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| 1 | Mouse models in male fertility research显示文摘男不孕的基因原因的有限知识导致了很少处理并且指向了治疗学的选择。尽管识别引起变化的不孕的理想的途径是在人的人口进行研究,这条途径由于此处描述的限制慢慢地进行了。给男富饶的复杂性,全部过程不能在 vitro 被建模。因此,动物当模特儿,特别地老鼠模型,为基因鉴定和试验提供一种珍贵选择。自从在动物模型生产的分子的生物学和最近的进展的介绍,在与许多疾病联系的基因的鉴定和描述有实质的加速,包括不孕。老鼠模型的三种主要类型通常在生物医学的研究被使用,包括 knockout/knockin/gene-trapped,转基因、导致化学药品的点异种老鼠。使用这些老鼠模型,在为男富饶的 400 基因必需品上被揭示了。然而,几千基因涉及男富饶的复杂过程的规定,这被估计了,当许多如此的基因尚待被描绘。当前的评论绝非是这些鼠标模型,的一张全面的表相当,它包含鼠标模型怎么推进了我们出生后的细菌房间开发和男富饶规定的知识的例子。 | Duangporn Jamsai Moira K O'Bryan | 2011 | Asian Journal of Andrology2011，13，1： | 10 |
| 2 | The role of cysteine-rich secretory proteins in male fertility显示文摘充满半胱氨酸的能分泌的蛋白质(CRISPs ) 是 CRISP,的亚群抗原 5 并且 Pr-1 (帽子) 蛋白质总科,并且仅仅在脊椎动物被发现。他们显示出强壮的表示偏爱到哺乳动物的男繁殖的道和有毒的爬行动物的毒液。在男繁殖的道以内, CRISPs 在跨越 haploid 细菌房间开发, epididymal 成熟, capacitation,活动性和授精的实际进程的男细菌房间生物学的许多方面被含有。在结构的水平, CRISPs 由二个领域,一个帽子领域,它在房间鈥揷e ll 粘附被含有,和一个松脆的领域组成,它被显示了越过多重种类调整离子隧道的几个班。此处,我们将在男富饶在 CRISPs 的角色上考察当前的文学,并且由到相关非哺乳动物的蛋白质的推理,推断潜在的生物化学的功能。 | Adam J Koppers Thulasimala Reddy Moira K O'Bryan | 2011 | Asian Journal of Andrology2011，13，1： | 8 |
| 3 | General Practitioners'experiences of bereavement care and their educationalsupport needs:a qualitative study显示文摘 | Moira O ’ Connor Lauren J Breen | 2014 | BMC Med Educ2014，14，1： | 1 |
| 4 | Nowhere to hide: Awareness and perceptions of environmental change, and their influence on relationships with place显示文摘 | Ruth Rogan Moira O’Connor Pierre Horwitz | 2005 | Journal of Environmental Psychology2005，，2： | 1 |
| 5 | Regulation of Germ Cell and Sertoli Cell Development by Activin, Follistatin, and FSH显示文摘 | Terri Meehan Stefan Schlatt Moira K. O’Bryan David M. de Kretser Kate Lakoski Loveland | 2000 | Developmental Biology2000，，2： | 1 |
| 6 | Cellular Signaling by Fibroblast Growth Factors (FGFs) and Their Receptors (FGFRs) in Male Reproduction显示文摘 | Leanne M. Cotton Moira K. O?Bryan Barry T. Hinton | 2008 | Endocrine Reviews2008，，2： | 1 |
| 7 | Biodiversity, endemism, sense of place,and public health: inter-relationships for Australian Inland Aquatic Systems显示文摘 | Pierre Horwitz Michael Lindsay Moira O'Connor | 2001 | Ecosystem Health2001，7，4： | 1 |
| 8 | Indueible nitric oxide synthase in the rat testis :evidence for potential roles in both normal function and inflammation-mediated infertility显示文摘 | Moira K O'Bryan Schlatt Stefan | 2000 | Biol F Reprod2000，63，： | 1 |
| 9 | Long-term outcomes of pediatric liver transplantation in acute liver failure vs end-stage chronic liver disease:A retrospective observational study显示文摘BACKGROUND Children with acute liver failure(ALF)who meet the criteria are eligible for super-urgent transplantation,whereas children with end-stage chronic liver disease(ESCLD)are usually transplanted electively.Pediatric liver transplantation(PLT)in ALF and ESCLD settings has been well described in the literature,but there are no studies comparing the outcomes in these two groups.AIM To determine if there is a difference in post-operative complications and survival outcomes between ALF and ESCLD in PLT.METHODS This was a retrospective observational study of all primary PLTs performed at a single center between 2000 and 2019.ALF and ESCLD groups were compared for pretransplant recipient,donor and operative parameters,and post-operative outcomes including graft and patient survival.RESULTS Over a 20-year study period,232 primary PLTs were performed at our center;195 were transplanted for ESCLD and 37 were transplanted for ALF.The ALF recipients were significantly older(median 8 years vs 5.4 years;P=0.031)and heavier(31 kg vs 21 kg;P=0.011).Living donor grafts were used more in the ESCLD group(34 vs 0;P=0.006).There was no difference between the two groups concerning vascular complications and rejection,but there were more bile leaks in the ESCLD group.Post-transplant patient survival was significantly higher in the ESCLD group:1-,5-,and 10-year survival rates were 97.9%,93.9%,and 89.4%,respectively,compared to 78.3%,78.3%,and 78.3%in the ALF group(P=0.007).However,there was no difference in 1-,5-,and 10-year graft survival between the ESCLD and ALF groups(90.7%,82.9%,77.3%vs 75.6%,72.4%,and 66.9%;P=0.119).CONCLUSION Patient survival is inferior in ALF compared to ESCLD recipients;the main reason is death in the 1st year post-PLT in ALF group.Once the ALF children overcome the 1st year after transplant,their survival stabilizes,and they have good long-term outcomes. | Amr M Alnagar Abdul R Hakeem Khaled Daradka Eirini Kyrana Marumbo Methga KarthikeyanPalaniswamy Sanjay Rajwal Jamila Mulla Moira O'meara Vivek Upasani Dhakshinamoorthy Vijayanand Raj Prasad Magdy S Attia | 2023 | World Journal of Transplantation2023，13，3： | 1 |
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