|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Probiotic supplementation decreases intestinal transit time: Meta-analysis of randomized controlled trials显示文摘AIM: To determine the efficacy of probiotic supplementation on intestinal transit time (ITT) and to identify factors that influence these outcomes. METHODS: A systematic review of randomized controlled trials (RCTs) of probiotic supplementation that measured ITT in adults was conducted by searching MEDLINE and EMBASE using relevant combinations. Main search limits included RCTs of probiotic supplementation in healthy or constipated adults that measured ITT. Study quality was assessed using the Jadad scale. A random effects meta-analysis was performed with standardized mean difference (SMD) of ITT between probiotic and control groups as the primary outcome. Meta-regression and subgroup analyses were conducted to examine the impact of moderator variables on ITT SMD. RESULTS: A total of 11 clinical trials with 13 treatment effects representing 464 subjects were included in this analysis. Probiotic supplementation was associated with decreased ITT in relation to controls, with an SMD of 0.40 (95%CI: 0.20-0.59, P < 0.001). Constipation (r 2 = 39%, P = 0.01), higher mean age (r 2 = 27%, P = 0.03), and higher percentage of female subjects (r 2 = 23%, P < 0.05) were predictive of decreased ITT with probiotics in meta-regression. Subgroup analyses demonstrated statistically greater reductions in ITT with probiotics in subjects with vs without constipation and in older vs younger subjects [both SMD: 0.59 (95%CI: 0.39-0.79) vs 0.17 (95%CI: -0.08-0.42), P = 0.01]. Medium to large treatment effects were identified with Bifidobacterium Lactis (B. lactis ) HN019 (SMD: 0.72, 95%CI: 0.27-1.18, P < 0.01) and B. lactis DN-173 010 (SMD: 0.54, 95%CI: 0.15-0.94, P < 0.01) while other single strains and combination products yielded small treatment effects. CONCLUSION: Overall, short-term probiotic supplementation decreases ITT with consistently greater treatment effects identified in constipated or older adults and with certain probiotic strains. | Larry E Miller Arthur C Ouwehand | 2013 | World Journal of Gastroenterology2013，19，29： | 9 |
| 2 | Dynamic failure in coal seams Implications of coal composition for bump susceptibility显示文摘As a contributing factor in the dynamic failure(bumping) of coal pillars,a bump-prone coal seam has been described as one that is ‘‘uncleated or poorly cleated,strong...that sustains high stresses.'Despite extensive research regarding engineering controls to help reduce the risk for coal bumps,there is a paucity of research related to the properties of coal itself and how those properties might contribute to the mechanics of failures. Geographic distribution of reportable dynamic failure events reveals a highly localized clustering of incidents despite widespread mining activities. This suggests that unique,contributing geologic characteristics exist within these regions that are less prevalent elsewhere. To investigate a new approach for identifying coal characteristics that might lead to bumping,a principal component analysis(PCA) was performed on 306 coal records from the Pennsylvania State Coal Sample database to determine which characteristics were most closely linked with a positive history of reportable bumping. Selected material properties from the data records for coal samples were chosen as variables for the PCA and included petrographic,elemental,and molecular properties. Results of the PCA suggest a clear correlation between low organic sulfur content and the occurrence of dynamic failure,and a secondary correlation between volatile matter and dynamic failure phenomena. The ratio of volatile matter to sulfur in the samples shows strong correlation with bump-prone regions,with a minimum threshold value of approximately 20,while correlations determined for other petrographic and elemental variables were more ambiguous. Results suggest that the composition of the coal itself is directly linked to how likely a coal is to have experienced a reportable dynamic failure event. These compositional controls are distinct from other previously established engineering and geologic criteria and represent a missing piece to the bump prediction puzzle. | Lawson Heather Weakley Andrew Miller Arthur | 2016 | International Journal of Mining Science and Technology2016，26，1： | 6 |
| 3 | The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting显示文摘 | Miriam Merad Priyanka Sathe Julie Helft Jennifer Miller Arthur Mortha | 2013 | Annual Review of Immunology2013，，： | 3 |
| 4 | Contemporary meta-analysis of short-term probiotic consumption on gastrointestinal transit显示文摘AIM: To determine the efficacy of probiotic supplementation on intestinal transit time(ITT) in adults and to identify factors that influence these outcomes. METHODS: We conducted a systematic review of randomized controlled trials of probiotic supplementation that measured ITT in adults. Study quality was assessed using the Jadad scale. A random effects meta-analysis was performed with standardized mean difference(SMD) of ITT between probiotic and control groups as the primary outcome. Meta-regression and subgroup analyses examined the impact of moderator variables on SMD of ITT.RESULTS: A total of 15 clinical trials with 17 treatment effects representing 675 subjects were included in this analysis. Probiotic supplementation was moderately efficacious in decreasing ITT compared to control, with an SMD of 0.38(95%CI: 0.23-0.53, P < 0.001). Subgroup analyses demonstrated statistically greater reductions in ITT with probiotics in subjects with vs without constipation(SMD: 0.57 vs 0.22, P < 0.01) and in studies with high vs low study quality(SMD: 0.45 vs 0.00, P = 0.01). Constipation(R^2 = 38%, P < 0.01), higher study quality(R^2 = 31%, P = 0.01), older age(R^2 = 27%, P = 0.02), higher percentage of female subjects(R^2 = 26%, P = 0.02), and fewer probiotic strains(R^2 = 20%, P < 0.05) were predictive of decreased ITT with probiotics in meta-regression. Medium to large treatment effects were identified with B. lactis HN019(SMD: 0.67, P < 0.001) and B. lactis DN-173 010(SMD: 0.54, P < 0.01) while other probiotic strains yielded negligible reductions in ITT relative to control.CONCLUSION: Probiotic supplementation is moderately efficacious for reducing ITT in adults. Probiotics were most efficacious in constipated subjects, when evaluated in high-quality studies, and with certain probiotic strains. | Larry E Miller Angela K Zimmermann Arthur C Ouwehand | 2016 | World Journal of Gastroenterology2016，22，21： | 2 |
| 5 | Political Issues and Trust in Government:1964-1970显示文摘 | Miller Arthur H | | 0，，： | 1 |
| 6 | Selenite protects human endothelial cells from oxidative damage and induces thioredoxin reductase显示文摘 | Miller S Walker S W Arthur J R | 2001 | Clin Sei2001，100，： | 1 |
| 7 | Selenoprotein expression in endothelial cells from different human vasculature and spcies显示文摘 | Miller S Walker SW Arthur JR | 2002 | Biochim Biophys Acta2002，1588，： | 1 |
| 8 | Selenite protects human endothelial cells from oxidative damage and induces thioredoxin reductase 显示文摘 | Miller S Walker SW Arthur JR | 2001 | Clinical science2001，100，5： | 1 |
| 9 | Selenite protects human endothelial cells from oxidatice damage and induces thioredoxin reductase显示文摘 | Miller S Walker SW Arthur JR | 2001 | Clin Sei2001，100，： | 1 |
| 10 | Posterior Transvertebral Osteotomy for Adult Thoracolumbar Kyphosis显示文摘 | Steven M. Lehmer Louis Keppler Robert S. Biscup Paul Enker Scot D. Miller Arthur D. Steffee | 1994 | Spine1994，，18： | 1 |
| 11 | Selenite protects human endothelial cells from oxidative damage and induces thioredoxin reduetase显示文摘 | Miller S Walker SW Arthur JR | 2001 | Clin Sei2001，100，5： | 1 |
| 12 | Toward a Concept of Constitutional Duty 显示文摘 | Arthur Selwyn Miller | 1968 | The Supreme Court Review1968，，： | 1 |
| 13 | Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults显示文摘 | Philip A Waller Pramod K. Gopal Gregory J Leyer Arthur C. Ouwehand Cheryl Reifer Morgan E. Stewart Larry E. Miller | 2011 | Scandinavian Journal of Gastroenterology2011，，9： | 1 |
| 14 | Selenoprotein expression in endothelial cells from different human vasculature and species 显示文摘 | Miller S Walker SW Arthur JR | 2002 | Biochem et Biophys Acta2002，，1： | 1 |
| 15 | Selenite protects human endothelial cells from oxidative damage and induces thioredoxin reductase显示文摘 | Miller S Walker S W Arthur J R | 2001 | Clin Sci (Colch)2001，100，5： | 1 |
| 16 | Selenite protects human endothelial cells from oxidative damage and induces thioredoxin reductase显示文摘 | MILLER S WALKER S W ARTHUR J R | 2001 | Clin Sci( Lond )2001，100，5： | 1 |
| 17 | Adequacy of early empiric antibiotic treatment and survival in severe sepsis: experience from the MONARCS trial显示文摘 | Mac Arthur RD Miller M Albertson T | 2004 | Clin Infect Dis2004，38，2： | 1 |
| 18 | Glaucoma Patients’ Assessment of Their Visual Function and Quality of Life显示文摘 | Henry D. Jampel Arthur Schwartz Irvin Pollack Donald Abrams Howard Weiss Rhonda Miller | 2002 | Journal of Glaucoma2002，，2： | 1 |
| 19 | Selenoprotein expression in endothelial cells from different human vasculature and species显示文摘 | Miller S Walker SW Arthur JR | 2002 | Biochim Biophys Acta2002，1588，1： | 1 |
| 20 | Contribution of GPR30 for 1,25 dihydroxyvitamin D 3 protection in EAE显示文摘 | Sandhya Subramanian Lisa M. Miller Marjorie R. Grafe Arthur A. Vandenbark Halina Offner | 2012 | Metabolic Brain Disease2012，，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员