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| 1 | Implications of hepatic dysfunction in Kawasaki disease:Time-related changes in aspartate aminotransferase, alanine aminotransferase,total bilirubin,and C-reactive protein levels显示文摘Importance:The cause of the hepatic dysfunction that commonly accompanies Kawasaki disease(KD)remains unclear.Objective:We tried to clarify the cause of the hepatic dysfunction.Methods:A total of 381 consecutive patients with acute KD,who had undergone inpatient treatment with intravenous immunoglobulin until the 7th day of illness,were divided into a group of 199 patients with an alanine aminotransferase(ALT)level≥40 IU/L on admission(group I),a group of 52 patients with an ALT level≥40 IU/L at some point after admission(group II),and a group of 130 patients with ALT levels consistently<40 IU/L throughout hospitalization(group III).Aspartate aminotransferase(AST),ALT,total bilirubin(T-Bil),and C-reactive protein(CRP)levels were analyzed over time,and time-courses were compared.results:In the initial stage of illness,in group I,AST,ALT,T-Bil peaked on days 1-3,and AST tended to improve significantly on the 4th day(P<0.001).T-Bil improved on day 5(P<0.01),and ALT improved significantly on day 6(P<0.001).CRP increased every day up to day 6(P<0.001).In group II,AST and ALT increased after admission,and thereafter CRP increased,then decreased.The frequency of use of aspirin and aspirin doses did not differ significantly in the three groups.Interpretation:Recovery from liver dysfunction occurred in the initial stage of illness in group I-within the period of CRP exacerbation,which is an indicator of systemic inflammation. | Yasuhiko Tomita Takashi Fukaya Yasuko Yamaura Rie Tsujiguchi Haruko Muratani Maki Shimaya | 2019 | Pediatric Investigation2019，3，1： | 3 |
| 2 | Characterization of N-methyl-D-aspartate receptor subunits responsible for postoperative pain 显示文摘 | Nishimura W Muratani T | 2004 | Eur J Phanna- col2004，503，13： | 1 |
| 3 | Colon cacer screening by a new test:a prospective study of asymptomatic population显示文摘 | Samoto K Muratani M Ogawa J | 1993 | Proc AM ASSOC Cancer Res1993，32，： | 1 |
| 4 | In-vitro evaluation of the fourbeta-lactamase inhibitors:BRL42715,clavulanic acid,sulbactam,and tazobactam显示文摘 | Muratani T | 1993 | JAn tim icrob Chem other1993，32，： | 1 |
| 5 | Drug susceptibility of bacteria isolated from pediatric respiratory infections at general practitioners'clinics to pediatric antibiotics显示文摘 | Hirakata Y Komatsu M Muratani T | 2009 | Jpn J Antibiot2009，62，： | 1 |
| 6 | Pituitary Abscess Secondary to isolated Sphenoid Sinusitis显示文摘 | Shono T Nishio S Muratani H | 1999 | Minim Invasive Neurosurg1999，42，4： | 1 |
| 7 | Genetic analysis of faropenem-resistant Enterococcus faecalis in urinary isolates 显示文摘 | Hiraga N Muratani T Naito S | 2008 | Antibiot2008，61，4： | 1 |
| 8 | Clinical effects of 2 days of treatment by fosfomycin calcium for acute uncomplicated cys- titis in women显示文摘 | Matsumoto T Muratani T Nakahama C | 2011 | J Infect Chemother2011，17，： | 1 |
| 9 | In-vitro evaluation of the four beta-lactamase inhibitors:BRL42715,clavulanic acid,sulbactam,and tazobactam显示文摘 | Muratani T Yokota E Nakane T | | 0，，03： | 1 |
| 10 | Solubilization of meso-carbon microbeads by potassium or dibutylzinc-promoted butyla-tion and structural analysis of the butylated products 显示文摘 | Zhang Yan Kidena K Muratani T | 1997 | Energy and Fuels1997，11，2： | 1 |
| 11 | In vitro of T-3761,a new fluoroquinolone显示文摘 | Muratani T Inoue M Mitsuhashi S | 1992 | Antimicrobial Agent and Chemotherapy1992，36，10： | 1 |
| 12 | How the ubiquitin-pmteasome system controls transcription 显示文摘 | Muratani M Tansey WP | 2003 | Nat Bey MoI Cell Biol2003，4，3： | 1 |
| 13 | Contribution of a2-adrenoceptors in caudal ventrolateral medulla to cardiovascular regulation in rat显示文摘 | Sesoko S Muratani H Yamazato M | 1998 | Am J Physiol1998，274，42： | 1 |
| 14 | Office blood pressure variability as a predictor of brain infarction in elderly hypertensive patients显示文摘 | Hata Y Kimura Y Muratani H | 2000 | Hypertens Res2000，23，6： | 1 |
| 15 | Aminoglutethimide effect on circadian rhythms in urinary variables in a patient with idiopathic hyperaldosteronism 显示文摘 | Muratani H Ueno M Kawasaki T | 1985 | Chronobiologia1985，12，1： | 1 |
| 16 | Office blood pressurevariability as a predictor of acute myocardial infarction in elderlypatients receiving antihypertensive therapy显示文摘 | Hata Y Muratani H Kimura Y | 2002 | J Hum Hypertens2002，16，2： | 1 |
| 17 | Three-dimensional CT angiography for the surgical management of the vertebral artery-posterior inferior cerebellar artery aneurysms显示文摘 | P. Huynh-Le T. Matsushima M. Miyazono T. Sayama H. Muratani T. Tashima T. Sasaki | 2004 | Acta Neurochirurgica2004，，4： | 1 |
| 18 | Outbreak of cefozopran (penicillin,oral cephems,and aztreonam)-resistant Neisseria gonorrhoeae in Japan显示文摘 | Muratani T Akasaka S Kobayshi T | 2001 | Antimicrob Agents Chemother2001，45，12： | 1 |
| 19 | Influence of endotracheal tube cuff lubrication on postoperative sore throat and hoarseness显示文摘 | Kori K Muratani T Tatsumi S | 2009 | Masui2009，58，3： | 1 |
| 20 | Increase in pulse pressure relates to diabetes mellitus and low HDL cholesterol,but not to hyperlipidemia in hypertensive patients aged 50 years or older显示文摘 | Miyagi T Muratani H Kimura Y | 2002 | Hypertens Res2002，25，： | 1 |
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