selected for inclusion by consensus after discussion based on the following criteria: Well-designed, prospective trials; recent studies; large study populations; and study emphasis on PHG. RESULTS: PHG is diagnosed by characteristic endoscopic findings of small polygonal areas of variable erythema surrounded by a pale, reticular border in a mosaic pattern in the gastric fundus/body in a patient with cirrhotic or non-cirrhotic portal hypertension. Histologic findings include capillary and venule dilatation, congestion, and tortuosity, without vascular fibrin thrombi or inflammatory cells in gastric submucosa. PHG is differentiated from gastric antral vascular ectasia by a different endoscopic appearance. The etiology of PHG is inadequately understood. Portal hypertension is necessary but insufficient to develop PHG because many patients have portal hypertension without PHG.PHG increases in frequency with more severe portal hypertension, advanced liver disease, longer liver disease duration, presence of esophageal varices, and endoscopic variceal obliteration. PHG pathogenesis is related to a hyperdynamic circulation, induced by portal hypertension, characterized by increased intrahepatic resistance to flow, increased splanchnic flow, increased total gastric flow, and most likely decreased gastric mucosal flow. Gastric mucosa in PHG shows increased susceptibility to gastrotoxic chemicals and poor wound healing. Nitrous oxide, free radicals, tumor necrosis factor-alpha, and glucagon may contribute to PHG development. Acute and chronic gastrointestinal bleeding are the only clinical complications. Bleeding is typically mild-to-moderate. Endoscopic therapy is rarely useful because the bleeding is typically diffuse. Acute bleeding is primarily treated with octreotide, often with concomitant proton pump inhibitor therapy, or secondarily treated with vasopressin or terlipressin. Nonselective β-adrenergic receptor antagonists, particularly propranolol, are used to prevent bleeding after an acute episode or for chronic bleeding. Iron deficiency anemia from chronic bleeding may require iron replacement therapy. Transjugular-intrahepaticportosystemic-shunt or liver transplantation is highly successful ultimate therapies because they reduce the underlying portal hypertension.CONCLUSION: PHG is important to recognize in patients with cirrhotic or non-cirrhotic portal hypertension because it can cause acute or chronic GI bleeding that often requires pharmacologic therapy. | Mihajlo Gjeorgjievski Mitchell S Cappell | 2016 | World Journal of Hepatology2016，8，4： | 38 |
| 2 | Cystic lymphangioma of the pancreas显示文摘Lymphangioma of the pancreas is an extremely rare benign tumour of lymphatic origin,with fewer than 60 published cases. Histologically,it is polycystic,with the cysts separated by thin septa and lined with endothelial cells. Though congenital,it can affect all age groups,and occurs more frequently in females. Patients usually present with epigastric pain and an associated palpable mass. Complete excision is curative,even though,depending on the tumour location,surgery may be simple or involve extensive pancreatic resection and anastomoses. The authors present a 49-year-old woman in whom a polycystic septated mass,35 mm x 35 mm in size,was discovered by ultrasonography (US) in the body of the pancreas during investigations for epigastric pain and nausea. At surgery,a well circumscribed polycystic tumor was completely excised,with preservation of the pancreatic duct. The postoperative recovery was uneventful. Histology confirmed a microcystic lymphangioma of the pancreas. Immunohistochemistry showed cystic endothelial cells reactivity to factor Ⅷ -RA (++),CD31 (+++) and CD34 (-). Postoperatively,abdominal pain disappeared and the patient remained symptomfree for 12 mo until now. Although extremely rare,lymphangioma of the pancreas should be taken into consideration as a differential diagnosis of a pancreatic cystic lesion,especially in women. | Radoje B Colovic Nikica M Grubor Marjan T Micev Henry Dushan E Atkinson Vitomir I Rankovic Mihajlo M Jagodic | 2008 | World Journal of Gastroenterology2008，14，44： | 6 |
| 3 | A further study of the kinetics and optimization of the essential oil hydrodistillation from lavender flowers显示文摘Hydrodistillation has commonly been used to recover essential oil from various plant materials,including lavender(Lavandula officinalis) flowers.The main objectives of the present study were to model the kinetics of the lavender essential oil(LEO) hydrodistillation using a phenomenological model,to evaluate the statistical significance of the hydromodule and hydrodistillation time on LEO yield combining a 4~2 full factorial design with the response surface methodology,to model statistically LEO yield by multiple non-linear regression and to determine the optimal process conditions that provided the maximum LEO yield.The fast-essential oil distillation(washing stage) in the initial period and the slow diffusion stage until the saturation occurring simultaneously were observed,justifying the use of the phenomenological model.With increasing the hydromodule,the saturation LEO yield and the washable fraction of the LEO decreased while the washing and diffusion rate constants increased.Knowledge of the LEO oil yield and the hydrodistillation kinetics is important from the techno-economical point of view. | Aleksandra Perovic Mihajlo Z.Stankovic Vlada B.Veljkovic Milan D.Kostic Olivera S.Stamenkovic | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 3 |
| 4 | Cross-Sectional Survey on Complementary and Alternative Medicine Awareness among Health Care Professionals and Students Using CHBQ Questionnaire in a Balkan Country显示文摘在互补、其他的药(凸轮) 的态度,知识,和使用上进行研究的目的在塞尔维亚的治疗。关于在这个区域的凸轮治疗的可得到的数据是少见的,意见从健康缺乏扇区。巴尔干的区域国家在在凸轮治疗上发出国家政策有延期。使用的问询表基于的方法以前验证了凸轮健康信仰问询表(CHBQ ) ,作为 5 条款 Likert 类型规模提出了,为本地环境调整了。护理学生和专业人员被评估。问询表在凸轮治疗的态度,知识和使用上理解 10 个关上的问题。这调查在塞尔维亚的八个城市里被进行, 1 月 2010July 日 2011。797 个参加者的一个总数被包括。秒组参加者是 145 个保健专业人员(50 学术职员, 64 临床的职员, 19 个药剂师, 6 位另外的临床的分支专家和 6 个护士) 。数据被会见收集。应试者能获得 70 个点的最大值, 35 代表中立态度。牙科的结果学生(54.65 换 ???? , | Mihajlo B Jakovljevic Vera Djordjevic Veroljub Markovic Olivera Milovanovic Nemanja K Rancic Snezana M Cupara | 2013 | Chinese Journal of Integrative Medicine2013，19，9： | 2 |
| 5 | Effects of sulphate-sulphide mineral water ' mlje anica' in patients with hypertension 显示文摘 | Tatjana ER Mihajlo S | 2014 | Mater Sociomed2014，26，6： | 1 |
| 6 | Optimum design criteria for an Organic Rankine cycle using low-temperature geothermal heat sources显示文摘 | H.D. Madhawa Hettiarachchi Mihajlo Golubovic William M. Worek Yasuyuki Ikegami | 2007 | Energy2007，，9： | 1 |
| 7 | 查看详情显示文摘 | Vladimir M Stojanovic Mihajlo Vanevic | | 0，，： | 1 |
| 8 | Health risks of heavy metals in the mediterranean mussels as seafood显示文摘 | Slavka Stankovic Mihajlo Jovic | 2012 | Environmental Chemistry Letters2012，，2： | 1 |
| 9 | A theoretical investigation of the geometries and binding energies of molecular tweezer and clip Host-Guest systems 显示文摘 | Maja P Mihajlo E Miljenko P etal | 2005 | J Chem Theory Comput2005，1，： | 1 |
| 10 | Optimum design criteria for an Organic Rankine cycle using low-temperature geothermal heat sources显示文摘 | H.D. Madhawa Hettiarachchi Mihajlo Golubovic William M. Worek Yasuyuki Ikegami | 2007 | Energy2007，，9： | 1 |
| 11 | The effect of longitudinal heat conduction in cross flow Indirect evaporative air coolers 显示文摘 | H D MADHAWA HETTIARACHI MIHAJLO GOLUBOVIC W M WOREK | 2007 | Applied Thermal Engineer2007，，27： | 1 |
| 12 | Is ultrasound useful in detection and follow-up of gastric foreign bodies in children?显示文摘 | Mihajlo Jeckovi? Sudha A. Anupindi Svetlana Balj Barbir Jovan Lovrenski | 2013 | Clinical Imaging2013，，： | 1 |
| 13 | Optimum design criteria for an organic Rankine cycle using low-temperature geothermal heat sources 显示文摘 | MADHAWA HETTIARACHCHI H D MIHAJLO G WILLIAM M W Y ASUYUKI I | 2007 | Energy2007，32，9： | 1 |
| 14 | The impact of health expenditures on public health in BRICS nations显示文摘1.Peculiarity of the BRICS emerging economies Since the late 1980s,accelerated globalization has provided economic growth opportunities in mature and emerging economies.The rapidly developing nations of Brazil,Russia,India,China,and South Africa(BRICS nations)have a combined economic output that makes BRICS countries the world's major emerging economies. | Mihajlo Jakovljevic Yuriy Timofeyev Natalia V.Ekkert Julia V.Fedorova Galina Skvirskaya Sergey Bolevich Vladimir A.Reshetnikov | 2019 | Journal of Sport and Health Science2019，8，6： | 1 |
| 15 | Heterotopic triplet pregnancy with laparoscopic resection of the rupture tube at ten weeeks of gestation显示文摘 | MIHAJLO STRELEC ROMANA DMITROVIC VELIMIR SIMUNIC | 2004 | Eur J of Obstet & Gynecol and Reprod Biol2004，117，1： | 1 |
| 16 | Optimum design criteria for an organic Rankine cycle using low-temperature geothermal heat sources显示文摘 | HETTIARACHCHI H D Madhawa GOLUBOVIC Mihajlo WOREK William M | 2007 | Energy2007，32，9： | 1 |
| 17 | The performance of the kalina cycle system ll(KCS-11) with low-temperature heat sources显示文摘 | Madhawa Hettiarachchi H D Mihajlo Golubovic William M Worek | 2007 | Journal of Energy Resources Technology2007，129，3： | 1 |
| 18 | Stimulative influ-ence of germination and growth of maize seedlings originatingfrom aged seeds by 2,4-D potencies显示文摘 | VESNA D MIHAJLO S MILENA S | 2013 | Homeopathy2013，102，3： | 1 |
| 19 | Optimum design criteria for an organic Ran- kine cycle using low geothermal heat resource显示文摘 | MADGAWA H H D MIHAJLO G WILLIAM M W | 2007 | En- ergy2007，32，9： | 1 |
| 20 | Development and validation of a new RP-HPLC method for determination of quercetin in green tea显示文摘 | Ivan M. Savic Vesna D. Nikolic Ivana M. Savic Ljubisa B. Nikolic Mihajlo Z. Stankovic | 2013 | Journal of Analytical Chemistry2013，，10： | 1 |
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