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| 1 | Berry-Phase Oscillations of the Kondo Effect in Single-molecule Magnets显示文摘 | LEUENBERGER M N MUCCIOLO E R | 2006 | Phys Rev Lett2006，97，12： | 1 |
| 2 | Virtual parallel computing and a search algorithm using matrix product states 显示文摘 | CHAMON C MUCCIOLO E R | 2012 | Physical Review Letters2012，109，03： | 1 |
| 3 | PPARgamma in placental angiogenesis显示文摘 | Nadra K Quignodon L Sardella C Joye E Mucciolo A Chrast R | 2010 | Endocrinology2010，151，： | 1 |
| 4 | The dark side of immunotherapy:pancreatic cancer显示文摘Since the journal Science deemed cancer immunotherapy as the“breakthrough of the year”in 2014,there has been an explosion of clinical trials involving immunotherapeutic approaches that,in the last decade-thanks also to the renaissance of the immunosurveillance theory(renamed the three Es theory)-have been continuously and successfully developed.In the latest update of the development of the immuno-oncology drug pipeline,published last November by Nature Review Drug Discovery,it was clearly reported that the immunoactive drugs under study almost doubled in just two years.Of the different classes of passive and active immunotherapies,“cell therapy”is the fastest growing.The aim of this review is to discuss the preclinical and clinical studies that have focused on different immuno-oncology approaches applied to pancreatic cancer,which we assign to the“dark side”of immunotherapy,in the sense that it represents one of the solid tumors showing less response to this type of therapeutic strategy. | Gianluca Mucciolo Cecilia Roux Alessandro Scagliotti Silvia Brugiapaglia FrancescoNovelli Paola Cappello | 2020 | Cancer Drug Resistance2020，3，3： | 1 |
| 5 | Biologic fixation of polyester versus polyurethane covered stents in a porcine model显示文摘 | Marty B Leu AJ Mucciolo A | 2002 | J Vasc Interv Radiol2002，13，： | 1 |
| 6 | Development of new methods for determining the heparanase enzymatic activity显示文摘 | Carina Mucciolo Melo Ivarne Luis Santos Tersariol Helena Bonciani Nader Maria Aparecida Silva Pinhal Marcelo Andrade Lima | 2015 | Carbohydrate Research2015，，： | 1 |
| 7 | A rapid and efficient microwave-assisted synthesis fo hydantoins and thiohydantoins 显示文摘 | MUCCIOLO G G POUPAERT J H | 2003 | Tetrahedron2003，59，8： | 1 |
| 8 | Ovarian follicular dynamics during the estrous cycle in buffalo(Bubalus bubalis)显示文摘 | Baruselli P S Mucciolo R G Visintin J A | 1997 | Theirogenology1997，47，： | 1 |
| 9 | Ovarianfollicular dynamics during the estrus cycle in buffalo (Bubalus buba-lis) ;Preliminary Research显示文摘 | BARUSELU P S MUCCIOLO R G Visintin J A | 1996 | Ann New Y Acad Sci1996，，791： | 1 |
| 10 | Characterization and photoluminescence properties of diglycidyl methacrylic resin doped with the Eu3+-beta-diketonate complex显示文摘 | Mucciolo A Duarte D G | 2006 | Journal of Applied Polymer Science2006，100，1： | 1 |
| 11 | Mosaicism of a novel variant in the ANKRD11 gene in a child with a mild KBG phenotype:A case report显示文摘BACKGROUND KBG syndrome is likely underdiagnosed because of mild and non-specific features in some affected patients especially before the upper permanent central incisors eruption at about the age of 7-8 years.Somatic mosaicisms are usually recognized in the parents only after a typically affected son is diagnosed with KBG syndrome.We describe for the first time the mosaicism of a novel variant in a child with a mild KBG phenotype.CASE SUMMARY Our patient presented at 24 mo of age with short stature,hand abnormalities,facial dysmorphism and mild developmental delay.Pituitary hypoplasia and central hypothyroidism were also detected.By next generation sequencing(NGS)analysis we found a novel deletion in the ANKRD11 gene(c.4880_4893del.),that can be classified as likely pathogenic for the syndrome,with the percentage of mutated allele of 36%.We considered this finding as causative of the mild and non-specific phenotype for KBG syndrome in our patient,as previously reported in adults.A heterozygous variant in HESX1 gene,classified as variant of uncertain significance,but suspected of causing pituitary hypoplasia and hormonal deficiency,was also found.The patient started levothyroxine and growth hormone treatment.CONCLUSION The increased use of NGS analysis may expand the phenotypic spectrum of KBG syndrome because it allows genetic diagnosis of somatic mosaicisms also in children. | Roberto Franceschi Francesca Rivieri Antonio Novelli Daniele Ferretti Adriano Anesi Massimo Soffiati Giulia Porretti Evelina Maines Mafalda Mucciolo Giorgio Radetti | 2023 | World Journal of Medical Genetics2023，11，2： | 0 |
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