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| 1 | Transcranial magnetic stimulation in animal models of neurodegeneration显示文摘Brain stimulation techniques offer powerful means of modulating the physiology of specific neural structures. In recent years, non-invasive brain stimulation techniques, such as transcranial magnetic stimulation(TMS) and transcranial direct current stimulation, have emerged as therapeutic tools for neurology and neuroscience. However, the possible repercussions of these techniques remain unclear, and there are few reports on the incisive recovery mechanisms through brain stimulation. Although several studies have recommended the use of non-invasive brain stimulation in clinical neuroscience, with a special emphasis on TMS, the suggested mechanisms of action have not been confirmed directly at the neural level. Insights into the neural mechanisms of non-invasive brain stimulation would unveil the strategies necessary to enhance the safety and efficacy of this progressive approach. Therefore, animal studies investigating the mechanisms of TMSinduced recovery at the neural level are crucial for the elaboration of non-invasive brain stimulation. Translational research done using animal models has several advantages and is able to investigate knowledge gaps by directly targeting neuronal levels. In this review, we have discussed the role of TMS in different animal models, the impact of animal studies on various disease states, and the findings regarding brain function of animal models after TMS in pharmacology research. | Mohammad Uzair Turki Abualait Muhammad Arshad Woo-Kyoung Yoo Ali Mir Reem Fahd Bunyan Shahid Bashir | 2022 | Neural Regeneration Research2022，17，2： | 4 |
| 2 | Fault diagnosis using noise modeling and a new artificial immune system based algorithm显示文摘A new fault classification/diagnosis method based on artificial immune system(AIS) algorithms for the structural systems is proposed. In order to improve the accuracy of the proposed method, i.e., higher success rate, Gaussian and non-Gaussian noise generating models are applied to simulate environmental noise. The identification of noise model, known as training process, is based on the estimation of the noise model parameters by genetic algorithms(GA) utilizing real experimental features. The proposed fault classification/diagnosis algorithm is applied to the noise contaminated features. Then, the results are compared to that obtained without noise modeling. The performance of the proposed method is examined using three laboratory case studies in two healthy and damaged conditions. Finally three different types of noise models are studied and it is shown experimentally that the proposed algorithm with non-Gaussian noise modeling leads to more accurate clustering of memory cells as the major part of the fault classification procedure. | Farshid Abbasi Alireza Mojtahedi Mir Mohammad Ettefagh | 2015 | Earthquake Engineering and Engineering Vibration2015，14，4： | 3 |
| 3 | A Preliminary Study on Combination Therapy of Artemisinin Dimer Oxime and Topotecan against Nonsmall Cell Lung Cancer in Mice显示文摘Background: Artemisinin dimer oxime – dimer molecule synthesized from artemisinin possesses high bioavailability and marked in vitro anticancer activities against solid tumor?derived cell lines, endothelial cell proliferation, migration, and angiogenic processes. Numerous murine models have been developed to study human cancer. The most widely used models are the human tumor xenograft mouse model. Materials and Methods: In this study, human tumor cells(NCI?H640, 1 × 107 in 100 μL) are implanted subcutaneously, or 1 × 107 in 50 μL in the thoracic cavity, in athymic nude mice(nu/nu). The implanted cells were allowed to grow for 10 days before initiation of drug treatment(dimer oxime and topotecan, ip). Tumor volume and thoracic/body weight ratio were recorded. Results: We successfully established subcutaneous and thoracic xenografts with human nonsmall cell lung cancer cell line xenografts in athymic nude mice in only 10 days. Using these models, we attempted treatment of xenografts with topotecan – a known anticancer drug and artemisinin dimer oxime or combination of these two drugs. Combination therapy showed a significant reduction in tumor volume and tumor/body weight. Treatments with combination of topotecan and dimer oxime resulted in the reduced mortality rates in comparison with untreated mice. Conclusions: Xenograft tumor models are useful for preclinical screening of new pharmacophores. From this preliminary study, it appears that combination of dimer oxime and topotecan may be used as chemotherapeutic agents against nonsmall cell lung cancer. Further studies are needed to evaluate other combination treatment regimens as well as the mechanism(s) of action. | Mohammad K.Ashfaq Mohamed Sadek Abdel-Bakky Mir Tahir Maqbool Waseem Gul Mahmoud A.ElSohly | 2018 | World Journal of Traditional Chinese Medicine2018，4，1： | 3 |
| 4 | Combination of sensitivity and uncertainty analyses for sediment transport modeling in sewer pipes显示文摘Mitigation of sediment deposition in lined open channels is an essential issue in hydraulic engineering practice.Hence,the limiting velocity should be determined to keep the channel bottom clean from sediment deposits.Recently,sediment transport modeling using various artificial intelligence(AI)techniques has attracted the interest of many researchers.The current integrated study highlights unique insight for modeling of sediment transport in sewer and urban drainage systems.A novel methodology based on the combination of sensitivity and uncertainty analyses with a machine learning technique is proposed as a tool for selection of the best input combination for modeling process at non-deposition conditions of sediment transport.Utilizing one to seven dimensionless parameters,127 models are developed in the current study.In order to evaluate the different parameter combinations and select the training and testing data,four strategies are considered.Considering the densimetric Froude number(Fr)as the dependent parameter,a model with independent parameters of volumetric sediment concentration(CV)and relative particle size(d/R)gave the best results with a mean absolute relative error(MARE)of 0.1 and a root means square error(RMSE)of 0.67.Uncertainty analysis is applied with a machine learning technique to investigate the credibility of the proposed methods.The percentage of the observed sample data bracketed by 95%predicted uncertainty bound(95PPU)is computed to assess the uncertainty of the best models. | Isa Ebtehaj Hossein Bonakdari Mir Jafar Sadegh Safari Bahram Gharabaghi Amir Hossein Zaji Hossien Riahi Madavar Zohreh Sheikh Khozani Mohammad Sadegh Es-haghi Aydin Shishegaran Ali Danandeh Mehr | 2020 | International Journal of Sediment Research2020，35，2： | 2 |
| 5 | Toxicity assessment of polyethylene microplastics in combination with a mix of emerging pollutants on Physalaemus cuvieri tadpoles显示文摘Studies in recent years have shown that aquatic pollution by microplastics(MPs)can be considered to pose additional stress to amphibian populations.However,our knowledge of how MPs affect amphibians is very rudimentary,and even more limited is our understanding of their effects in combination with other emerging pollutants.Thus,we aimed to evaluate the possible toxicity of polyethylene MPs(PE-MPs)(alone or in combination with a mix of pollutants)on the health of Physalaemus cuvieri tadpoles.After 30 days of exposure,multiple biomarkers were measured,including morphological,biometric,and developmental indices,behavioral parameters,mutagenicity,cytotoxicity,antioxidant and cholinesterase responses,as well as the uptake and accumulation of PE-MPs in animals.Based on the results,there was no significant change in any of the parameters measured in tadpoles exposed to treatments,but induced stress was observed in tadpoles exposed to PE-MPs combined with themixture of pollutants,reflecting significant changes in physiological and biochemical responses.Through principal component analysis(PCA)and integrated biomarker response(IBR)assessment,effects induced by pollutants in each test group were distinguished,confirming that the exposure of P.cuvieri tadpoles to the PE-MPs in combination with a mix of emerging pollutants induces an enhanced stress response,although the uptake and accumulation of PE-MPs in these animalswas reduced.Thus,our study provides newinsight into the danger to amphibians of MPs coexisting with other pollutants in aquatic environments. | Amanda Pereira da Costa Araújo Thiarlen Marinho da Luz Mohamed Ahmed Ibrahim Ahmed Mir Mohammad Ali Md.Mostafizur Rahman Bojan Nataraj Daniela de Melo e Silva DamiàBarceló Guilherme Malafaia | 2023 | Journal of Environmental Sciences2023，，5： | 2 |
| 6 | Energy Harvesting From Sea Waves With Consideration of Airy and JONSWAP Theory and Optimization of Energy Harvester Parameters显示文摘为在海驱动低力量的电子设备的新方法之一是收获系统的一个波浪精力。在这个方法,压电的材料被采用把海波浪的机械精力变换成电能。这个方法的优点基于避免控告系统的一节电池。研究在然而,就与随机的 JONSWAP 波浪理论收获的精力而言从海波浪收获的精力上被做了,然后决定收获的精力的最佳价值是新的。这份报纸由实现 JONSWAP 波浪模型做那,计算生产力量,并且写实地证明产量力量与更简单的空气的波浪模型比较被减少。另外,精力 harvester 系统的参数用一个模仿的退火的算法被优化,产出增加的生产力量。 | Hadi Mirab Reza Fathi Vahid Jahangiri Mir Mohammad Ettefagh Reza Hassannejad | 2015 | Journal of Marine Science and Application2015，14，4： | 2 |
| 7 | Thermal and mechanical properties of polyurethane rigid foam/modified nanosilica composite显示文摘 | Mir Mohammad AlaviNikje Zahra MazaheriTehrani | 2010 | Polym Eng Sci2010，，3： | 1 |
| 8 | A microwave assisted oxidation of benzaldehydes under solvent-free condition using oxone/wet-alumina,phosphorus显示文摘 | Nikje Mir M Alavi Bigdeli Mohammad | 2004 | Sulfur and Silicon and the Related Elements2004，179，7： | 1 |
| 9 | Issues in reducing the cogging torque of mass-produced permanent magnet brushless DC motor显示文摘 | Mohammad S Islam Mir S Sebastian T | 2004 | IEEE Transactions on Industry Applications2004，40，3： | 1 |
| 10 | Determination of phthalate esters in cow milk samples using dispersive liquid-liquid microextraction coupled with gas chromatography followed by flame ionization and mass spectrometric detection显示文摘 | MIR A F DJAVANSHIR D MOHAMMAD | 2012 | J Sep Sci2012，35，： | 1 |
| 11 | Preparation and characterization of insulin nanoparticles using chitosan and Arabic gum with ionic gelation method显示文摘 | Mohammad Reza Avadi Assal Mir Mohammad Sadeghi Nasser Mohammadpour | | 0，，： | 1 |
| 12 | Solubilization of triphenylamine, triphenylphosphine, triphenylphosphineoxide and triphenylmethanol in single and binary surfactant systems显示文摘 | Mohammad Amin Mir Oyais Ahmad Chat Muzaffar Hussain Najar Mohammad Younis Aijaz Ahmad Dar Ghulam Mohammad Rather | 2011 | Journal of Colloid And Interface Science2011，，： | 1 |
| 13 | Issues in Reducing the Cogging Torque of Mass - Produced Permanent - Magnet Brushless DC Motor显示文摘 | Mohammad S Islam Sayeed Mir Tomy Sebastian | 2004 | IEEE TRANSACTIONS ON INDUSTRY APPLICATIONS2004，40，3： | 1 |
| 14 | Crack detection in beam-like structures using genetic algorithms显示文摘 | Mohammad-Taghi Vakil-Baghmisheh Mansour Peimani Morteza Homayoun Sadeghi Mir Mohammad Ettefagh | 2007 | Applied Soft Computing Journal2007，，2： | 1 |
| 15 | Preparation and appli- cation of glycolysed polyurethane intergral skin foams recy- clate from automotive wastes显示文摘 | ALAVI NIKJE Mir Mohammad HAGHSHENAS Mos- lem GARMARUDI Amir Bagheri | 2006 | Polymer Bulletin2006，56，： | 1 |
| 16 | Analyses of the effect of seismic behavior of shallow tunnels in lique- fiable grounds 显示文摘 | Azadi M Mir Mohammad Hosseini S M | 2010 | Tunnelling and Underground Space Technology2010，25，5： | 1 |
| 17 | The uplifting behavior of shallow tunnels within the liquefiable soils under cyclic loadings显示文摘 | M. Azadi S.M. Mir Mohammad Hosseini | 2009 | Tunnelling and Underground Space Technology incorporating Trenchless Technology Research2009，，2： | 1 |
| 18 | Design of a fuzzy model based on vibration signal analysis to auto-detect the gear faults 显示文摘 | Mohammad Hashemi Mir Saeed Safizadeh | 2013 | Industrial Lubrication and Tribology2013，65，3： | 1 |
| 19 | Synthesis and characterization of waterborne polyurethane-chitosan nanocomposites显示文摘 | MOHAMMAD ALAVI Nikje Mir TEHRANI Zahra Mazathen | 2010 | Polymer-plastics Technology and Engineering2010，49，8： | 1 |
| 20 | Effects of neurofeedback on the short-term memory and continuous attention of patients with moderate traumatic brain injury: A preliminary randomized controlled clinical trial显示文摘PurposeThere 是证明 neurofeedback 治疗(NFT ) 能在有创伤的大脑损害(TBI ) 的顾客是有效的一些研究历史。然而,使随机化控制临床的试用仍然作为一种标准选择为这治疗的评估被需要。这初步的研究被瞄准用使随机化的控制临床的试用( RCT )与中等 TBI 在连续注意( CA )和顾客的短期的记忆( STM )上评估 NFT 的效果 .MethodsIn 这初步的 RCT ,有中等 TBI 的十七个合格病人随机在二干预和控制组被分配。所有病人为分别地,以后在包括的时候两个都使用视觉连续注意测试和 Wechsler 记忆 scale-4th 编辑(WMS-IV ) 测试到工程和四个星期的 CA 和 STM 被评估。干预组整个开始的四个星期参予了 NFT 的 20 个会议。相反地,控制组在干预组从第五个星期参予了一样的 NF 会话到第八星期 project.ResultsEight 题目,在控制组的五个题目完成了学习。参加者年龄的平均数和标准差是(26.75 吗?? | Reza Rostami Payman Salamati Kourosh Karimi Yarandi Alireza Khoshnevisan Soheil Saadat Zeynab Sadat Kamali Somaie Ghiasi Atefeh Zaryabi Seyed Shahab Ghazi Mir Saeid Mehdi Arjipour Mohammad Saeid Rezaee-Zavareh Vafa Rahimi-Movaghar | 2017 | Chinese Journal of Traumatology2017，20，5： | 1 |
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