|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Oral purgative and simethicone before small bowel capsule endoscopy显示文摘AIM:To evaluate small bowel cleansing quality,diagnostic yield and transit time,comparing three cleansing protocols prior to capsule endoscopy.METHODS:Sixty patients were prospectively enrolled and randomized to one of the following cleansing protocols:patients in Group A underwent a 24 h liquid diet and overnight fasting;patients in Group B followed protocol A and subsequently were administered 2 L of polyethylene glycol(PEG) the evening before the procedure;patients in Group C followed protocol B and were additionally administered 100 mg of simethicone 30 min prior to capsule ingestion.Small bowel cleansing was independently assessed by two experienced endoscopists and classified as poor,fair,good or excellent according to the proportion of small bowel mucosa under perfect conditions for visualization.When there was no agreement between the two endoscopists,the images were reviewed and discussed until a consensus was reached.The preparation was considered acceptable if > 50% or adequate if > 75% of the mucosa was in perfect cleansing condition.The amount of bubbles was assessed independently and it was considered significant if it prevented a correct interpretation of the images.Positive endoscopic findings,gastric emptying time(GET) and small bowel transit time(SBTT) were recorded for each examination.RESULTS:There was a trend favoring Group B in achieving an acceptable(including fair,good or excellent) level of cleansing(Group A:65%;Group B:83.3%;Group C:68.4%) [P = not significant(NS)] and favoring Group C in attaining an excellent level of cleansing(Group A:10%;Group B:16.7%;Group C:21.1%)(P = NS).The number of patients with an adequate cleansing of the small bowel,corresponding to an excellent or good classification,was 5(25%) in Group A,5(27.8%) in Group B and 4(21.1%) in Group C(P = 0.892).Conversely,7 patients(35%) in Group A,3 patients(16.7%) in Group B and 6 patients(31.6%) in Group C were considered to have poor small bowel cleansing(P = 0.417),with significant fluid or debris such that the examination was unreliable.The proportion of patients with a significant amount of bubbles was 50% in Group A,27.8% in Group B and 15.8% in Group C(P = 0.065).This was significantly lower in Group C when compared to Group A(P = 0.026).The mean GET was 27.8 min for Group A,27.2 min for Group B and 40.7 min for Group C(P = 0.381).The mean SBTT was 256.4 min for Group A,256.1 min for Group B and 258.1 min for Group C(P = 0.998).Regarding to the rate of complete examinations,the capsule reached the cecum in 20 patients(100%) in Group A,16 patients(88.9%) in Group B and 17 patients(89.5%) in Group C(P = 0.312).A definite diagnosis based on relevant small bowel endoscopic lesions was established in 60% of the patients in Group A(12 patients),44.4% in Group B(8 patients) and 57.8% in Group C(11 patients)(P = 0.587).CONCLUSION:Preparation with 2 L of PEG before small bowel capsule endoscopy(SBCE) may improve small bowel cleansing and the quality of visualization.Simethicone may further reduce intraluminal bubbles.No significant differences were found regarding GET,SBTT and the proportion of complete exploration or diagnostic yield among the three different cleansing protocols. | Bruno Joel Ferreira Rosa Mara Barbosa Joana Magalhes Ana Rebelo Maria Joo Moreira José Cotter | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，2： | 21 |
| 2 | Pediatric primary urolithiasis: Symptoms, medical management and prevention strategies显示文摘In the past few decades pediatric urolithiasis has become more frequent. The reason for this increase is not completely clear but has been attributed to changes in climate, nutritional habits and possibly other environmental factors. Although less frequent than adult stone disease, urolithiasis in the pediatric age group is also related to significant morbidity, particularly since stones tend to recur, and, thus, should not be underestimated. Most children with idiopathic stone disease have an underlying metabolic abnormality substantiating the importance of metabolic evaluation already following initial diagnosis of urolithiasis. Identification of the metabolic abnormality allows for more specific prescription of non pharmacological and pharmacological interventions aimed at preventing recurrent stone formation. A better understanding of the causes of kidney stone disease will provide better strategies for stone prevention in children. | Maria Goretti Moreira Guimar?es Penido Marcelo de Sousa Tavares | 2015 | World Journal of Nephrology2015，4，4： | 4 |
| 3 | Finding the solution for incomplete small bowel capsule endoscopy显示文摘AIM:To evaluate whether the use of real time viewer(RTV)and administration of domperidone to patients with delayed gastric passage of the capsule could reduce the rate of incomplete examinations(IE)and improve the diagnostic yield of small bowel capsule endoscopy(SBCE).METHODS:Prospective single center interventional study,from June 2012 to February 2013.Capsule location was systematically checked one hour after ingestion using RTV.If it remained in the stomach,the patient received 10 mg domperidone per os and the location of the capsule was rechecked after 30 min.If the capsule remained in the stomach a second dose of10 mg of domperidone was administered orally.After another 30 min the position was rechecked and if the capsule remained in the stomach,it was passed into the duodenum by upper gastrointestinal(GI)endoscopy.The rate of IE and diagnostic yield of SBCE were compared with those of examinations performed before the use of RTV or domperidone in our Department(control group,January 2009-May 2012).RESULTS:Both groups were similar regarding age,sex,indication,inpatient status and surgical history.The control group included 307 patients,with 48(15.6%)IE.The RTV group included 82 patients,with3(3.7%)IE,P=0.003.In the control group,average gastric time was significantly longer in patients with IE than in patients with complete examination of the small bowel(77 min vs 26 min,P=0.003).In the RTV group,the capsule remained in the stomach one hour after ingestion in 14/82 patients(17.0%)vs 48/307(15.6%)in the control group,P=0.736.Domperidone did not significantly affect small bowel transit time(260min vs 297 min,P=0.229).The capsule detected positive findings in 39%of patients in the control group and 49%in the RTV group(P=0.081).CONCLUSION:The use of RTV and selective administration of domperidone to patients with delayed gastric passage of the capsule significantly reduces incomplete examinations,with no effect on small bowel transit time or diagnostic yield. | José Cotter Francisca Dias de Castro Joana Magalhes Maria Joo Moreira Bruno Rosa | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，12： | 4 |
| 4 | Metabolic Syndrome and Central Fat Distribution Are Related to Lower Serum Osteocalcin Concentrations显示文摘 | Bezerra Dos Santos Magalh?es Karina Moreira Magalh?es Marcelo Trov?o Diniz Erik Salgado Lucena Cynthia Griz Luiz Bandeira Francisco | 2013 | Annals of Nutrition & Metabolism2013，，3： | 1 |
| 5 | Construction of an artifact to the suitability of sitting posture in children with cere- bral palsy and multiple disabilities显示文摘 | Schewtschik AC de Oliveira ES de Vasconcelos Moreira I | 2013 | Disabil Re- habil Assist Technol2013，8，6： | 1 |
| 6 | Polymorphisms in the TNFA and IL6 genes represent risk factors for autoimmune thyroid disease显示文摘 | Dur(a)es C Moreira CS Alvelos I | 2014 | PLoS One2014，9，10： | 1 |
| 7 | On the formulation of pH-sensitive liposomes with long circulation times显示文摘 | SIMES S MOREIRA J N FONSECA C | 2004 | Adv Drug Deliv Rev2004，56，7： | 1 |
| 8 | Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin显示文摘 | Moreira ES Wiltshire TJ Faulkner G | 2000 | Nature Genet2000，24，： | 1 |
| 9 | Telethonin protein expression in neuromuscular disorders显示文摘 | Vainzof M Moreira ES Suzuki OT | 2002 | Biochim Biophys Acta2002，1588，： | 1 |
| 10 | Bone disease in pediatric idiopathic hypercalciuria显示文摘Idiopathic hypercalciuria(IH) is the leading metabolic risk factor for urolithiasis and affects all age groups without gender or race predominance. IH has a high morbidity with or without lithiasis and reduced bone mineral density(BMD), as described previously in pediatric patients as well as in adults. The pathogenesis of IH is complex and not completely understood, given that urinary excretion of calcium is the end result of an interplay between three organs(gut, bone and kidney), which is further orchestrated by hormones, such as 1,25 dihydroxyvitamin D, parathyroid hormone, calcitonin and fosfatonins(i.e., fibroblast growth-factor-23). Usually, a primary defect in one organ induces compensatory mechanisms in the remaining two organs, such as increased absorption of calcium in the gut secondary to a primary renal loss. Thus, IH is a systemic abnormality of calcium homeostasis with changes in cellular transport of this ion in intestines, kidneys and bones. Reduced BMD has been demonstrated in pediatric patients diagnosed with IH. However, the precise mechanisms of bone loss or failure of adequate bone mass gain are still unknown. The largest accumulation of bone mass occurs during childhood and adolescence, peaking atthe end of the second decade of life. This accumulation should occur without interference to achieve the peak of optimal bone mass. Any interference may be a risk factor for the reduction of bone mass with increased risk of fractures in adulthood. This review will address the pathogenesis of IH and its consequence in bone mass. | Maria Goretti Moreira Guimares Penido Marcelo de Sousa Tavares | 2012 | World Journal of Nephrology2012，1，2： | 1 |
| 11 | Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin显示文摘 | Moreira ES Wiltshire TJ Faulkner G | 2000 | Nat Genet2000，24，2： | 1 |
| 12 | Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin显示文摘 | Moreira ES Wiltshire T J Faulkner G | 2000 | Nat Genet2000，24，： | 1 |
| 13 | Antioxidants modulate the antiproliferative effects of nitric oxide on vascular smooth muscle cells and adventitial fibroblasts by regulating oxidative stress显示文摘 | Gregory EK Vavra AK Moreira ES | 2011 | Am J Surg2011，202，5： | 1 |
| 14 | Hydrolysis of oligosaccharides in soybean products by Debaryomyces hansenii UFV-1 α-galactosidases显示文摘 | Pollyanna Amaral Viana Sebasti?o Tavares de Rezende Daniel Luciano Falkoski Thiago de Almeida Leite Inês Chamel José Maurílio Alves Moreira Valéria Monteze Guimar?es | 2006 | Food Chemistry2006，，2： | 1 |
| 15 | Is It Possible to Predict the Presence of Intestinal Angioectasias?显示文摘 | Tiago Cúrdia Gon?alves Joana Magalh?es Pedro Boal Carvalho Maria Jo?o Moreira Bruno Rosa José Cotter Spiros D. Ladas | 2014 | Diagnostic and Therapeutic Endoscopy2014，，： | 1 |
| 16 | Autosomal recessive limb-girdle muscular dystrophy,LGMD2F is caused by a mutation in the δ-sarcoglycan gene显示文摘 | Nigro V Moreira ES Piluso G | 1996 | Nature Genet1996，14，3： | 1 |
| 17 | The seventh form of autoso- real recessive limb -girdle muscular dystrophy is mapped to 17q11 - 12显示文摘 | Moreira ES Vainzof M Marie SK | 1997 | Am J Hum Genet1997，61，： | 1 |
| 18 | Coronary fistula to the right atrium: a challenge for the interventional cardiologist 显示文摘 | Gonqalves ES Moura CC Moreira JA | 2013 | Rev Port Cardiol2013，32，3： | 1 |
| 19 | Limb - girdle muscu- lar dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin显示文摘 | Moreira ES Wiltshire TJ Faulkner G | 2000 | Nat Genet2000，24，： | 1 |
| 20 | A Polymorphism in the Promoter Region of the Selenoprotein S Gene (SEPS1) Contributes to Hashimoto?s Thyroiditis Susceptibility显示文摘 | Liliana R. Santos Cecília Dur?es Adélia Mendes Hugo Prazeres Maria Inês Alvelos Carla Susete Moreira Paulo Canedo César Esteves Celestino Neves Davide Carvalho Manuel Sobrinho-Sim?es Paula Soares | 2014 | The Journal of Clinical Endocrinology & Metabolism2014，，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员