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| 1 | A deep learning-enabled portable imaging flow cytometer for cost-effective, highthroughput, and label-free analysis of natural water samples显示文摘We report a deep learning-enabled field-portable and cost-effective imaging flow cytometer that automatically captures phase-contrast color images of the contents of a continuously flowing water sample at a throughput of 100 mL/h.The device is based on partially coherent lens-free holographic microscopy and acquires the diffraction patterns of flowing micro-objects inside a microfluidic channel.These holographic diffraction patterns are reconstructed in real time using a deep learning-based phase-recovery and image-reconstruction method to produce a color image of each micro-object without the use of external labeling.Motion blur is eliminated by simultaneously illuminating the sample with red,green,and blue light-emitting diodes that are pulsed.Operated by a laptop computer,this portable device measures 15.5 cm×15 cm×12.5 cm,weighs 1 kg,and compared to standard imaging flow cytometers,it provides extreme reductions of cost,size and weight while also providing a high volumetric throughput over a large object size range.We demonstrated the capabilities of this device by measuring ocean samples at the Los Angeles coastline and obtaining images of its micro-and nanoplankton composition.Furthermore,we measured the concentration of a potentially toxic alga(Pseudo-nitzschia)in six public beaches in Los Angeles and achieved good agreement with measurements conducted by the California Department of Public Health.The cost-effectiveness,compactness,and simplicity of this computational platform might lead to the creation of a network of imaging flow cytometers for largescale and continuous monitoring of the ocean microbiome,including its plankton composition. | Zoltán Gӧrӧcs Miu Tamamitsu Vittorio Bianco Patrick Wolf Shounak Roy Koyoshi Shindo Kyrollos Yanny Yichen Wu Hatice Ceylan Koydemir Yair Rivenson Aydogan Ozcan | 2018 | Light(Science & Applications)2018，7，1： | 14 |
| 2 | Parallel geneticalgorithm for service restoration in electric power distributionsystem显示文摘 | FUKUYAMA Y CHIANG H D MIU K N | 1996 | Electrical Power&Energy Systems1996，18，2： | 1 |
| 3 | Switch placement to improve system reliability for radial distribution systems with distributed ge-neration 显示文摘 | MAO Yiming MIU K N | 2003 | IEEE Trans on Power Systems2003，18，4： | 1 |
| 4 | Switch placement to improve system reliability for radial distribution systems with distributed generation显示文摘 | Yiming M Miu K N | 2003 | IEEE Transactions on Power Systems2003，18，4： | 1 |
| 5 | Switch Placement to Improve Sys- tem Reliability for Radial Distribution Systems with Distribu- ted Generation显示文摘 | MAO Yiming MIU K N | 2003 | IEEE Transactions on Power Systems2003，18，4： | 1 |
| 6 | Fast service restoration for large-scaled distribution systems with priority customer and constraints显示文摘 | Miu K N Chiang H D Yuan B | 1998 | IEEE Transactions on Power Systems1998，13，3： | 1 |
| 7 | Predicting unstable modes in power systems:theory and computations显示文摘 | Chiang H D Tong J Z Miu K N | 1993 | IEEE Trans on Power Systems1993，8，4： | 1 |
| 8 | Switch placement to improve system reliability for radial distribution systems with distributed generation 显示文摘 | Mao Yiming Miu K N | 2003 | IEEE Transactions on Power Systems2003，18，10： | 1 |
| 9 | Capacitor placeme-nt,replacement and control in large-scale distribution systems by a GA-based two-stage algorithm显示文摘 | Miu K N Chiang H D Darling G | 1997 | IEEE Trans on Power Systems1997，12，3： | 1 |
| 10 | Capacitor placement and real time control in large scale unbalanced distribution systems:loss reduction formula,problem formulation,solution methodology and mathematics justification显示文摘 | Wang Jincheng Chang H D Miu K N | 1997 | IEEE Trans on Power Delivery1997，12，2： | 1 |
| 11 | Fibrosing colonopathy revealing cystic fibrosis in a neonate before any pancreatic enzyme supplementation显示文摘 | Florescu P Miu N | 2002 | J Pediatr Gastroenterol Nutr2002，35，3： | 1 |
| 12 | Electric distribution system load capability: problems formulation, solution algorithm, and numerical results 显示文摘 | Miu K N Chiang H D | 2000 | IEEETrans onPower Delivery2000，15，1： | 1 |
| 13 | Capacitor placement and real time control inlarge-scale unbalanced distribution systems: Numerical studies显示文摘 | Wang J C Chiang H D Miu K N | 1997 | IEEE Transactions onPower Delivery1997，12，2： | 1 |
| 14 | Capacitor placement,replacement and control in large-scale distribution system by a GA-based two-stage algorithm显示文摘 | Miu K N Chiang Hsiao-Dong Daring G | 1997 | IEEE Trans on Power Systems1997，12，3： | 1 |
| 15 | Fast Service Restoration for Large-scale Distribution Systems with Priority Customers and Constraints 显示文摘 | Miu K N Chiang H D Yuan B | 1998 | IEEE Trans on Power Systems1998，13，3： | 1 |
| 16 | Fast service restoration for large-scale distribution systems with priority customers and con- straints显示文摘 | Miu K N Chiang H D Bentao Y | 1998 | lEEETransonPowersystems1998，13，3： | 1 |
| 17 | Switch placement to im- prove system reliability for radial distribution sys- tems with distributed generation显示文摘 | Mao Yiming Miu K N | 2003 | IEEE Trans on Power Systems2003，18，4： | 1 |
| 18 | Switch placement to improve system reliability for radial distribution systems with distributed generation显示文摘 | Mao Y Miu K N | 2003 | IEEE Transactions on Power Systems2003，18，4： | 1 |
| 19 | Switch placement to improve system reliability for radial distribution systems with distributed generation显示文摘 | MAO Y MIU K N | 2003 | IEEE Transactions on Power Systems2003，18，4： | 1 |
| 20 | Capacitor placement and real time control in large scale unbalanced distribution systems:loss reduction formula,problem formulation,solution methodology and mathematics justification显示文摘 | WANG Jin-cheng CHIANG Hsiao-dong MIU K N | 1997 | IEEE Trans on Power Delivery1997，12，2： | 1 |
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