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| 1 | Ultrasound probe pressure but not maternal Valsalva maneuver alters Doppler parameters during fetal middle cerebral artery Doppler ultrasonography显示文摘 | Yi‐MingSu Guo‐RongLv Xiao‐KangChen Shao‐HuiLi Hui‐TongLin | 2010 | Prenat Diagn (鈥?)2010，，12： | 1 |
| 2 | Application of acetylacetone chelation solid-phase extraction method to measurement of trace amounts of beryllium in milk by GFAAS显示文摘 | LI Chenchu KUO Mingsu | 2002 | Anal Sci2002，18，： | 1 |
| 3 | Comparison of outcomes between pure laparoscopic vs robot‐assisted laparoscopic radical prostatectomy: a study of comparative effectiveness based upon validated quality of life outcomes显示文摘 | Daniel L.Willis Mark L.Gonzalgo MichelleBrotzman ZhaoyongFeng BruceTrock Li‐MingSu | 2012 | BJU International2012，，6： | 1 |
| 4 | ROC曲线及Logistic回归评价肿瘤标志物在胃结肠肿瘤的诊断价值(英文)显示文摘Objective: The aim of the study was to evaluate the clinical significance of multiple tumor markers (CEA, AFP, CA72-4 and CA19-9) in patients with gastrocolic tumors by receiver operating characteristic (ROC) curve and stepwise logistic regression (LR) analysis. Methods: The serum concentrations of CEA, AFP, CA72-4 and CA19-9 were measured with electrochemiluminescence immunoassay in 126 patients with gastrocolic tumors, 137 patients with benign gastrocolic disorders and 109 healthy controls. The area under the ROC curve (AUC) of CEA, AFP, CA72-4 and CA19-9 and stepwise LR results were compared by sensitivity, specificity, Youden's index and positive likelihood ratio/negative likelihood ratio. Results: The levels of four tested tumor markers in patients with gastrocolic tumors were significantly higher than those in benign gastrocolic group and normal controls. In the benign gastrocolic group, the AUC from stepwise logistic regression was larger than the AUC of four tumor markers respectively. Sensitivity, Youden's index and positive likelihood ratio/negative likelihood ratio were the highest in the combination assay of CA72-4, CEA, and CA19-9, as compared with one of the tumor markers alone. Conclusion: The use of ROC established by LR analysis model improved the diagnostic accuracy of gastrocolic tumors. For the screening of gastrocolic tumors, the AUC value of the combination probability index (sensitivity and specificity) was significantly higher than the values of the different tumour markers. | Jinbo Liu Mingsu Zhou Yonglun Hang Meizhu Cai Min Song Ting Ye Kaizheng Wang | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，11： | 0 |
| 5 | A novel Bayesian network inference algorithm for integrative analysis of heterogeneous deep sequencing data显示文摘 | YiLiu #x0002A NanQiao #x0002A ShanshanZhu MingSu NaSun JeromeBoyd-Kirkup Jing-Dong JHan | 2013 | Cell Research2013，23，3： | 0 |
| 6 | The interaction between circadian rhythm and epilepsy显示文摘Evidence about the interaction between circadian rhythms(CR)and epilepsy has been expanded with the application of advanced detection technology.An adequate understanding of how circadian system and epilepsy interact with each other could contribute to more accurate seizure prediction as well as rapid development of potential treatment timed to specific phases of CR.In this review,we present the reciprocal relationship between CR and epileptic activities from aspects of sleep effect,genetic modulation and brain biochemistry.It has been found that sleep-wake patterns,circadian timing systems and multidien rhythms have essential roles in seizure activities and interictal epileptiform discharge(IED).For instance,specific distribution patterns of seizures and IED have been reported,i.e.,lighter non-rapid eye movement(NREM)sleep stage(stage 2)induces seizures while deeper NREM sleep stage(stage 3)activates IEDs.Furthermore,the epilepsy type,seizure type and seizure onset zone can significantly affect the rhythms of seizure occurrence.Apart from the common seizure types,several specific epilepsy syndromes also have a close correlation with sleep-wakefulness patterns.Sleep influences the epilepsy rhythm,and conversely,epilepsy alters the sleep rhythm through multiple pathways.Clock genes accompanied by two feedback loops of regulation have an important role in cortical excitability and seizure occurrence,which may be involved in the mTORopathy.The suprachiasmatic nuclei(SCN)has a rhythm of melatonin and cortisol secretion under the circadian pattern,and then these hormones can feed back into a central oscillator to affect the SCN-dependent rhythms,leading to variable but prominent influence on epilepsy.Furthermore,we discuss the precise predictive algorithms and chronotherapy strategies based on different temporal patterns of seizure occurrence for patients with epilepsy,which may offer a valuable indication for non-invasive closed-loop treatment system.Optimization of the time and dose of antiseizure medications,and resynchronization of disturbed CR(by hormone therapy,light exposure,ketogenic diet,novel small molecules)would be beneficial for epileptic patients in the future.Before formal clinical practice,future large-scale studies are urgently needed to assist prediction and treatment of circadian seizure activities and address unsolved restrictions. | Mingsu Liu Jing Ding Xin Wang | 2022 | Acta Epileptologica2022，5，3： | 0 |
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