|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Metal exposure and Alzheimer's pathogenesis.显示文摘 | Liu G Huang W Moir RD Vanderburg CR Lai B Peng Z Tanzi RE Rogers JT Huang X | 2006 | 中国生物学文摘2006，20，9： | 8 |
| 2 | The purification of ammonia monooxygenase from Paracoccus denitrficans显示文摘 | James W.B. Moir Lisa C. Crossman Stephen Spiro David J. Richardson | 1996 | FEBS Letters1996，，1： | 2 |
| 3 | Role of anti-stromal polypharmacy in increasing survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma显示文摘AIM: To investigate the survival impact of common pharmaceuticals, which target stromal interactions, following a pancreaticoduodenectomy for pancreatic ductal adenocarcinoma. METHODS: Data was collected retrospectively for 164 patients who underwent a pancreaticoduodenectomy for pancreatic ductal adenocarcinoma(PDAC). Survival analysis was performed on patients receiving the following medications: angiotensin-converting enzyme inhibitors(ACEI)/angiotensin Ⅱ receptor blockers(ARB), calcium channel blockers(CCB), aspirin, and statins. Statistical analysis included Kaplan-meier survival estimates and cox multivariate regression; the latter of which allowed for any differences in a range of prognostic indicators between groups. Medications showing a significant survival benefit were investigated in combination with other medications to evaluate synergistic effects.RESULTS: No survival benefit was observed with respect to ACEI/ARB(n = 41), aspirin or statins on individual drug analysis(n = 39). However, the entire CCB group(n = 26) showed a significant survival benefit on multivariate cox regression; hazard ratio(HR) of 0.475(CI = 0.250-0.902, P = 0.023). Further analysis revealed that this was influenced by a group of patients who were taking aspirin in combination with CCB; median survival was significantly higher in the CCB + aspirin group(n = 15) compared with the group taking neither drug(n = 98); 1414 d vs 601 d(P = 0.029, logrank test). Multivariate cox regression revealed neither aspirin nor CCB had a statistically significant impact on survival when given alone, however in combination the survival benefit was significant; HR = 0.332(CI = 0.126-0.870, P = 0.025). None of the other medications showed a survival benefit in any combination.CONCLUSION: Aspirin + CCB in combination appears to increase survival in patients with PDAC, highlighting the potential clinical use of combination therapy to target stromal interactions in pancreatic cancer. | Samuel J Tingle John A Moir Steven A White | 2015 | World Journal of Gastrointestinal Pathophysiology2015，6，4： | 2 |
| 4 | Degrees of reaction of the slag in some blends with Portland cements显示文摘 | Lumley J S Gollop R S Moir G K | 1996 | Cement and Concrete Research1996，26，1： | 2 |
| 5 | Laparoscopic esophagomyotomy for achalasia in children:Areview显示文摘Esophageal achalasia in children is rare but ultimately requires endoscopic or surgical treatment. Historically, Heller esophagomyotomy has been recommended as the treatment of choice. The refinement of minimally invasive techniques has shifted the trend of treatment toward laparoscopic Heller myotomy(LHM) in adults and children with achalasia. A review of the available literature on LHM performed in patients < 18 years of age was conducted. The pediatric LHM experience is limited to one multiinstitutional and several single-institutional retrospective studies. Available data suggest that LHM is safe and effective. There is a paucity of evidence on the need for and superiority of concurrent antireflux procedures. In addition, a more complete portrayal of complications and long-term(> 5 years) outcomes is needed. Due to the infrequency of achalasia in children, these characteristics are unlikely to be defined without collaboration between multiple pediatric surgery centers. The introduction of peroral endoscopic myotomy and single-incision techniques, continue the trend of innovative approaches that may eventually become the standard of care. | T Kumar Pandian Nimesh D Naik Aodhnait S Fahy Arman Arghami David R Farley Michael B Ishitani Christopher R Moir | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，2： | 2 |
| 6 | Genomic-Sequence Comparison of Two Unrelated Isolates of the Human Gastric Pathogen Helicobacterpylori 显示文摘 | Alm R A Ling L L Moir D T | 1999 | Nature1999，397，14： | 1 |
| 7 | Heterologous protein secre- tion from yeast显示文摘 | Smith R A Duncan M J Moir D T | 1985 | Science1985，20，： | 1 |
| 8 | Changes in activity of the Cu-Zn superoxide dismutase enzyme in tissues of the rat with changes in dietary copper显示文摘 | Paynter DI Moir R J Underwood EJ | 1979 | J Nutr1979，109，： | 1 |
| 9 | Conjugated linoleic acids (CLAs) regulate the expression of key apoptotic genes in human breast caner ceUs显示文摘 | MAJUMDER B WAHLE K W J MOIR S | 2002 | FASEB2002，16，： | 1 |
| 10 | The purification of ammonia monooxygenase from Paracoccus denitrificans显示文摘 | Moir J W Crossman L C Spiro S | 1996 | FEBS Lett1996，387，： | 1 |
| 11 | Degrees of reaction of the slag in some blends with Portland cements 显示文摘 | LUMLEY J S GALLOP R S MOIR G K | 1996 | Cem Concr Res1996，26，1： | 1 |
| 12 | Heterogeneity and the Voluntary Provision of Public Goods显示文摘 | Kenneth S. Chan Stuart Mestelman Robert Moir R. Andrew Muller | 1999 | Experimental Economics1999，，1： | 1 |
| 13 | Pathogenic mechanisms of HIV disease显示文摘 | Moir S Chun TW Fauci AS | 2011 | Annu Rev Pathol2011，6，： | 1 |
| 14 | Hydraulic and sedimentary characteristics of habitat utilized by Atlantic salmon for spawning in the Girnock Burn,Scotland显示文摘 | MOIR H J SOULSBY C YOUNGSON A | 1998 | Fisheries Management and Ecology1998，5，3： | 1 |
| 15 | Relationships between urbanization levels and the indus- trial structure of the labor force显示文摘 | Moir H | 1976 | Economic Development and Cultural Change1976，，： | 1 |
| 16 | Management of utility systems in the experimental aircraft programme显示文摘 | Seabrdge A G | 1986 | Aerospace1986，13，7： | 1 |
| 17 | Plasma progesterone concentrations in pregnant and non-pregnant llamas显示文摘 | Moir C E Shiach P | 1989 | Vet Res1989，125，： | 1 |
| 18 | The biceps femoris musculocutaneous flap in the repair of pressure sores around the hip显示文摘 | James JH Moir IH | | 0，，05： | 1 |
| 19 | B cells in HIV infection and disease 显示文摘 | Moir S Fauei AS | 2009 | Nat Rev Immunol2009，9，4： | 1 |
| 20 | Clearance of Alzheimer's Abeta peptide : the many roads to perdition 显示文摘 | TANZI R E MOIR R D WAGNER S L | 2004 | Neuron2004，43，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员