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| 1 | Adverse events with bismuth salts for Helicobacter pylori eradication:Systematic review and meta-analysis显示文摘AIM: To assess the safety of bismuth used in Helico- bacter pylori (H pylori) eradication therapy regimens. METHODS: We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled tri- als comparing bismuth with placebo or no treatment, or bismuth salts in combination with antibiotics as part of eradication therapy with the same dose and duration of antibiotics alone or, in combination, with acid suppres- sion. Total numbers of adverse events were recorded. Data were pooled and expressed as relative risks with 95% confidence intervals (CI). RESULTS: We identified 35 randomised controlled tri- als containing 4763 patients. There were no serious adverse events occurring with bismuth therapy. There was no statistically significant difference detected in total adverse events with bismuth [relative risk (RR) = 1.01; 95% CI: 0.87-1.16], specific individual adverse events, with the exception of dark stools (RR = 5.06; 95% CI: 1.59-16.12), or adverse events leading to withdrawal of therapy (RR = 0.86; 95% CI: 0.54-1.37). CONCLUSION: Bismuth for the treatment of H pylori is safe and well-tolerated. The only adverse event oc- curring significantly more commonly was dark stools. | Alexander C Ford Peter Malfertheiner Monique Giguère José Santana Mostafizur Khan Paul Moayyedi | 2008 | World Journal of Gastroenterology2008，14，48： | 62 |
| 2 | 胃癌预防亚太地区共识指南显示文摘背景与目的:胃癌是亚太地区的主要健康负担之一,但对其预防策略尚缺乏共识。本共识会议旨在评价预防胃癌的策略。方法:多学科专家组应用德尔菲(Delphi)法制订共识条文,提呈相关数据,对证据等级、推荐强度以及共识水平予以分级。结果:幽门螺杆菌(H.pylori)感染是非贲门胃腺癌必要但非充分的致病因子。盐的高摄入与胃癌强烈相关。新鲜果蔬对胃癌具有预防作用,但维生素和其他饮食补充并不能预防胃癌。H.pylori感染中的宿主-细菌相互作用导致不同类型的胃炎和胃酸分泌,从而决定疾病结局。胃癌阳性家族史是一个重要的危险因素。低血清胃蛋白酶原反映胃萎缩程度,可作为检出胃癌高危人群的标志物。H.pylori筛查和治疗被推荐作为减少高危人群胃癌危险性的一种策略,该策略在萎缩性胃炎发生前实施最为有效,但并不排除对胃癌高危人群的内镜监测。对胃癌低危人群不推荐行H.pylori筛查。H.pylori感染的一线治疗应遵循国家治疗指南。结论:高危人群中H.pylori筛查和根除策略可能会减少胃癌的发生率,本共识根据现有证据予以推荐。 | Kwong Ming Fock Nick Talley Paul Moayyedi Richard Hunt Takeshi Azuma Kentaro Sugano Shu Dong Xiao Shiu Kum Lam Khean Lee Goh Tsutomu Chiba Naomi Uemura Jae G Kim Nayoung Kim Tiing Leong Ang Varocha Mahachai Hazel Mitchell Abdul Aziz Rani Jyh Ming Liou Ratha-korn Vilaichone Jose Sollanor 钱本余 | 2008 | 胃肠病学2008，13，4： | 37 |
| 3 | Genetic Risk Factors for Post-Infectious Irritable Bowel Syndrome Following a Waterborne Outbreak of Gastroenteritis显示文摘 | Alexandra–Chloé Villani Mathieu Lemire Marroon Thabane Alexandre Belisle Geneviève Geneau Amit X. Garg William F. Clark Paul Moayyedi Stephen M. Collins Denis Franchimont John K. Marshall | 2010 | Gastroenterology2010，，4： | 4 |
| 4 | Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial显示文摘 | Paul Moayyedi Michael G. Surette Peter T. Kim Josie Libertucci Melanie Wolfe Catherine Onischi David Armstrong John K. Marshall Zain Kassam Walter Reinisch Christine H. Lee | 2015 | Gastroenterology2015，，： | 3 |
| 5 | Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome: Systematic Review and Meta-analysis显示文摘 | Alexander C. Ford Brennan M.R. Spiegel Nicholas J. Talley Paul Moayyedi | 2009 | Clinical Gastroenterology and Hepatology2009，，12： | 2 |
| 6 | Limited Value of Alarm Features in the Diagnosis of Upper Gastrointestinal Malignancy: Systematic Review and Meta-analysis显示文摘 | Nimish Vakil Paul Moayyedi M. Brian Fennerty Nicholas J. Talley | 2006 | Gastroenterology2006，，2： | 2 |
| 7 | Helicobacter pylori public health implications显示文摘 | Moayyedi P Hunt RH | 2004 | Helicobacter2004，9，1： | 1 |
| 8 | Helicobacter pylori eradication does not exacerbate reflux symptoms in gastroeso- phageal reflux disease显示文摘 | Moayyedi P Bardhan C Young L | 2001 | Gastroenterology2001，121，5： | 1 |
| 9 | Rome Ⅲ criteria for functional gastrointestinal disorders:too much overlap to be useful?显示文摘 | Ford AC Morgan D Moayyedi P | | Gut0，60，1： | 1 |
| 10 | American gastroenterological association technical review on the evaluation of dyspepsia 显示文摘 | Talley NJ Vakil NB Moayyedi P | 2005 | Gastroenterology2005，129，： | 1 |
| 11 | Limited value of alarm features in the diagnosis of upper gastrointestinal malignancy: systematic review and meta-analysis显示文摘 | Vakil N Moayyedi P Fennerty MB | 2006 | Gastroenterology2006，131，2： | 1 |
| 12 | Eradication of helieobaeter pylori for non-ulcer dyspepsia 显示文摘 | MOAYYEDI P SOO S DEEKS J | 2005 | Coehrane Database Syst Rev2005，19，02： | 1 |
| 13 | American gastroenterological association technical review on the evaluation of dyspepsia显示文摘 | Talley NJ Vakil NB Moayyedi P | 2005 | Gastroenterology2005，129，5： | 1 |
| 14 | The eficacy of proton pump inhibitors in nonulcer dyspepsia:a systematic review an deconomic analysis显示文摘 | MOAYYEDI P DELANEY B C VAKIL N | 2004 | Gastroenterology2004，127，： | 1 |
| 15 | 1 The Leeds Dyspepsia questionnaire: a valid tool formeasuring the presence and severity of dyspepsia显示文摘 | Moayyedi P Duffett S Braunholtz S et a | 1998 | AlimentPharmacolTher1998，12，： | 1 |
| 16 | Asia-Pacific consensus guidelines on gastric cancer prevention显示文摘 | Foek K M Talley N Moayyedi P | 2012 | Journal of Gastroenterology and Hepatology2012，，03： | 1 |
| 17 | The efficacy of probi- otics in the treatment of irritable bowel syndrome: a systematic review显示文摘 | Moayyedi P Ford AC Talley NJ | 2010 | Gut2010，59，3： | 1 |
| 18 | The efficacy of probiotics in the treatment of irritable bowel syndrome: a systematic review显示文摘 | Moayyedi P Ford A C Talley N J | 2010 | Gut2010，59，3： | 1 |
| 19 | The influence of dyspepsia,Helicobacter pylori status and irritable bowel syndrome on quality of life in the community显示文摘 | Moayyedi P Braunholtz D Atha P | 1998 | Gut1998，42，： | 1 |
| 20 | Fecal microbiota transplantation induces remission in patients with active ulcerative colitis in a randomized, controlled trial显示文摘 | Moayyedi P SureUe M G Kim P T | 2015 | Gastroenterology2015，，00： | 1 |
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