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| 1 | Introducing an enhanced recovery after surgery program in colorectal surgery:A single center experience显示文摘AIM:To study the implementation of an enhanced recovery after surgery(ERAS)program at a large University Hospital from'pilot study'to'standard of care'.METHODS:The study was designed as a prospective single centre cohort study.A prospective evaluation of compliance to a protocol based on full application of all ERAS principles,through the progressive steps of its implementation,was performed.Results achieved in the initial pilot study conducted by a dedicated team(n=47)were compared to those achieved in the shared protocol phase(n=143)three years later.Outcomes were length of postoperative hospital stay,readmission rate,compliance to the protocol and morbidity.Primary endpoint was the description of the results and the identification of critical issues of large scale implementation of an ERAS program in colorectal surgery emerged in the experience of a single center.Secondary endpoint was the identification of interventions that have been proven to be effective for facilitating the transition from traditional care pathways to a multimodal management protocol according to ERAS principles in colorectal surgery at a single center.RESULTS:During the initial pilot study(March 2009 to December 2010;47 patients)conducted by a dedicated multidisciplinary team,compliance to the items of ERAS protocol was 93%,with a median length of hospital stay(LOS)of 3 d.Early anastomotic fistulas were observed in 2 cases(4.2%),which required reoperation(Clavien-Dindo gradeⅢb).None of the patients had been discharged before the onset of the complication,which could therefore receive prompt treatment.There were also four(8.5%)minor complications(ClavienDindo gradeⅡ).Thirty days readmission rate was 4%.Perioperative mortality was nil.After implementation of the protocol throughout the Hospital in unselected patients(May 2012 to December 2012;147 patients)compliance was 74%,with a median LOS of 6 d.Early anastomotic fistulas were observed in 11 cases(7.7%),5(3.5%)of which required reoperation(Clavien-Dindo gradeⅢb).Two early anastomotic fistulas were treated by radiologic/endoscopic manoeuvres and 4 were treated conservatively.There were also 36(25.2%)minor complications,21(14.7%)of which were Clavien-Dindo gradeⅡand 15(10.5%)of which were Clavien-Dindo gradeⅠ.Only two patients whose course was adversely affected by the development of an anastomotic leak had been discharged before the onset of the complication itself,requiring readmission.Readmission rate within 30 d was 4%.Perioperative mortality was 1%.CONCLUSION:Our results confirm that introduction of an ERAS protocol for colorectal surgery allows quickerpostoperative recovery and shortens the length of stay compared to historical series. | Stefano Bona Mattia Molteni Riccardo Rosati Ugo Elmore Pietro Bagnoli Roberta Monzani Monica Caravaca Marco Montorsi | 2014 | World Journal of Gastroenterology2014，20，46： | 30 |
| 2 | History and evolution of the use of oral mucosa for urethral reconstruction显示文摘We report here the history and evolution of the use of oral mucosa in reconstructive urethral surgery since it was first used for urethroplasty in 1894.Since that time,many authors have contributed to develop,improve and popularize the use of oral mucosa as a substitute material.Paediatric urologists should be considered pioneers on the use of oral mucosa as they used it to repair primary and failed hypospadias.The use of oral mucosa to repair penile and bulbar urethral strictures was described,for the first time,in 1993.Important evolutions in the technique for harvesting oral mucosa from the cheek were reported in 1996.Today,oral mucosa is considered the gold standard material for any type of anterior urethroplasty in a one-or two-stage repair due to its biological and structural characteristics that make it a highly versatile that is adaptable to any environment required by the reconstructive urethral surgery.As the future approaches,tissue engineering techniques will provide patients with new materials originating from the oral epithelial mucosal cells,which are cultured and expanded into a scaffold.However,the path to reach this ambitious objective is still long and many difficulties must be overcome along the way. | Guido Barbagli Sofia Balo Francesco Montorsi Salvatore Sansalone Massimo Lazzeri | 2017 | Asian Journal of Urology2017，4，2： | 6 |
| 3 | Heavy cigarette smoking and alcohol consumption are associated with impaired sperm parameters in primary infertile men显示文摘We assessed the concomitant impact of cigarette smoking and alcohol con sumption in men presenting for primary couple's infertility.Data from 189 in fertile men were an a lyzed.Semen analysis,serum hormones,and sperm DNA fragmentation(SDF)were obtained.Smoking status was categorized as follows:current nonsmoker(-S),moderate smoker(+MS),and heavy smoker(+HS).Alcohol consumption was categorized as follows:abstainer(-D),moderate drinker(+MD),and heavy drinker(+HD).Descriptive statistics and logistic regression models were applied.Among all the participants,132(69.8%),30(15.9%),and 27(14.3%)patients were-S,+MS,and+HS,respectively.In addition,67(35.4%),77(40.7%)and 45(23.8%)men were-D,+MD and+HD,respectively.Regarding concomitant habits,52(27.5%)patients were nonsmokers and abstainers(-S/-D:Group 1),91(48.1%)had at least one recreational habit(-S/+D or+S/-D:Group 2),and 46(24.3%)were both smokers and drinkers(+S/+D:Group 3).Sperm concentration and progressive motility were lower in+HS and+HD,compared with-S and-D(all P<0.05),respectively.Similarly,both parameters were significantly lower in Group 3 than Groups 1 and 2(all P<0.05).SDF values were higher in Group 3 than Groups 1 and 2(both P<0.05).In multivariate analysis,follicle-stimulating hormone(FSH)levels and concomitant+S/+D status were independent predictors of impaired sperm concentration and progressive motility(all P<0.05).Heavy smoking and heavy drinking were associated with worse seminal parameters than moderate smoking/drinking and nonsmoking/abstaining.When concomitant,+S/+D status has an even greater detrimental effect on semen parameters. | Luca Boeri Paolo Capogrosso Eugenio Ventimiglia Filippo Pederzoli Walter Cazzaniga Francesco Chierigo Federico Deho Emanuele Montanari Francesco Montorsi Andrea Salonia | 2019 | Asian Journal of Andrology2019，21，5： | 6 |
| 4 | Risk of postoperative recurrence and postoperative management of Crohn's disease显示文摘Crohn's disease (CD) is a chronic inflammatory disease of the digestive tract with systemic manifestations. Etiology is unknown, even if immunological, genetic and environmental factors are involved. The majority of CD patients require surgery during their lifetime due to progressive bowel damage, but, even when all macroscopic lesions have been removed by surgery, the disease recurs in most cases. Postoperative management represents therefore a crucial mean for preventing recurrence. Several drugs and approaches have been proposed to achieve this aim. Endoscopic inspection of the ileocolic anastomosis within 1 year from surgery is widely encouraged, given that endoscopic recurrence is one of the greatest predictors for clinical recurrence. A strategy should be planned only after stratifying patients according to their individual risk of recurrence, avoiding unnecessary therapies when possible benefits are reduced, and selecting high-risk patients for more aggressive intervention. | Antonino Spinelli Matteo Sacchi Gionata Fiorino Silvio Danese Marco Montorsi | 2011 | World Journal of Gastroenterology2011，17，27： | 4 |
| 5 | Guidelines on Male Sexual Dysfunction: Erectile Dysfunction and Premature Ejaculation显示文摘 | Konstantinos Hatzimouratidis Edouard Amar Ian Eardley Francois Giuliano Dimitrios Hatzichristou Francesco Montorsi Yoram Vardi Eric Wespes | 2010 | European Urology2010，，5： | 3 |
| 6 | Laparoscopic Rectal Resection for Cancer: Effects of Conversion on Short-Term Outcome and Survival显示文摘 | Matteo Rottoli Stefano Bona Riccardo Rosati Ugo Elmore Paolo P. Bianchi Antonino Spinelli Cristina Bartolucci Marco Montorsi | 2009 | Annals of Surgical Oncology2009，，： | 2 |
| 7 | Laparoscopic liver resections for hepatocellular carcinoma. Is it a feasible option for patients with liver cirrhosis?显示文摘 | R. Santambrogio L. Aldrighetti M. Barabino C. Pulitanò M. Costa M. Montorsi G. Ferla E. Opocher | 2009 | Langenbeck’s Archives of Surgery2009，，2： | 2 |
| 8 | Nephron-sparing Surgery Is Equally Effective to Radical Nephrectomy for T1BN0M0 Renal Cell Carcinoma: A Population-based Assessment显示文摘 | Maxime Crépel Claudio Jeldres Paul Perrotte Umberto Capitanio Hendrik Isbarn Shahrokh F. Shariat Daniel Liberman Maxine Sun Giovanni Lughezzani Philippe Arjane Hugues Widmer Markus Graefen Francesco Montorsi Jean-Jacques Patard Pierre I. Karakiewicz | 2010 | Urology2010，，： | 2 |
| 9 | A Softinput Softoutput APP Module for Iterative Decoding of Concatenated Codes显示文摘 | BENEDETTO S DIVSALAR D MONTORSI O | 1997 | IEEE Communication Letters1997，1，： | 1 |
| 10 | The ageing male and erectile dys- functlon显示文摘 | Montorsi F Salonia A Deho F | 2002 | World J Urol2002，20，1： | 1 |
| 11 | Soft-input soft-output modules for the construction and distributed iterative decoding of code networks显示文摘 | IBENEDETI'O S DIVSALAR D MONTORSI G | 1998 | European Transactions on Telecommunications1998，9，： | 1 |
| 12 | Evidence based assessment of long-term results of plaque incision and vein grafting for Peyronie's disease显示文摘 | Montorsi F Salonia A Maga T | 2000 | J Urol2000，163，6： | 1 |
| 13 | Acute kidney injury in ST-segment elevation acute myocardial infarction complicated by cardiogenic shock at admission显示文摘 | Giancarlo Marenzi Emilio Assanelli Jeness Campodonico Monica De Metrio Gianfranco Lauri Ivana Marana Marco Moltrasio Mara Rubino Fabrizio Veglia Piero Montorsi Antonio L. Bartorelli | 2010 | Critical Care Medicine2010，，2： | 1 |
| 14 | Survival and recurrences after hepatic resection or radiofrequency for hepatocellular carcinoma in cirrhotic patients:a multivariate analysis显示文摘 | Montorsi M Santambrogio R Bianchi P | 2005 | J Gastrointest Surg2005，9，1： | 1 |
| 15 | Serial concatenation of interleaved codes: Performance analysis, design, and iterative decoding 显示文摘 | Divsalar D Montorsi G | 1998 | IEEE Trans On Information Theory1998，44，： | 1 |
| 16 | Stent thrombosis after sirolimus- and paclitaxel-eluting stent implantation in daily clinical practice: analysis of a single center registry 显示文摘 | Trabattoni D Fabbiocchi F Montorsi P | 2007 | Catheter Cardiovasc Interv2007，70，3： | 1 |
| 17 | Unveiling Turbo code: some results on parallel concatenated coding schemes显示文摘 | Benedetto S Montorsi G | 1996 | IEEE Trans Imform Theory1996，42，2： | 1 |
| 18 | Stent thrombosis after sirolimus - and paclitaxel - eluting stem implantationin daily clinical practice :analysis of a singlecenter registry显示文摘 | Trabattoni D Fabbiocchi F Montorsi P | 2007 | Catheter Cardivovasc Interv2007，70，3： | 1 |
| 19 | Unveiling turbo codes: some results on parallel concatenated coding schemes 显示文摘 | Benedetto S Montorsi G | 1996 | IEEE Trans Inform Theory1996，42，2： | 1 |
| 20 | Eight-year experience with transperitoneal laparoscopic adrenal surgery 显示文摘 | Guazzoni G Cestari A Montorsi F | 2001 | J Urol2001，166，3： | 1 |
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