|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Challenges in the diagnosis and treatment of gestational trophoblastic neoplasia worldwide显示文摘Gestational trophoblastic neoplasia(GTN) is a rare tumor that originates from pregnancy that includes invasive mole, choriocarcinoma(CCA), placental site trophoblastic tumor and epithelioid trophoblastic tumor(PSTT/ETT). GTN presents different degrees of proliferation, invasion and dissemination, but, if treated in reference centers, has high cure rates, even in multi-metastatic cases.The diagnosis of GTN following a hydatidiform molar pregnancy is made according to the International Federation of Gynecology and Obstetrics(FIGO)2000 criteria: four or more plateaued human chorionic gonadotropin(hCG)concentrations over three weeks; rise in hCG for three consecutive weekly measurements over at least a period of 2 weeks or more; and an elevated but falling hCG concentrations six or more months after molar evacuation. However,the latter reason for treatment is no longer used by many centers. In addition,GTN is diagnosed with a pathological diagnosis of CCA or PSTT/ETT. For staging after a molar pregnancy, FIGO recommends pelvic-transvaginal Doppler ultrasound and chest X-ray. In cases of pulmonary metastases with more than 1cm, the screening should be complemented with chest computed tomography and brain magnetic resonance image. Single agent chemotherapy, usually Methotrexate(MTX) or Actinomycin-D(Act-D), can cure about 70% of patients with FIGO/World Health Organization(WHO) prognosis risk score ≤ 6(low risk), reserving multiple agent chemotherapy, such as EMA/CO(Etoposide,MTX, Act-D, Cyclophosphamide and Oncovin) for cases with FIGO/WHO prognosis risk score ≥ 7(high risk) that is often metastatic. Best overall cure rates for low and high risk disease is close to 100% and > 95%, respectively. The management of PSTT/ETT differs and cure rates tend to be a bit lower. The early diagnosis of this disease and the appropriate treatment avoid maternal death,allow the healing and maintenance of the reproductive potential of these women. | Antonio Braga Paulo Mora Andréia Cristina de Melo Angélica Nogueira-Rodrigues Joffre Amim-Junior Jorge Rezende-Filho Michael J Seckl | 2019 | World Journal of Clinical Oncology2019，10，2： | 15 |
| 2 | Acute effects of physical exercise in type 2 diabetes: A review显示文摘The literature has shown the efficiency of exercise in the control of type 2 diabetes(T2D), being suggested as one of the best kinds of non-pharmacological treatments for its population. Thus, the scientific production related to this phenomenon has growing exponentially. However, despite its advances, still there is a lack of studies that have carried out a review on the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in individuals with T2 D, not to mention that in a related way, these themes have been very little studied today. Therefore, the aim of this study was to organize and analyze the current scientific production about the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in T2 D individuals. For such, a research with the following keywords was performed:-exercise; diabetes and post-exercise hypotension; diabetes and excess post-exercise oxygen consumption; diabetes and acute effects in PUBMED, SCIELO and HIGHWIRE databases. From the analyzed studies, it is possible to conclude that, a single exercise session can promote an increase in the bioavailability of nitric oxide and elicit decreases in postexercise blood pressure. Furthermore, the metabolic stress from physical exercise can increase the oxidation of carbohydrate during the exercise and keep it, in high levels, the post exercise consumption of O2, this phenomenon increases the rate of fat oxidation during recovery periods after exercise, improves glucose tolerance and insulin sensitivity and reduces glycemia between 2-72 h, which seems to be dependent on the exercise intensity and duration of the effort. | Ricardo Yukio Asano Marcelo Magalhes Sales Rodrigo Alberto Vieira Browne José Fernando Vila Nova Moraes Hélio José Coelho Júnior Milton Rocha Moraes Hebert Gustavo Simoes | 2014 | World Journal of Diabetes2014，5，5： | 8 |
| 3 | Chemical activation of carbon mesophase pitches 显示文摘 | MORA E BLANCO C PAJARES J A | 2006 | J Colloid Interface Sci2006，298，1： | 1 |
| 4 | Digestion of biological materials using the microwave-assisted sample combustion technique 显示文摘 | Mesko M F Moraes D P Barin J S Dressler V L Knapp G Flores E M M | 2006 | Microchem Journal2006，82，： | 1 |
| 5 | Diabetes inflammation,proinflam-matory cytokines and diabetic nephropathy显示文摘 | Navarro J F Mora C | 2006 | ScientificWorld J2006，6，： | 1 |
| 6 | Schistosoma mansoni: In vitro schistosomicidal activity ofpiplartine 显示文摘 | de Moraes J Nascimento C Lopes P O M V | 2011 | Exp Parasitol2011，127，2： | 1 |
| 7 | Genome-wide analysis of gene expression associated with MYCN in human neuroblastoma显示文摘 | Alaminos M Mora J Cheung NK Smith A Qin J Chen L Gerald WL | 2003 | Cancer Res2003，63，8： | 1 |
| 8 | Stabilityof the ANAMMOX process in a gas - lift reactor and a SBR 显示文摘 | Dapena - Mora A Campos J L Mosquera - Corral A | 2004 | journal of Biotechnology2004，110，2： | 1 |
| 9 | Optimiza- tion of wind farm turbines layout using an evolutive algorithm 显示文摘 | Gonzalez J S Rodriguez A G G Mora J C | 2010 | Renewable Energy2010，35，8： | 1 |
| 10 | Code validation for high-speed flow simulation over satellite launch vehicle 显示文摘 | Azevedo J L F Moraes P Jr | 1996 | Journal of Spacecraft and Rockets1996，30，1： | 1 |
| 11 | Prevention of endotoxin-induced systemic response by bone marrow-derived mes-enchymal stem cells in mice 显示文摘 | Xu J Woods CR Mora AL | 2007 | Am J Physiol Lung Cell Mol Physiol2007，293，1： | 1 |
| 12 | High-Fat Diet Induces Apoptosis of Hypothalamic Neurons显示文摘 | Moraes JC Coope A Morari J | | 0，，04： | 1 |
| 13 | Adoption and use of precision agriculture technologies in the sugarcane industry of Sao Paulo state,Brazil显示文摘 | SILVA C B DE MORAES A F D MOLIN J P | 2011 | Precision Agric2011，12，： | 1 |
| 14 | A randomized controlled trial comparing vaginal misoprostol versus Foley catheter plus oxytocin for labor induction 显示文摘 | MORAES FILHO O B ALBUQUERQUE R M CECATYI J G | 2010 | Acta Obstetricia et Gyriecologica Scandinavica2010，89，8： | 1 |
| 15 | The fluid dynamics of taylor cones显示文摘 | Mora J F | 2007 | Annual Review of Fluid Mechanics2007，39，： | 1 |
| 16 | Role of inflammation in diabetic complication 显示文摘 | NAVARRO J F MORA C | 2005 | Nephrol Dial Transplant2005，20，： | 1 |
| 17 | High-fat diet induces apoptosis of hypothalamic neurons显示文摘 | Moraes JC Coope A Morari J | 2009 | PLoS One2009，4，4： | 1 |
| 18 | Application of microwave induced combustion in closed vessels for carbon black-containing elastomers decomposition 显示文摘 | Moraes D P Mesko M F Mello P A Paniz J N G Dressler V L Knapp G Flores E M M | 2007 | Spectrochim Acta : Part B2007，62，： | 1 |
| 19 | Prognstic value of inverted apilloma of the lower urinary tract显示文摘 | Nunez Mora C Rios Gonzalez E Garcia Mediero J M | 2001 | Arch Esp Urol2001，54，1： | 1 |
| 20 | Detection of proteins encoded by the pre-S region of hepatitis B virus in the sera of HBsAg carriers:relation to viral replication显示文摘 | Ibarra MZ Mora I Bartolome J | 1989 | Liver1989，9，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员