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| 1 | The complete mitochondrial genome of the Chinese oak silkmoth, Antheraea pernyi (Lepidoptera: Saturniidae)显示文摘我们从中国橡树丝绸蛾决定了 mitogenome 的完全的核苷酸顺序, Antheraea pernyi (鳞翅目:Saturniidae ) 。15,566 bp 通报染色体为鳞翅类的 mitogenomes 包含不正常的基因组织和顺序。mitogenome 在已知的鳞翅类的 mitogenome 序列之中包含最低 A+T 内容(80.16%) 。一个不平常的特征比作为是更多的 T 的出现,与一在偏斜度(−0.021 ) 稍微否定,在主要染色体海滨的作文。所有编码蛋白质的基因被 ATN 鳕鱼 ons 开始,除了细胞色素 oxidase 子单元我,它被在另外的 lepidopterans 观察了的 TTAG 顺序建议。所有转移 RNA (tRNAs ) 有 mitochondrial tRNA 的典型四叶苜蓿形的立体道路交叉点结构,除了 tRNA 重量的单位 (AGN), 哪个不能形成稳定的茎环结构的 DHU 手臂。二与一段超过 50 bp 排列了顺序块, 90% 顺序身份在 Saturniidae 和 Bombycoidae 种类的 A+T 富有的区域被识别。 | Yanqun Liu Yuping Li Minhui Pan Fangyin Dai Xuwei Zhu Cheng Lu Zhonghuai Xiang | 2008 | Acta Biochimica et Biophysica Sinica2008，40，8： | 21 |
| 2 | Degradation of carbon tetrachloride in thermally activated persulfate system in the presence of formic acid显示文摘碳四氯化物(CT ) 的热地激活的 persulfate (PS ) 降级面对蚁的酸(FA ) 被调查。结果显示那 CT 降级跟随了零份订单运动模型,和公司 2- | Minhui XU Xiaogang GU Shuguang LU Zhouwei MIAO Xueke ZANG Xiaoliang WU Zhaofu QIU Qian SUI | 2016 | Frontiers of Environmental Science & Engineering2016，10，3： | 6 |
| 3 | Enhanced degradation of trichloroethene by calcium peroxide activated with Fe(III) in the presence of citric acid显示文摘由 Fe (III ) 的 Trichloroethene (TCE ) 降级 - 激活的钙过氧化物(CP ) 面对在水的答案的柠檬性的酸(CA ) 被调查。结果证明 CA 的存在由增加可溶的 Fe (III ) 的集中并且支持 H 2 O 2 产生。产生惊讶并且在 CP/Fe (III ) 和 CP/Fe (III ) 的 O 2-/CA 系统与化学探针被证实。激进的清除测试的结果证明那 TCE 降级主要是到期的指导氧化由惊讶,当 O 2- 加强了产生时惊讶由支持 Fe (III ) 在 CP/Fe (III )/CA 系统的转变。酸的 pH 条件为 TCE 降级是有利的,并且 TCE 降级率与增加 pH 减少了。Cl -, HCO 3-, 和腐殖的酸的存在(哈) 禁止的 TCE 降级到为 CP/Fe (III )/CA 系统的不同程度。Cl 生产的分析建议在 CP/Fe (III )/CA 系统的那 TCE 降级通过一个 dechlorination 过程发生了。在摘要,这研究提供了详细信息因为提高 CA 的 Fe (III ) 的申请激活钙过氧化物因为对待 TCE 污染了地下水。 | Xiang ZHANG Xiaogang GU Shuguang LU Zhouwei MIAO Minhui XU Xiaori FU Muhammad DANISH Mark L. BRUSSEAU Zhaofu QIU Qian SUI | 2016 | Frontiers of Environmental Science & Engineering2016，10，3： | 5 |
| 4 | BmCyclin B and BmCyclin B3 are required for cell cycle progression in the silkworm, Bombyx mori显示文摘Cyclin B is an important regulator of the cell cycle G2 to M phase transition. The silkworm genomic database shows that there are two Cyclin B genes in the silkworm (Bombyx mori), BmCyclin B and BmCyclin B3. Using silkworm EST data, the cyclin B3 (EU074796) gene was cloned. Its complete cDNA was 1665 bp with an ORF of 1536 bp derived from seven exons and six introns. The BmCyclin B3 gene encodes 511 amino acids, and the predicted molecular weight is 57.8 kD with an isoelectric point of 9.18. The protein contains one protein damage box and two cyclin boxes. RNA interference-mediated reduction of BmCyclin B and BmCyclin B3 expression induced cell cycle arrest in G2 or M phase in BmN-SWU1 cells, thus inhibiting cell proliferation. These results suggest that BmCyclin B and BmCyclin B3 are necessary for completing the cell cycle in silkworm cells. | PAN MinHui HONG KaiLi CHEN XiangYun PAN Chun CHEN XueMei KUANG XiuXiu LU Cheng | 2013 | Science China(Life Sciences)2013，56，4： | 1 |
| 5 | Degradation of carbon tetrachloride in aqueous solution in the thermally activated persulfate system 显示文摘 | Minhui Xu Xiaogang Gu Shuguang Lu | 2015 | Journal of Hazardous Materials2015，286，： | 1 |
| 6 | Inhibition of the maize salt overly sensitive pathway by ZmSK3 and ZmSK4显示文摘Soil salinity is a worldwide problem that adversely affects plant growth and crop productivity. The salt overly sensitive (SOS) pathway is evolutionarily conserved and essential for plant salt tolerance. In this study, we reveal how the maize shaggy/glycogen synthase kinase 3-like kinases ZmSK3 and ZmSK4, orthologs of brassinosteroid insensitive 2 in Arabidopsis thaliana, regulate the maize SOS pathway. ZmSK3 and ZmSK4 interact with and phosphorylate ZmSOS2, a core member of the maize SOS pathway. The mutants defective in ZmSK3 or ZmSK4 are hyposensitive to salt stress, with higher salt-induced activity of ZmSOS2 than that in the wild type. Furthermore, the Ca^(2+) sensors ZmSOS3 and ZmSOS3-like calcium binding protein 8 (ZmSCaBP8) activate ZmSOS2 to maintain Na^(+)/K^(+) homeostasis under salt stress and may participate in the regulation of ZmSOS2 by ZmSK3 and ZmSK4. These findings discover the regulation of the maize SOS pathway and provide important gene targets for breeding salt-tolerant maize. | Jianfang Li Xueyan Zhou Yan Wang Shu Song Liang Ma Qian He Minhui Lu Kaina Zhang Yongqing Yang Qian Zhao Weiwei Jin Caifu Jiang Yan Guo | 2023 | Journal of Genetics and Genomics2023，50，12： | 1 |
| 7 | Construction of a One-Vector Multiplex CRISPR/Cas9 Editing System to Inhibit Nucleopolyhedrovirus Replication in Silkworms显示文摘Recently the developed single guide(sg)RNA-guided clustered regularly interspaced short palindromic repeats/associated protein 9 nuclease(CRISPR/Cas9) technology has opened a new avenue for antiviral therapy. The CRISPR/Cas9 system uniquely allows targeting of multiple genome sites simultaneously. However, there are relatively few applications of CRISPR/Cas9 multigene editing to target insect viruses. To address the need for sustained delivery of a multiplex CRISPR/Cas9-based genome-editing vehicle against insect viruses, we developed a one-vector(pSL1180-Cas9-U6-sgRNA) system that expresses multiple sgRNA and Cas9 protein to excise Bombyx mori nucleopolyhedrovirus(BmNPV) in insect cells.We screened the immediate-early-1 gene(ie-1), the major envelope glycoprotein gene(gp64), and the late expression factor gene(lef-11), and identified multiple sgRNA editing sites through flow cytometry and viral DNA replication analysis. In addition, we constructed a multiplex editing vector(PSL1180-Cas9-sgIE1-sgLEF11-sgGP64, sgMultiple) to efficiently regulate multiplex gene-editing and inhibit BmNPV replication after viral infection. This is the first report of the application of a multiplex CRISPR/Cas9 system to inhibit insect virus replication. This multiplex system can significantly enhance the potential of CRISPR/Cas9-based multiplex genome engineering in insect virus. | Zhanqi Dong Qi Qin Zhigang Hu Peng Chen Liang Huang Xinling Zhang Ting Tian Cheng Lu Minhui Pan | 2019 | Virologica Sinica2019，34，4： | 1 |
| 8 | Ultrasound Elastography in the Differential Diagnosis of Benign and Malignant Cervical Lesions显示文摘 | Rong Lu Ying Xiao Minhui Liu otal | 2014 | J Ultrasound Med2014，33，： | 1 |
| 9 | Bee Sting-Inspired Inflammation-Responsive Microneedles for Periodontal Disease Treatment显示文摘Periodontal lesions are common and frustrating diseases that impact life quality.Efforts in this aspect aim at developing local drug delivery systems with better efficacy and less toxicity.Herein,inspired by the sting separation behavior of bees,we conduct novel reactive oxygen species(ROS)-responsive detachable microneedles(MNs)that carry antibiotic metronidazole(Met)for controllable periodontal drug delivery and periodontitis treatment.Benefiting from the needle-base separation ability,such MNs can penetrate through the healthy gingival to reach the gingival sulcus's bottom while offering minimal impact to oral function.Besides,as the drug-encapsulated cores were protected by poly(lactic-co-glycolic acid)(PLGA)shells in MNs,the surrounding normal gingival tissue is not affected by Met,resulting in excellent local biosafety.Additionally,with the ROS-responsive PLGA-thioketal-polyethylene glycol MN tips,they can be unlocked to release Met directly around the pathogen under the high ROS in the periodontitis sulcus,bringing about improved therapeutic effects.Based on these characteristics,the proposed bioinspired MNs show good therapeutic results in treating a rat model with periodontitis,implying their potential in periodontal disease. | Chuanhui Song Xiaoxuan Zhang Minhui Lu Yuanjin Zhao | 2023 | Research2023，，4： | 0 |
| 10 | Developing hierarchical microneedles for biomedical applications显示文摘As a new kind of microcarrier device,microneedles are featured by micrometer needle arrays with an overall size in the centimeter scale.Due to the needle shape and the micron size,microneedles can penetrate the skin without harming nerves and blood vessels,which causes many advantages such as minimally invasive,safe and convenient.The past few decades have witnessed a great leap in microneedles research.The main materials of microneedles have changed from metal and ceramic to polymers with more complex functions,and the optimiza-tion of materials and preparation strategies has led to a greater variety of microneedle styles.Among them,the construction or combination of smaller size structures or materials on microneedles to fabricate hierarchical mi-croneedles is a major research hotspot.Here,we present the recent research progress of hierarchical microneedles for biomedicine.We begin by discussing the fabrication strategies of hierarchical microneedles,including main-stream casting and coating methods based on microneedle molds and three dimensions(3D)printing methods.We then expand the discussion from the hierarchical microneedles with porous structure to those composited with nanomaterials.Eventually,we have a discussion about the research progress of hierarchical microneedles in the area of biomarkers detection and transdermal drug delivery,as well as its future development direction. | Minhui Lu Xiaoxuan Zhang Zhiqiang Luo Yuanjin Zhao | 2023 | Engineered Regeneration2023，4，3： | 0 |
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