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| 1 | Endophytes as Producers of Peptides:An Overview About the Recently Discovered Peptides from Endophytic Microbes显示文摘An endophyte is a fungus or bacterium that lives within a plant in a symbiotic relationship.Extensive colonization of the plant tissue by endophytes creates a barrier effect,where they outcompete and prevent pathogenic organisms from taking hold.This happens by producing secondary metabolites that inhibit the growth of the competitors or pathogens.In this way they play a very important role in the plant defence mechanisms.The metabolites produced by these endophytes fall within a wide range of classes of compounds that include peptides which are the focus of this review.Peptides are increasingly being selected for drug development because they are specific for their targets and have a higher degree of interactions.There have been quite a number of endophytic peptides reported in the recent past indicating that endophytes can be used for the production of peptide based drugs.Molecular screening for NRPS,which shows peptide producing capability,has also shown that endophytes are potential producers of peptides.The presence of NRPS also offers the possibility of genetic modifications which may generate peptides with high pharmacological activities.This review,therefore,aims to show the current status of peptides isolated from endophytic bacteria and fungi in the recent decade.Endophytes as potential sources of peptides according to NRPS studies will also be discussed. | Muna Ali Abdalla Josphat C.Matasyoh | 2014 | Natural Products and Bioprospecting2014，4，5： | 5 |
| 2 | Aquatic toxicity from pulp and paper mill effluents: a review显示文摘 | Muna Ali Sreekrishnan T R | 2001 | Advances in Environmental Research2001，1，： | 1 |
| 3 | Aquatic toxicity from pulp and paper mill effluents: a review显示文摘 | Muna Ali T.R Sreekrishnan | 2001 | Advances in Environmental Research2001，，2： | 1 |
| 4 | Aquatic Toxicity from pulp paper mill effluents : a review 显示文摘 | Muna Ali Sreekrishnan T R | 2001 | Advances in environmental research2001，1，： | 1 |
| 5 | Aquatic toxicity from pulp and paper mill effluents:a review显示文摘 | Ali Muna Sreekrishnan T R | 2001 | Advances in Environmental Research2001，5，： | 1 |
| 6 | Facilitators and barriers to colorectal cancer screening in an outpatient setting显示文摘BACKGROUND Colorectal cancer(CRC)is the third most common cancer and the second leading cause of cancer-related deaths in the United States.Still,1 in 3 adults aged 50 years to 75 years have not been screened for CRC.Early detection and management of precancerous or malignant lesions has been shown to improve overall mortality.AIM To determine the most significant facilitators and barriers to CRC screening in an outpatient clinic in rural North Carolina.The results of this study can then be used for quality improvement to increase the rate of patients ages 50 to 75 who are up to date on CRC screening.METHODS This retrospective study examined 2428 patients aged 50 years to 75 years in an outpatient clinic.Patients were up to date on CRC screening if they had fecal occult blood test or fecal immunochemical test in the past one year,Cologuard in the past three years,flexible sigmoidoscopy/virtual colonoscopy in the past five years,or colonoscopy in the past ten years.Data on patient socioeconomic status,comorbid conditions,and other determinants of health compliance were included as covariates.RESULTS Age[odds ratio(OR)=1.058;P=0.017],no-show rate percent(OR=0.962;P<0.05),patient history of obstructive sleep apnea(OR=1.875;P=0.025),compliance with flu vaccinations(OR=1.673;P<0.05),compliance with screening mammograms(OR=2.130;P<0.05),and compliance with screening pap smears(OR=2.708;P<0.05)were important factors in determining whether a patient will receive CRC screening.Race,gender,insurance or employment status,use of blood thinners,family history of CRC,or other comorbid conditions including diabetes,hypertension,congestive heart failure,chronic obstructive pulmonary disease,and end-stage renal disease were not found to have a statistically significant effect on patient adherence to CRC screening.CONCLUSION Patient age,history of sleep apnea,and compliance with other health maintenance tests were significant facilitators to CRC screening,while no-show rate percent was a significant barrier in our patient population.This study will be of benefit to physicians in addressing and improving the CRC screening rates in our community. | Gbeminiyi Samuel MaryKate Kratzer Oghale Asagbra Josef Kinderwater Shiva Poola Jennifer Udom Karissa Lambert Muna Mian Eslam Ali | 2021 | World Journal of Clinical Cases2021，9，21： | 0 |
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