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| 1 | Heat shock protein 90 inhibition by 17-DMAG lessens disease in the MRL/Ipr mouse model of systemic lupus erythematosus显示文摘热吃惊蛋白质 90 的提高的表示(HSP90 ) 在全身的豺狼座 erythematosus (SLE ) 的肾和浆液被发现了病人和 MRL/Mp-Fas lpr /Fas lpr (MRL/lpr ) 自体免疫的老鼠。如果 HSP90 的抑制将在 MRL/lpr 老鼠减少疾病,我们调查了。在在 vivo 的 vitro,有在 IL-6 的有免疫力刺激的显示出的减少的表示以前的 HSP90 禁止者 Geldanamycin 的 mesangial 房间的预告的处理, IL-12 和号码,我们发现当与 C57BL/6 相比鼠标和 MRL/lpr 鼠标与 HSP90 禁止者 17-DMAG 对待时, HSP90 表示在 MRL/lpr 肾被提高。与 17-DMAG 对待的 MRL/lpr 老鼠显示出减少的 proteinuria 并且减少了浆液 anti-dsDNA 抗体生产。Glomerulonephritis 和 glomerular IgG 和 C3 没被 17-DMAG 的管理显著地在 MRL/lpr 影响。17-DMAG 增加了 CD8 + T 房间,减少的双 negative T 房间,减少 CD4/CD8 比率和减少的小囊的 B 房间。这些研究建议 HSP90 可以在调整 T 房间区别和激活起一个作用并且 HSP90 抑制可以在豺狼座减少发炎。 | Samuel K Shimp III Cristen B Chafin Nicole L Regna Sarah E Hammond Molly A Read David L Caudell Marissa Nichole Rylander Christopher M Reilly | 2012 | Cellular & Molecular Immunology2012，9，3： | 3 |
| 2 | Giant Aneurysms of Coronary Arteries and Saphenous Vein Grafts: Angiographic Findings and Histopathological Correlates显示文摘 | Topaz O Molly S R Shannon M B etal | 2005 | Cardiovascular Pathology2005，14，6： | 1 |
| 3 | Adapting parentchild interaction therapy for young children with separation anxiety disorder显示文摘 | Donna B Pincus Sheila M Eyberg Molly L Choate | 2005 | Education and Treatment of Children2005，28，2： | 1 |
| 4 | Prediction of long term chloride concentra- tion in concrete显示文摘 | MANGAT P MOLLY B | 1994 | Materials and Structures1994，，27： | 1 |
| 5 | MicroRNA promoter element discovery in Arabidopsis显示文摘 | Molly M Vesselin B Ventsislav R | 2006 | RNA2006，12，： | 1 |
| 6 | Platelet adhesion involves a novel interaction between vimentin and yon Willebrand factor under high shear stress 显示文摘 | Qi D Molly B Correa JI | 2014 | Blood2014，123，17： | 1 |
| 7 | Synthesis and characterization of novel polysiloxane-grafted fluoropolymers显示文摘 | Bilal B Patricia H M L Molly S S | 2005 | Canadian Journal of Chemistry-Revue Canadienne De Chimie2005，83，67： | 1 |
| 8 | Prediction of long term chloride concentration in concrete显示文摘 | MANGAT P S MOLLY B T | 1994 | Materials and Structures1994，27，6： | 1 |
| 9 | High-temperature texture in naturally deformed Carrara marble from the Alpi Apuane, Italy 显示文摘 | Leiss B Molli G | 2003 | Journal of Structural Geology2003，25，4： | 1 |
| 10 | Assessment of cyclic changes of microvessels in ovine ovaries using Sonovue contrast-enhanced ultrasound显示文摘 | Henri M Molly B Bruno G | 2006 | Ultrasound in Med& Biol2006，32，2： | 1 |
| 11 | Reporting appraising, and integrating data on genotype prevalence and gene-disease associations 显示文摘 | Julian L Linda B Molly SB | 2002 | Am J Epidemol2002，156，5： | 1 |
| 12 | The south Tibetan detachment system in the Rongbuk valley, Everest region: De formation features and geological implications显示文摘 | Carosi R Lombardo B Molli G | 1998 | Journal of Asian Earth Sciences1998，16，： | 1 |
| 13 | Contaminant Vapor Adsorption at the Gas-water Interface in Soils显示文摘 | MOLLY S C MARK L B | 2000 | Environ Sci Tech2000，34，1： | 1 |
| 14 | Improved protein solubility in two-dimensional eletrophoresis using tributyl phosphine as reduxing agent显示文摘 | HERBERT B R MOLLY M P WALSH B J | 1998 | Electrophoresis1998，19，： | 1 |
| 15 | Utilization of reclaimed waste-water for irrigation of field-grown melons by surface and subsurface drip irrigation显示文摘 | Mollie S Nirit B | 2011 | Israel Journal of Plant Sciences2011，59，： | 1 |
| 16 | Contaminant vapor adsorption at the gas water interface in soils显示文摘 | Molly S C Mark L B | 2000 | Environ Sci Tech2000，34，1： | 1 |
| 17 | Effect of intravenous midazolam on the work of breathing显示文摘 | Montravers P Dureuil B Mollies S | 1994 | Anesth Analg1994，97，9： | 1 |
| 18 | PAK signaling in oncogenesis 显示文摘 | MOLLI P R LID Q MURRAY B W | 2009 | Oncogene2009，28，28： | 1 |
| 19 | Prediction of long term chloride concentration in concrete显示文摘 | MANGAT P MOLLY B | 1994 | Materials and Structures1994，，27： | 1 |
| 20 | Prediction of long term chloride concentration in concrete显示文摘 | Mangat P S Molly B T | 1994 | Materials and Structure1994，27，： | 1 |
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