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| 1 | 欧洲肿瘤内科协会对非上皮性卵巢癌的诊断、治疗和随访所制定的临床实践指南显示文摘非上皮性卵巢癌是一类少见的卵巢癌,因此,其诊断较难建立。然而,通过仔细观察各种肿瘤的标记物[尤其是人绒毛膜促性腺激素β亚单位(β-hCG)、α-甲胎蛋白(α-AFP)和乳酸脱氢酶(LDH)]、临床体征(如妊娠期体征, | Reed N Millan D Verheijen R Castiglione M On behalf of the ESMO Guidelines Working Group 杨华(译) 郎景和(审校) | 2011 | 国际妇产科学杂志2011，38，4： | 13 |
| 2 | Costimulation of resting B lymphocytes alters the IL-4-activated IRS2 signaling pathway in a STAT6 independent manner: implications for cell survival and proliferation显示文摘IL-4 is an important B cell survival and growth factor. IL-4 induced the tyrosine phosphorylation of IRS2 in resting B lymphocytes and in LPS- or CD40L-activated blasts. Phosphorylated IRS2 coprecipitated with the p85 subunit of PI 3’ kinase in both resting and activated cells. By contrast, association of phosphorylated IRS2 with GRB2 was not detected in resting B cells after IL-4 treatment although both proteins were expressed. However, IL-4 induced association of IRS2 with GRB2 in B cell blasts. The pattern of IL-4- induced recruitment of p85 and GRB2 to IRS2 observed in B cells derived from STAT6 null mice was identical to that observed for normal mice. While IL-4 alone does not induce activation of MEK, a MEKI inhibitor suppressed the IL-4-induced proliferative response of LPS-activated B cell blasts. These results demonstrate that costimulation of splenic B cells alters IL-4-induced signal transduction independent of STAT6 leading to proliferation. Furthermore, proliferation induced by IL-4 in LPS-activated blasts is dependent upon the MAP kinase pathway. | ZAMORANO JOSE,Unidad de Investigacion, Hospital San Pedro de Alcantara, Avda Millan Astray, 10003 Caceres ANN E KELLY, JONATHAN AUSTRIAN, HELEN Y WANG, ACHSAH D KEEGAN (Department of Immunology, Jerome Holland Labs, American Red Cross, Rockville, MD, USA | 2001 | Cell Research2001，11，1： | 4 |
| 3 | Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells显示文摘 | Studer D Millan C Ozturk E | 2012 | Eur C ell Mater2012，，24： | 1 |
| 4 | The appearance and modulation of osteocyte marker expression during calcification of vascular smooth muscle cells显示文摘 | Zhu D Mackenzie NC Millan JL | 2011 | PLoS One2011，6，19： | 1 |
| 5 | Merging photoredox catalysis with organocatalysis:the direct asymmetric alkylation of aldehydes显示文摘 | Nicewicz D A Mac Millan D W C | 2008 | Science2008，322，： | 1 |
| 6 | Xerostomia and quality of life after intensity modulated radiotherapy vs conventional radiotherapy for early stage nasopharyngeal initial report on a randomized control clinical trial显示文摘 | Pow E H Kwong D L Mc Millan A S | 2006 | Int J Radiat Oncol Biol Phys2006，66，98： | 1 |
| 7 | Content Annotation for the Se-mantic web:an Automatic Web - based Approach显示文摘 | Sanchez D Isern D Millan M | | 0，，03： | 1 |
| 8 | Local injection versussurgery in carpal tunnel syndrome: neurophysiologic outcomesof a randomized clinical trial 显示文摘 | Andreu JL Ly-Pen D Millan I | 2014 | Clin Neurophysiol2014，125，7： | 1 |
| 9 | Continuous- action Q-learning 显示文摘 | MILLAN J D R POSENATO D DEDIEU E | 2002 | Machine Learning2002，49，23： | 1 |
| 10 | Enantioselectiveα-trifluoromethylation of aldehydes via photoredox organocatalysis显示文摘 | Nagib D A Scott M E Mac Millan D W C | 2009 | J Am Chem Soc2009，131，10： | 1 |
| 11 | Ordered nanoparticle arrays formed on engineered chaperonin protein templates显示文摘 | Mc Millan R A Paavola C D Howard J | 2002 | Nature materials2002，1，4： | 1 |
| 12 | Cerebral developmental venous anomalies 显示文摘 | San Millan Ruiz D Gailloud P | 2010 | Childs Nerv Syst2010，26，10： | 1 |
| 13 | Thrombin activates nuclear factor - kappaB and potentiates endothelial cell activation by TNF显示文摘 | Anrather D Millan MT Palmetshofer A | 1997 | J Immunol1997，159，11： | 1 |
| 14 | Discovery of an{alpha}-amino C-H arylation reaction using the strategy of accelerated serendipity显示文摘 | Mc Nally A Prier C K Mac Millan D W C | 2011 | Science2011，334，： | 1 |
| 15 | Biomarkers of immunoregulatory status in stable liver transplantrecipients undergoing weaning of immunosup- pressive therapy 显示文摘 | Millan O Benitez C Guillen D | 2010 | Clinical Immunology2010，137，3： | 1 |
| 16 | A comparison of the validity of generic - and disease - specific measures in the assessment of oral health - related quality of life显示文摘 | Allen PF Mc - Millan AS Walshaw D | 1999 | Community Dent Oral Epidemiol1999，27，5： | 1 |
| 17 | Pathology findings with acrylic implants显示文摘 | San Millan Ruiz D Burkhardt K Jean B | 1999 | Bone1999，25，2： | 1 |
| 18 | Pathology findings with acrylic implants显示文摘 | San Millan Ruiz D Burkhardt K Jean B | 1999 | Bone1999，25，2： | 1 |
| 19 | Unsupervised adaptation for acceleration-based activity recognition: robustness to sensor displacement and rotation 显示文摘 | CHAVARRIAGA R BAYATI H MILLAN J D | 2013 | Personal and Ubiquitous Computing2013，17，3： | 1 |
| 20 | Efcient learning of variable-resolution cognitive maps for autonomous in door navigation显示文摘 | Arleo A Millan J D R Floreano D | | 0，，06： | 1 |
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