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2篇 您的检索式:作者名="Mike Salmon"
    题名 作者 年代 出处 被引量
1Immune regulation by CD4^+CD25^+ regulatory T cells:implications for transplantation tolerance 显示文摘Leonie Taamas Milica Vukmanovic - Stejic Mike Salmon 2003Transplant Immunology2003,11,:1
2Generation and characterization of novel stromal specific antibodies显示文摘Rheumatoid synovial fibroblasts were used as an immunogen to produce monoclonal antibodies selected for their reactivity with stromal cell antigens. Mice were immunised with low passage whole cell preparations and the subsequent hybridomas were screened by immunohistochemistry on rheumatoid synovium and tonsil sections. The aim was to identify those antibodies that recognised antigens that were restricted to stromal cells and were not expressed on CD45 positive leucocytes. A significant number of antibodies detected antigen that identified endothelial cells. These antibodies were further characterised to determine whether the vessels identified by these antibodies were vascular or lymphatic. From five fusions clones were identified with predominant reactivity with: 1) fibroblasts and endothelial cells; or 2) broad stromal elements (fibroblast, endothelium, epithelium, follicular dendritic cells). A fibroblast-specific antibody that did not also identify vessels was not generated. Examples of each reactivity pattern are discussed.Sapna HALDER Debbie L. HARDIE Dagmar SCHEEL-TOELLNER Mike SALMON Christopher D. BUCKLEY 2005Cell Research2005,15,9:0
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