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| 1 | Using old liver grafts for liver transplantation: Where are the limits?显示文摘The scarcity of ideal liver grafts for orthotopic liver transplantation(OLT) has led transplant teams to investigate other sources of grafts in order to augment the donor liver pool. One way to get more liver grafts is to use marginal donors, a not well-defined group which includes mainly donors > 60 years, donors with hypernatremia or macrosteatosis > 30%, donors with hepatitis C virus or hepatitis B virus positive serologies, cold ischemia time > 12 h, non-heart-beating donors, and grafts from split-livers or living-related donations. Perhaps the most practical and frequent measure to increase the liver pool, and thus to reduce waiting list mortality, is to use older livers. In the past years the results of OLT with old livers have improved, mainly due to better selection and maintenance of donors, improvements in surgical techniques in donors and recipients, and intra- and post-OLT management. At the present time, sexagenarian livers are generally accepted, but there still exists some controversy regarding the use of septuagenarian and octogenarian liver grafts. The aim of this paper is to briefly review the aging process of the liver and reported experiences using old livers for OLT. Fundamentally, the series of septuagenarian and octogenarian livers will be addressed to see if there is a limit to using these aged grafts. | Carlos Jiménez-Romero Oscar Caso Maestro Félix Cambra Molero Iago Justo Alonso Cristina Alegre Torrado Alejandro Manrique Municio Jorge Calvo Pulido Carmelo Loinaz Segurola Enrique Moreno González | 2014 | World Journal of Gastroenterology2014，20，31： | 11 |
| 2 | Aldosterone impairs insulin responsiveness in U-937 hunmn promonocytic cells via the downregulation of its own receptor显示文摘 | Campion J Maestro B Molero S | 2002 | Cell Biochem Funct2002，20，3： | 1 |
| 3 | Aldosterone impairs insulin responsiveness in U-937 human promonocytic cells via the downregulation of its own receptor显示文摘 | Campion J Maestro B Molero S | 2002 | Cell Biochem Funct2002，20，3： | 1 |
| 4 | Quality of borage seed oil extracted by liquid and supercritical carbon dioxide 显示文摘 | Molero G A Martiynez de la O E | 2002 | Chemical Engineering Journal2002，88，123： | 1 |
| 5 | Aldosterone impars insulin responsiveness in U-937 human promonocytie cells via the downregulation of its own receptor显示文摘 | Campion J Maestro B Molero S | 2002 | Cell Biochem Funct2002，20，3： | 1 |
| 6 | Effects of a specific blend of essential oil compounds on dry matter and crude protein degradability in heifers fed diets with different forage to concentrate ratios显示文摘 | MOLERO R IBARS M CALSAMIGLIA S | 2004 | Animal Feed Science and Technology2004，114，1234： | 1 |
| 7 | Measurement of The Degraded Depth iu Cementitious Materials by Automatic Digital image Processing 显示文摘 | Segura I Molero M Aparicio S | 2010 | Measurement science and technology2010，，21： | 1 |
| 8 | Evaluation of a Municipal Landfill Site in Southern Spain with GIS-aided Methodology 显示文摘 | Zamorano M Molero E Hurtado A | 2008 | J Hazard Mater2008，160，23： | 1 |
| 9 | Recovery of polyols from flexible polyurethane foam by'split-phase' glycolysis: Study on the influence of reaction parameters显示文摘 | Carolina Molero Antonio de Lucas Juan F Rodr guez | 2008 | Polymer Degradation and Stability2008，93，： | 1 |
| 10 | Solubility of the antibiotic penicillin G in supercritical carbon dioxide 显示文摘 | M D Gordillo MA Blanco A Molero | 1999 | Journal of Supercritical Fluids1999，，15： | 1 |
| 11 | The combined effect of constant water deficit and nitrogen supply on WUE, NUE and AI3C in durum wheat potted plants显示文摘 | Cabrera-Bosquet L Molero G Bort J 1Nogues S Araus J L | 2007 | Ann Appl Biol2007，151，： | 1 |
| 12 | Transcriptional activation of the, hu- man insulin receptor gene by 1,25-dihydioxyvitam in (3)显示文摘 | Maestro B Molero S Bajo S | 2002 | Cell Bio- ehem Func12002，20，3： | 1 |
| 13 | Effect of removal of adventitia on vascular smooth muscle contraction and relaxation显示文摘 | Gonzalez M C Arribas S M Molero F Fernandez-Alfonso M S | 2001 | Am J Physiol Heart Circ Physiol2001，280，： | 1 |
| 14 | Performance evaluation and simulation of a new absorbent for an absorption refrigeration system显示文摘 | Lucas A D Donate M Molero C | | 0，，： | 1 |
| 15 | ETB receptor-deficient rats exhibit reduced contraction to ET-1 despite an increase in ETA receptors显示文摘 | Perry MG Molero MM Giulumian AD | 2001 | Am J Physiol Heart Circ Physiol2001，281，6： | 1 |
| 16 | Release of insulin receptor substrate proteins from an intracellular complex coincides with the development of insulin resistance显示文摘 | Clark SF Molero JC James D E | 2000 | J Biol Chem2000，275，： | 1 |
| 17 | Analysis and optimizations of global and local versions of the RX algorithms for anomaly detection in hyperspectral data显示文摘 | Molero J M Garzon E M Garcia I | 2013 | IEEE Jounal of Selected Topics in Applied Earth Observations and Remote Sensing2013，6，2： | 1 |
| 18 | Effect of removal of adventitia on vascular smooth muscle contraction and relaxation显示文摘 | Gonzalez MC Arribas SM Molero F | 2001 | Am J Physiol2001，280，6： | 1 |
| 19 | Endothelin-1 induced proinflammatory markers in the myocardium and leukocytes of guinea pigs:role of glycoprotein Ⅱb / ⅢA receptors显示文摘 | Molero L Farre J Garcia Mendez A | 2003 | Cardiovasc Res2003，57，1： | 1 |
| 20 | Patellofemoral crepitation and clunk following modem, fixed - bearing total knee ar- throplasty 显示文摘 | Peralta - Molero JV Gladnick BP Lee YY | 2014 | J Arthroplasty2014，3，： | 1 |
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