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| 1 | 'Unknown Genome' proteomics: A new NAD (P)-dependent epimerase/dehydratase re- vealed by N-terminal sequencing, inverted PCR, and high resolution mass spectrometry显示文摘 | SIMEONOVA D D SUSNEA L S MOISE A | 2009 | Mo- lecular ~ Cellular Proteomics2009，8，1： | 1 |
| 2 | Determinants of the Middle Cerebral Artery Peak Systolic Velocity in the Human Fetus显示文摘 | Picklesimer AH Oepkes D Moise KJ | 2007 | Am J Obstetrics Gynecol2007，197，5： | 1 |
| 3 | Ex - utero intrapartum treatment procedure for giant neck masses - fetal and maternal outcomes 显示文摘 | Lazar D A Olutoye 0 0 Moise K J | 2011 | J Ped- iatr Surg2011，46，5： | 1 |
| 4 | Anxi- ety sensitivity and medication nonadherence in patients with uncontrolled hypertension 显示文摘 | ALCANTARA C EDMONDSON D MOISE N | 2014 | J Psychiosom Res2014，77，4： | 1 |
| 5 | Discoid lupus erythematosus in children : Clinical, histopathologic, and follow - up features in 27 cases 显示文摘 | Moises - Alfaro C Berron - Perez R Carrasco - Daza D | 2003 | Pediatr Dermatol2003，20，2： | 1 |
| 6 | Probabilistic predictions of climate change for Australia and southern Africa using the reliability ensemble average of IPCC CMIP3 model simulations显示文摘 | Moise A F Hudson D A | 2008 | Journal of Geophysical Research: Atmospheres(1984-2012)2008，，： | 1 |
| 7 | Determinants of the middle cerebral artery peak systolic vclocity in the human fetus显示文摘 | Picklesimer AH Ocpkcs D Moise KJ Jr | 2007 | Am J Obstet Gynecol2007，197，5： | 1 |
| 8 | MRI and Clinical Decision in Cochlear Implanttion显示文摘 | Moises A Carrier D | 1996 | Am J Otol1996，17，4： | 1 |
| 9 | Caesarean section using total intravenous anaesthesia in a patient with Ebstein's anomaly complicated by supraventricular tachycardia显示文摘 | Macfarlane AJ Moise S Smith D | 2007 | Int J Obstet Anesth2007，16，2： | 1 |
| 10 | Optically switched resonant tunneling diodes显示文摘 | MOISE T S KAO Y C GARRETT L D | 1995 | Appl phys Lett1995，66，9： | 1 |
| 11 | Anxiety sensitivity and medication nonadherence in patients with uncontrolled hyperten- sion显示文摘 | Alcantara C Edmondson D Moise N | 2014 | J Psychosom Res2014，77，4： | 1 |
| 12 | Optically switch resonant tunneling diodes显示文摘 | Moise T S Kao Y C Garrett L D | 1995 | Appl Phys Lett1995，66，9： | 1 |
| 13 | Transition metal promoted synthesis of N, N-dimethyl tertiary amides from 1,3-dienes 显示文摘 | SZYMONIAK J FELIX D MOISE C | 1996 | Tetrahedron Letters1996，37，1： | 1 |
| 14 | Microbiological effects of prior vancomycin use in patients with methicillin-resistant Staphylococcus aureus bacteraemia 显示文摘 | Moise D | 2008 | J Antimicrob Chemother2008，61，： | 1 |
| 15 | Heterotopic abdominal pregnancy treated at laparoscopy显示文摘 | PISARSKA M D CASSON P R MOISE K J | 1998 | Fertility Sterility1998，70，： | 1 |
| 16 | Caesarean section u- sing total intravenous anaesthesia in a patient with Ebstein's anom- aly complicated by supraventricular tachyeardia 显示文摘 | MAEFARLANE A J MOISE S SMITH D | 2007 | Obstet Anesth2007，16，2： | 1 |
| 17 | Risperidone - induced hyperprolactinemia in adolescents : a case series显示文摘 | Madhusoodanan S Moise D | 2006 | Journal of Clinical Psychiatry2006，67，7： | 1 |
| 18 | Daclatasvir vs telaprevir plus peginterferon alfa/ribavirin for hepatitis C virus genotype 1显示文摘AIM: To evaluate daclatasvir vs telaprevir, each combined with peginterferon alfa-2a/ribavirin(peg IFN/RBV), in treatment-naive hepatitis C virus(HCV) genotype(GT) 1-infected patients.METHODS: In this phase 3, randomized, open-label, noninferiority study, 602 patients were randomly assigned(2:1) to daclatasvir vs telaprevir, stratified by IL28 B rs12979860 host genotype(CC vs non-CC), cirrhosis status(compensated cirrhosis vs no cirrhosis), and HCV GT1 subtype(GT1a vs GT1b). Patients were selected by study inclusion criteria from a total of 793 enrolled patients. Patients received daclatasvir 60 mg once daily or telaprevir 750 mg 3 times daily plus peg IFN/RBV. Daclatasvir recipients received 24 wk of daclatasvir plus peg IFN/RBV; those without an extended rapid virologic response(e RVR; undetectable HCV-RNA at weeks 4 and 12) received an additional 24 wk of peg IFN/RBV. Telaprevir-treated patients received 12 wk of telaprevir plus peg IFN/RBV followed by 12(with e RVR) or 36(no e RVR) wk of peg IFN/RBV. The primary objective was to compare for noninferiority of sustained virologic response rates at posttreatment week 12(SVR12) in GT1b-infected patients. Key secondary objectives were to demonstrate that the rates of anemia(hemoglobin < 10 g/d L) and rashrelated events, through week 12, were lower with daclatasvir + peg IFN/RBV than with telaprevir + peg IFN/RBV among GT1b-infected patients. Resistance testing was performed using population-based sequencing of the NS5 A region for all patients at baseline, and for patients with virologic failure or relapse and HCV-RNA ≥ 1000 IU/m L, to investigate any link between NS5 A polymorphisms associated with daclatasvir resistance and virologic outcome. RESULTS: Patient demographics and disease characteristics were generally balanced across treatment arms; however, there was a higher proportion of black/African Americans in the daclatasvir groups(6.0% and 8.2% in the GT1 b and GT1 a groups, respectively) than in the telaprevir groups(2.2% and 3.0%). Among GT1 binfected patients, daclatasvir plus peg IFN/RBV was noninferior to telaprevir plus peg IFN/RBV for SVR12 [85%(228/268) vs 81%(109/134); difference, 4.3%(95%CI:-3.3% to 11.9%)]. Anemia(hemoglobin < 10 g/d L) was significantly less frequent with daclatasvir than with telaprevir [difference,-29.1%(95%CI:-38.8% to-19.4%)]. Rash-related events were also less common with daclatasvir than with telaprevir, but the difference was not statistically significant. In GT1 ainfected patients, SVR12 was 64.9% with daclatasvir and 69.7% with telaprevir. Among both daclatasvir and telaprevir treatment groups, across GT1b- or GT1a-infected patients, lower response rates were observed in patients with IL28 B non-CC and cirrhosis- factors known to affect response to peg IFN/RBV. Consistent with these observations, a multivariate logistic regression analysis in GT1b-infected patients d e m o n s t ra t e d t h a t S V R 1 2 wa s a s s o c i a t e d w i t h IL28 B host genotype(CC vs non-CC, P = 0.011) and cirrhosis status(absent vs present, P = 0.031). NS5 A polymorphisms associated with daclatasvir resistance(at L28, R30, L31, or Y93) were observed in 17.3% of GT1b-infected patients at baseline; such variants did not appear to be absolute predictors of failure since 72.1% of these patients achieved SVR12 compared with 86.9% without these polymorphisms. Among GT1b-infected patients, treatment was completed by 85.4%(229/268) in the daclatasvir group, and by 85.1%(114/134) in the telaprevir group, and among GT1a-infected patients, by 67.2%(90/134) and 69.7%(46/66), respectively. Discontinuations(of all 3 agents) due to an AE were more frequent with telaprevir than with daclatasvir, whereas discontinuations due to lack of efficacy were more frequent with daclatasvir, due, in part, to differences in futility criteria. CONCLUSION: Daclatasvir plus peg IFN/RBV demonstrated noninferiority to telaprevir plus peg IFN/RBV for SVR12 and was well-tolerated in treatment-naive GT1 binfected patients, supporting the use of daclatasvir with other direct-acting antivirals. | Ira Jacobson Stefan Zeuzem Robert Flisiak Brygida Knysz Stefan Lueth Dorota Zarebska-Michaluk Ewa Janczewska Peter Ferenci Moises Diago Anna Linda Zignego Rifaat Safadi Yaacov Baruch Dzhamal Abdurakhmanov Stephen Shafran Dominique Thabut Rafael Bruck Adrian Gadano Alexander James Thompson Justin Kopit Fiona Mc Phee Tracy Michener Eric A Hughes Philip D Yin Stephanie Noviello | 2016 | World Journal of Gastroenterology2016，22，12： | 1 |
| 19 | A wavelet-based differential transformer protection显示文摘 | MOISES G NICOLETTI D | 1999 | IEEE Transactions on Power Delivery1999，14，4： | 1 |
| 20 | Caesarean section using total intravenous anaesthesia in a patient with Ebstein's a- nomaly complicated by supraventricular tachycardia 显示文摘 | Macfarlane AJ Moise S Smith D | 2007 | Int J Obstet Anesth2007，16，2： | 1 |
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