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7篇 您的检索式:作者名="Moons AHM"
    题名 作者 年代 出处 被引量
1胶质瘤的基因治疗(英文)显示文摘Glioblastoma multiforme(GBM) is a highly invasive brain tumour that is unvaryingly fatal in humans despite even aggressive therapeutic approaches such as surgical resection followed by chemotherapy and radiotherapy.Unconventional treatment options such as gene therapy provide an intriguing option for curbing glioma related deaths.To date,gene therapy has yielded encouraging results in preclinical animal models as well as promising safety profiles in phase I clinical trials,but has failed to demonstrate significant therapeutic efficacy in phase III clinical trials.The most widely studied antiglioma gene therapy strategies are suicide gene therapy,genetic immunotherapy and oncolytic virotherapy,and we have attributed the challenging transition of these modalities into the clinic to four major roadblocks:(1) anatomical features of the central nervous system,(2) the host immune system,(3) heterogeneity and invasiveness of GBM and(4) limitations in current GBM animal models.In this review,we discuss possible ways to jump these hurdles and develop new gene therapies that may be used alone or in synergy with other modalities to provide a powerful treatment option for patients with GBM.Tobias A Ahmed A Moon KS Lesniak MS. 2013中华神经外科疾病研究杂志2013,12,4:16
2Tissue factor and coronary artery disease显示文摘Moons AHM Levi M Peters RJG 2002Cardiovasc Res2002,53,:1
3Prehospital neurologie deterioration in patients with intraeerebral hemorrhage显示文摘MOON JS JANIUA N AHMED S 2008Crit Care Med2008,36,1:1
4Re- combinant nematode anticoagulant protein c2, an in- hibitor of the tissue factor/factor V H a complex, in patients undergoing elective coronary angioplasty Ap- pendix FREE 显示文摘Moons AHM Peters RGJ Bijsterveld NR 2003J Am Coll Cardiol2003,41,12:1
5Nano-embossed structure on polypropylene induced by low energy Ar ion beam irradiation显示文摘Sk. Faruque Ahmed Geon-Ho Rho Ji Yeong Lee Seong Jin Kim Ho-Young Kim Yong-Jun Jang Myoung-Woon Moon Kwang-Ryeol Lee 2010Surface & Coatings Technology2010,,:1
6Perovskite–Nitrogen‐Doped Carbon Nanotube Composite as Bifunctional Catalysts for Rechargeable Lithium–Air Batteries显示文摘Hey Woong Park Dong Un Lee Moon Gyu Park Raihan Ahmed Min Ho Seo Linda F. Nazar Zhongwei Chen 2015ChemSusChem2015,,6:1
7Enhancement of elec- tron field emission property with silver incorporation into di- amond-like carbon matrix 显示文摘AHMED S F MOON M W LEE K R 2008Applied Physics Letters2008,92,:1
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