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| 1 | Effectiveness of probiotics in irritable bowel syndrome:Updated systematic review with meta-analysis显示文摘AIM:To investigate the efficacy of probiotics in irritable bowel syndrome(IBS) patients.METHODS:Pub Med,Cochrane library,Scopus,Google Scholar,and Clinicaltrial.gov databases were searched for literature published between September 2007 and December 2013.The applied Mesh terms were 'probiotics,' 'irritable bowel syndrome,' and 'irritable bowel syndrome treatment.' The collected data contained24 clinical trials,of which 15 were eligible for meta-analysis and nine were reviewed systematically.All studies were randomized placebo-controlled trials in patients with IBS that investigated the efficacy of probiotics in IBS improvement.The Jadad score was used to assess the methodological quality of trials.The quality scale ranges from 0 to 5 points,with a score ≤ 2 indicating a low quality report,and a score of ≥3 indicating a high quality report.Relative risk(RR),standardized effect size,and 95%CI were calculated using the Der Simonian-Laird method.The Cochran Q test was used to test heterogeneity with P < 0.05.Funnel plots were constructed and Egger's and BeggMazumdar tests were performed to assess publication bias.RESULTS:A total of 1793 patients were included in the meta-analysis.The RR of responders to therapies based on abdominal pain score in IBS patients for two included trials comparing probiotics to placebo was 1.96(95%CI:1.14-3.36;P = 0.01).RR of responders to therapies based on a global symptom score in IBS patients for two included trials comparing probiotics with placebo was 2.43(95%CI:1.13-5.21;P = 0.02).For adequate improvement of general symptoms in IBS patients,the RR of seven included trials(six studies) comparing probiotics with placebo was 2.14(95%CI:1.08-4.26;P = 0.03).Distension,bloating,and flatulence were evaluated using an IBS severity scoring system in three trials(two studies) to compare the effect of probiotic therapy in IBS patients with placebo,the standardized effect size of mean differences for probiotics therapy was-2.57(95%CI:-13.05--7.92).CONCLUSION:Probiotics reduce pain and symptom severity scores.The results demonstrate the beneficial effects of probiotics in IBS patients in comparison with placebo. | Tina Didari Shilan Mozaffari Shekoufeh Nikfar Mohammad Abdollahi | 2015 | World Journal of Gastroenterology2015，21，10： | 51 |
| 2 | Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis显示文摘AIM: To investigate the beneficial effect of the combination of butyrate, Lactobacillus casei, and L-carnitine in a rat colitis model.METHODS: Rats were divided into seven groups. Fourgroups received oral butyrate, L-carnitine, Lactobacillus casei and the combination of three agents for 10 consecutive days. The remaining groups included negative and positive controls and a sham group. Macroscopic, histopathological examinations, and biomarkers such as tumor necrosis factor-alpha(TNF-α) and interlukin-1β(IL-1β), myeloperoxidase(MPO), thiobarbituric acid reactive substances(TBARS), and ferric reduced ability of plasma(FRAP) were determined in the colon.RESULTS: The combination therapy exhibited a significant beneficial effect in alleviation of colitis compared to controls. Overall changes in reduction of TNF-α(114.66 ± 18.26 vs 171.78 ± 9.48 pg/mg protein, P < 0.05), IL-1β(24.9 ± 1.07 vs 33.06 ± 2.16 pg/mg protein, P < 0.05), TBARS(0.2 ± 0.03 vs 0.49 ± 0.04 μg/mg protein, P < 0.01), MPO(15.32 ± 0.4 vs 27.24 ± 3.84 U/mg protein, P < 0.05), and elevation of FRAP(23.46 ± 1.2 vs 15.02 ± 2.37 μmol/L, P < 0.05) support the preference of the combination therapy in comparison to controls. Although the monotherapies were also effective in improvement of colitis markers, the combination therapy was much better in improvement of colon oxidative stress markers including FRAP, TBARS, and MPO.CONCLUSION: The present combination is a suitable mixture in control of experimental colitis and should be trialed in the clinical setting. | Mahsa Moeinian Seyedeh Farnaz Ghasemi-Niri Shilan Mozaffari Amir Hossein Abdolghaffari Maryam Baeeri Mona Navaea-Nigjeh Mohammad Abdollahi | 2014 | World Journal of Gastroenterology2014，20，31： | 5 |
| 3 | New biologic therapeutics for ulcerative colitis and Crohn’s disease显示文摘 | Shilan Mozaffari Shekoufeh Nikfar Amir Hossein Abdolghaffari Mohammad Abdollahi | 2014 | Expert Opinion on Biological Therapy2014，，5： | 3 |
| 4 | A systematic review of the safety of probiotics显示文摘 | Tina Didari Sara Solki Shilan Mozaffari Shekoufeh Nikfar Mohammad Abdollahi | 2014 | Expert Opinion on Drug Safety2014，，2： | 3 |
| 5 | Melatonin, a Promising Supplement in Inflammatory Bowel Disease: A Comprehensive Review of Evidences显示文摘 | Shilan Mozaffari Mohammad Abdollahi | 2011 | Current Pharmaceutical Design2011，，38： | 2 |
| 6 | Real-time immune-inspired optimum state-of-charge trajectory estimation using upcoming route information preview and neural networks for plug-in hybrid electric vehicles fuel economy显示文摘当前的调查的主要提议是开发能被用于最佳电池 state-of-charge (SOC ) 的即时评价的一个计算基于智力的框架在插件混血儿的轨道电的车辆(PHEV ) 。估计的 SOC 轨道然后能被采用让一个聪明的力量管理显著地改进车辆的燃料经济。设计聪明的 SOC 轨道建筑者利用即将来临的线路信息预览完成电和石块燃料的最低可能的全部的费用。减少即时优化的复杂性,作者建议允许把线路信息分成片断的一个预定义的数字的一条有免疫力的基于系统的聚类途径。聪明的即时优化器也在生物免疫系统根据相互作用被启发,并且被称为人工的有免疫力的算法(AIA ) 。优化器的客观函数从被从在 Autonomie 软件造的车辆的一个高保真模型获得的一个数据库训练的一个计算地有效的人工的神经网络(ANN ) 被导出。模拟结果证明免疫者的集成启发了聚类工具, AIA 和 ANN,将导致能为基线车辆产生一条近全球的最佳 SOC 轨道的一个强大的框架,也就是说丰田 Prius PHEV。当前的调查的结果证明由利用聪明的途径,为 PHEV 的聪明的力量管理设计一个计算地有效、强大的 SOC 轨道建筑者是可能的。 | Ahmad MOZAFFARI Mahyar VAJEDI Nasser L. AZAD | 2015 | Frontiers of Mechanical Engineering2015，10，2： | 2 |
| 7 | Canonical Workflows to Make Data FAlR显示文摘The FAIR principles have been accepted globally as guidelines for improving data-driven science and data management practices,yet the incentives for researchers to change their practices are presently weak.In addition,data-driven science has been slow to embrace workflow technology despite clear evidence of recurring practices.To overcome these challenges,the Canonical Workflow Frameworks for Research(CWFR)initiative suggests a large-scale introduction of self-documenting workflow scripts to automate recurring processes or fragments thereof.This standardised approach,with FAIR Digital Objects as anchors,will be a significant milestone in the transition to FAIR data without adding additional load onto the researchers who stand to benefit most from it.This paper describes the CWFR approach and the activities of the CWFR initiative over the course of the last year or so,highlights several projects that hold promise for the CWFR approaches,including Galaxy,Jupyter Notebook,and RO Crate,and concludes with an assessment of the state of the field and the challenges ahead. | Peter Wittenburg Alex Hardisty Yann Le Franc Amirpasha Mozaffari Limor Peer Nikolay A.Skvortsov Zhiming Zhao Alessandro Spinuso | 2022 | Data Intelligence2022，4，2： | 2 |
| 8 | Wheat grain yield response to phosphorus fertilizer rate显示文摘 | Slaton N A DeLong R E Mozaffari M | 2005 | Sabbe Arkansas Soil Fertility Studies2005，537，： | 1 |
| 9 | Myocardial ischemic-reperfusion in-jury in a rat model of metabolic syndrome显示文摘 | Mozaffari MS Schaffer SW | 2008 | Obesity(SilverSpring)2008，16，10： | 1 |
| 10 | Application of the Energy Balance Method to Nonlinear Vibrating Equations 显示文摘 | MEHDIPOUR I GANJI D D MOZAFFARI M | 2010 | Current Applied Physics2010，10，： | 1 |
| 11 | Effects of Hypericum perforatum extract on rat irritable bowel syndrome显示文摘 | Mozaffari S Esmaily H Rahimi R | 2011 | Pharmacogn Mag2011，7，27： | 1 |
| 12 | Preva- lence of ESBL and MBL encoding genes in Aeinetobaeter baumannii strains isolated from patients of intensive care units(ICU) 显示文摘 | Safari M Mozaffari Nejad AS Bahador A | 2015 | Saudi J Biol Sci2015，22，4： | 1 |
| 13 | Simultaneous spectrophotometric determination of trace amounts of cobalt,nickel,and copper using the partial least-squares method after the preconcentration of their 2-aminocyclopentene-1-dithiocarboxylate complexes on microcrystalline naphthalene显示文摘 | Gholivand M B Mozaffari Y Sobhani Sh | | 0，，03： | 1 |
| 14 | Role of antioxidant activity of taurine in diabetes显示文摘 | Schaffer SW Azuma J Mozaffari M | 2009 | Can J Physiol Pharmacol2009，87，： | 1 |
| 15 | Renal distal tubule proliferation and increased aquaporin-2 level but decreased urine osmolality in db/db mouse: treatment with chromium picolinatc 显示文摘 | Mozaffari M S Abdelsayed R Liu J Y | 2011 | Exp Mol Pathol2011，92，1： | 1 |
| 16 | Experimental study of thermo-hydraulic and fouling performance of enhanced heat exchangers显示文摘 | Pahlavanzadeh H Jafari Nasr M R Mozaffari S H | 2007 | International Communications in Heat and Mass Transfer2007，34，7： | 1 |
| 17 | Preparation of barium hexafer- rite nanopowders by the sol-gel method, using goethite 显示文摘 | Mozaffari M Taheri M | 2009 | J Magn Magn Mater2009，321，9： | 1 |
| 18 | NK-cell and T-cell functions in patients with breast cancer:effects of surgery and adjuvant chemo-and radiotherapy显示文摘 | Mozaffari F Lindemalm C Choudhury A | 2007 | British J Cancer2007，97，1： | 1 |
| 19 | Role of taurine in thevasculature: an overview of experimental and human studies显示文摘 | Abebe W Mozaffari M S | 2011 | American Journal of Cardiovascular Disease2011，1，3： | 1 |
| 20 | Effects of chronic taurine treatment on reactivity of the rat aorta显示文摘 | Abebe W Mozaffari MS | 2000 | Amino Acids2000，19，34： | 1 |
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