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| 1 | Regulating the stability of TGFβ receptors and Smads显示文摘转变生长因素尾(TGF 尾) 在胚胎、成年的纸巾控制细胞的行为。对血浆膜上的 serine/threonine kinase 受体有约束力的 TGF 尾激活 Smad 分子和另外的发信号蛋白质一起调整基因表示。在瞄准 TGF 下游地解释在发信号的网络的几个部件之间的协作的这评论,机制和模型,尾被介绍。我们讨论 TGF 尾 receptor/Smad 发信号的活动和持续时间怎么能被在小径影响关键蛋白质的稳定性的 translational 以后修正调整。我们加亮在这些机制和人的疾病之间的连接,例如组织纤维变性和癌症。 | Peter Lonn Anita Moren Erna Raja Markus Dahl Aristidis Moustakas | 2009 | Cell Research2009,19,1: | 39 |
| 2 | Metabolic inflammation as an instigator of fibrosis during nonalcoholic fatty liver disease显示文摘Non-alcoholic fatty liver disease(NAFLD)is characterized by excessive storage of fatty acids in the form of triglycerides in hepatocytes.It is most prevalent in western countries and includes a wide range of clinical and histopathological findings,namely from simple steatosis to steatohepatitis and fibrosis,which may lead to cirrhosis and hepatocellular cancer.The key event for the transition from steatosis to fibrosis is the activation of quiescent hepatic stellate cells(qHSC)and their differentiation to myofibroblasts.Pattern recognition receptors(PRRs),expressed by a plethora of immune cells,serve as essential components of the innate immune system whose function is to stimulate phagocytosis and mediate inflammation upon binding to them of various molecules released from damaged,apoptotic and necrotic cells.The activation of PRRs on hepatocytes,Kupffer cells,the resident macrophages of the liver,and other immune cells results in the production of proinflammatory cytokines and chemokines,as well as profibrotic factors in the liver microenvironment leading to qHSC activation and subsequent fibrogenesis.Thus,elucidation of the inflammatory pathways associated with the pathogenesis and progression of NAFLD may lead to a better understanding of its pathophysiology and new therapeutic approaches. | Angeliki Katsarou Ioannis I Moustakas Iryna Pyrina Panagiotis Lembessis Michael Koutsilieris Antonios Chatzigeorgiou | 2020 | World Journal of Gastroenterology2020,26,17: | 9 |
| 3 | Free Oxide Distribution in Poorly and Well Drained Soils Developed on Calcareous Alluvial Deposits显示文摘A study on the distribution of free iron and manganese oxides was conducted in soils developed on calcareous alluvial deposits under subhumid climatic conditions, in Western Greece. Soil samples from two well drained soils and from two poorly drained soils, classified as Alfisols, were collected and used in this study. After certification of soil homogeneity the acid ammonium oxalate and dithionite-citrate-bicarbonate methods were used to extract free iron and manganese oxides from the samples. Iron oxides extracted by the dithionite-citrate-bicarbonate method (Fed) were significantly higher than the iron oxides extracted by the ammonium oxalate method (Feo), indicating that a considerable fraction is present in crystalline forms,independent of drainage status. A confirmation of free iron oxides and fine clay was detected. The ratios Feo/Fed and (Fed-Feo)/total Fe (Fet) could not be used to distinguish the well drained soils from the poorly drained soils. Manganese movement in a soluble form is independent of the fine clay. | N. K. MOUSTAKAS P. E. BAROUCHAS | 2003 | Pedosphere2003,13,4: | 3 |
| 4 | The impacts over time of marine protected areas: A null model显示文摘 | William Silvert Aristides Moustakas | 2011 | Ocean and Coastal Management2011,,4: | 2 |
| 5 | High reflectivity and broad bandwidth AlN/GaN distributed Bragg reflectors grown by molecular-beam epitaxy 显示文摘 | H M Ng T D Moustakas S N G Chu | 2000 | Applied Physics Letters2000,76,20: | 1 |
| 6 | ALuminum stress induces up-regulation of an efficient antioxidant system in the Al-tolerant maize Line but not in the Al-sensitive显示文摘 | GIANNAKOULAA A MOUSTAKAS M SYROS T | 2010 | Environmental and E3'perimental Botany2010,67,48: | 1 |
| 7 | LIM-kinase 2 and cofilin phosphorylation mediate actin cytoskeleton reorganization induced by transforming growth factor-beta显示文摘 | Vardouli L Moustakas A Stoumaras C | 2005 | J Biol Chem2005,280,11: | 1 |
| 8 | The regulation of TGFbeta signal transduction显示文摘 | Moustakas A Heldin CH | 2009 | Development2009,136,22: | 1 |
| 9 | Measuring occupation- al stress and HRA Axis dysregulation among healthy workers by salivary cortisol levels显示文摘 | Moustaka E Malliarou M Constantinidis TC | 2015 | Br J Med Med Res2015,6,11: | 1 |
| 10 | Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression显示文摘 | Moustakas A Heldin CH | 2007 | Cancer Sci2007,98,10: | 1 |
| 11 | Actions of TGF-β as tumor suppressor andpro-metastatic factor in human cancer 显示文摘 | Pardali K Moustakas A | 2007 | Biochim Biophys Acta2007,1775,1: | 1 |
| 12 | Growth and device applications of Ⅲ-nitrides by MBE显示文摘 | MOUSTAKAS T D ILIOPOULOS E SAMPATH A V | 2001 | J Cryst Growth2001,,: | 1 |
| 13 | Regulation of actin organisation by TGF-- beta in H -- ras-- transformed fibroblasts 显示文摘 | Moustakas A Stournaras C | 1999 | J Cell Sei1999,112,8: | 1 |
| 14 | Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer显示文摘 | Pardali K Moustakas A | 2007 | Biochim Biophys Acta2007,1775,1: | 1 |
| 15 | Smad regulation in TGF-βsignaling transduction显示文摘 | Moustakas A Souchelnytskyi S Heldin C H | 2001 | J Cell Sci2001,114,24: | 1 |
| 16 | Smad regulation in TGF-p signal transduction显示文摘 | Moustakas A Souchelnytskyi S Heldin C H | | 0,,24: | 1 |
| 17 | Inorganic-organic Core-shell Titania Nanopartieles for Efficient Visible Light Activated Photocatalysis 显示文摘 | Moustakas N G Kontos A G Likodimos V | 2013 | Applied CatalysL B : Envirnnmental2013,13,: | 1 |
| 18 | Smad regulation in TGF-beta signal transduction显示文摘 | Moustakas A Souchelnytskyi S Heldin CH | 2001 | J Cell Sci2001,114,24: | 1 |
| 19 | Role of Smads in TGFI5 signaling 显示文摘 | Heldin CH Moustakas A | 2012 | Cell Tissue Res2012,347,1: | 1 |
| 20 | Physiological and ultrastructural effect of cadmium on wheat( Trticum aestivum C )leaves显示文摘 | Ouzounidou G Moustakas M Eleftheriou E P | 1997 | Archives of Environmental Contamination and Toxicology1997,32,2: | 1 |