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| 1 | Outcomes of preoperative chemoradiotherapy followed by surgery in patients with unresectable locally advanced sigmoid colon cancer显示文摘Background: Complete resection of locally advanced sigmoid colon cancer(LASCC) is sometimes difficult. Patients with LASCC have a dismal prognosis and poor quality of life, which has encouraged the evaluation of alternative multimodality treatments. This prospective study aimed to assess the feasibility and efficacy of neoadjuvant chemora?diotherapy(neo CRT) followed by surgery as treatment of selected patients with unresectable LASCC.Methods: We studied the patients with unresectable LASCC who received neo CRT followed by surgery between October 2010 and December 2012. The neoadjuvant regimen consisted of external?beam radiotherapy to 50 Gy and capecitabine?based chemotherapy every 3 weeks. Surgery was scheduled 6–8 weeks after radiotherapy.Results: Twenty?one patients were included in this study. The median follow?up was 42 months(range, 17–57 months). All patients completed neo CRT and surgery. Resection with microscopically negative margins(R0 resection) was achieved in 20 patients(95.2%). Pathologic complete response was observed in 8 patients(38.1%). Multivisceral resection was necessary in only 7 patients(33.3%). Two patients(9.5%) experienced grade 2 postopera?tive complications. No patients died within 30 days after surgery. For 18 patients with pathologic M0(yp M0) disease, the cumulative probability of 3?year local recurrence?free survival, disease?free survival and overall survival was 100.0%, 88.9% and 100.0%, respectively. For all 21 patients, the cumulative probability of 3?year overall survival was 95.2% and bladder function was well preserved.Conclusion: For patients with unresectable LASCC, preoperative chemoradiotherapy and surgery can be performed safely and may result in an increased survival rate. | Bo Qiu Pei-Rong Ding Ling Cai Wei-Wei Xiao Zhi-Fan Zeng Gong Chen Zhen-Hai Lu Li-Ren Li Xiao-Jun Wu Rene-Olivier Mirimanoff Zhi-Zhong Pan Rui-Hua Xu Yuan-Hong Gao | 2016 | Chinese Journal of Cancer2016,35,10: | 14 |
| 2 | High-grade gliomas: reality and hopes显示文摘In this issue of the Chinese Journal of Cancer, European experts review current standards, trends, and future prospects in the difficult domain of high-grade glioma. In all fields covered by the different authors, the progress has been impressive. For example, discoveries at the molecular level have already impacted imaging, surgery, radiotherapy, and systemic therapies, and they are expected to play an increasing role in the management of these cancers. The European Organization for Research and Treatment of Cancer(EORTC) has pioneered new treatment strategies and contributed to new standards. The articles in this issue will cover basic molecular biological principles applicable today, novel surgical approaches, innovations in radiotherapy planning and delivery, evidence-based standards for radiotherapy alone or combined with chemotherapy, current standards and novel approaches for systemic treatments, and the important but often neglected field of health-related quality of life. Despite the advances described in these articles, the overall prognosis of high-grade glioma, especially glioblastoma, remains poor, and more research is needed to address this problem. | René-Olivier Mirimanoff | 2014 | Chinese Journal of Cancer2014,33,1: | 6 |
| 3 | Meningioma:analysis of recurrence and progression following neurosurgical resection显示文摘 | Mirimanoff RO Dosoretz DE Linggood RM | 1985 | J Neurosurg1985,62,1: | 1 |
| 4 | New radiotherapy technologies for meni ngiomas:3D conformal radiotherapy? Radio surgery? Stereo tactic radiotherapy? Intensity-modulated radiotherapy? Proton beam rad iotherapy?Spot scanning proton radiation therapy… or nothing at all? 显示文摘 | Rene'-Olivier Mirimanoff | 2004 | Radiotherapy and Oncology2004,71,3: | 1 |
| 5 | Meningioma: analysis of recurrence and progression following neurosurgical resection 显示文摘 | Mirimanoff RO Dosoretz DE linggood RM | 1985 | J Neurosurg1985,68,: | 1 |
| 6 | Prostate cancer:On the road of progress显示文摘In Europe,prostate cancer(PCa)is the most frequently diagnosed cancer in men with an estimated 416000 new cases and the third leading cause of cancer death with 92000 deaths in 2012[1].In China,based on 177 of 234 cancer registries,PCa was the 7th most frequent neoplasm in men,with 49000 new cases in 2011[2].Of course the variability of the incidence of PCa has many causes,including environmental,dietary,lifestyle factors or genetic risks,with the well-known example of the higher incidence in African-American men compared to that of Caucasian men in the United States. | Michel Bolla René-Olivier Mirimanoff | 2019 | Asian Journal of Urology2019,6,2: | 1 |
| 7 | Radiotherapy in low-grade gliomas:Cons显示文摘 | Mirimanoff R O Stupp R | 2003 | Semin Oncol2003,30,619: | 1 |
| 8 | Meningioma:Analysis of recurrence and progression following neurosurgicalre section显示文摘 | Mirimanoff RO Dosoretz DE Linggood RM | 1985 | J Neurosurg1985,62,1: | 1 |
| 9 | Radiotherapy and temozolomide for newly diagnosed glioblastoma:recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase Ⅲ randomized trial显示文摘 | MIRIMANOFF R O GORLIA T MASON W | 2006 | J Clin Oncol2006,24,16: | 1 |
| 10 | Progress in radio-oncology 显示文摘 | Mirimanoff RO | 1992 | Rev Med Suisse Romande1992,112,3: | 1 |
| 11 | Radiotherapy of choroidal metastases 1 This paper was partially presented at the ECCO-8 conference, Paris, France (30 October 1995). 1显示文摘 | Anna Rosset Leonidas Zografos Philippe Coucke May Monney René O Mirimanoff | 1998 | Radiotherapy and Oncology1998,,3: | 1 |
| 12 | Early nutritional intervention in oropharyngeal cancer patients undergoing radiotherapy显示文摘 | Marie-Astrid Piquet Mahmut Ozsahin Isabelle Larpin Abderrahim Zouhair Pauline Coti May Monney Philippe Monnier René-Olivier Mirimanoff Michel Roulet | 2002 | Supportive Care in Cancer2002,,6: | 1 |
| 13 | Meningioma: analysis of recurrence and progression following neurosurgical resection 显示文摘 | Mirimanoff RO Dosoretz DE Linggood RM | 1985 | J Neurosurg1985,62,: | 1 |
| 14 | Meningioma:analysis of recurrence and progression following neurosurgical resection显示文摘 | Mirimanoff RO Dosoretz DE Linggood RM | 1985 | J Neurosurg1985,62,: | 1 |
| 15 | Meningioma:Analysis of recurrence and progression following neurosurgical resection 显示文摘 | MIRIMANOFF R O DOSOVETZ D E LINGGOOD R M | 1987 | J Neurosurg1987,62,: | 1 |
| 16 | Rapidly alternating combination of cisplatin based chemotherapy and hypcrfractionated accelerated radiotherapy in split course for stage Ⅲ a and Ⅲ b nonsmall cell lung cancer: results of a phase Ⅰ /Ⅱ study by the GOTHA Group显示文摘 | Alberto P Mirimanoff RO Mermillod B | 1995 | Eur J Cancer1995,31,: | 1 |
| 17 | Radiotherapy and te- mozolomide for newly diagnosed gliohlastoma: reeursive parti- tioning analysis of the EORTC 26981/22981-NCIC CE3 phaseⅢ randomized trial显示文摘 | Mirimanoff RO Gorlia T Mason W | 2006 | J Clin Oneol2006,24,16: | 1 |
| 18 | Meningioma:analysis of recurrence and progression following neurosurgicalresection显示文摘 | Mirimanoff BO Dosoretz DE Linggood RM | 1985 | J Neurosurg1985,62,1: | 1 |
| 19 | Alternating radiotherapy and chemotherapy for inoperable Stage Ⅲ non-small-cell lung cancer: long-term results of two Phase Ⅱ GOTHA trials 显示文摘 | Mirimanoff RO Moro D Bolla M | 1998 | Int J Radiat Oncol Biol Phys1998,42,3: | 1 |
| 20 | Meningioma analysis of recurrence and progression following neurosurgical resection显示文摘 | Mirimanoff RO Dosoretz DE Linggood RM | 1995 | Neurosurgery1995,62,1: | 1 |