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| 1 | Engineering an enthesis-like graft for rotator cuff repair:An approach to fabricate highly biomimetic scaffold capable of zone-specifically releasing stem cell differentiation inducers显示文摘Rotator cuff(RC)attaches to humerus across a triphasic yet continuous tissue zones(bone-fibrocartilage-tendon),termed“enthesis”.Regrettably,rapid and functional enthesis regeneration is challenging after RC tear.The existing grafts bioengineered for RC repair are insufficient,as they were engineered by a scaffold that did not mimic normal enthesis in morphology,composition,and tensile property,meanwhile cannot simultaneously stimulate the formation of bone-fibrocartilage-tendon tissues.Herein,an optimized decellularization approach based on a vacuum aspiration device(VAD)was developed to fabricate a book-shaped decellularized enthesis matrix(O-BDEM).Then,three recombinant growth factors(CBP-GFs)capable of binding collagen were synthesized by fusing a collagen-binding peptide(CBP)into the N-terminal of BMP-2,TGF-β3,or GDF-7,and zone-specifically tethered to the collagen of O-BDEM to fabricate a novel scaffold(CBP-GFs/O-BDEM)satisfying the above-mentioned requirements.After ensuring the low immunogenicity of CBP-GFs/O-BDEM by a novel single-cell mass cytometry in a mouse model,we interleaved urine-derived stem cell-sheets into this CBP-GFs/O-BDEM to bioengineer an enthesis-like graft.Its high-performance on regenerating enthesis was determined in a canine model.These findings indicate this CBP-GFs/O-BDEM may be an excellent scaffold for constructing enthesis-like graft to patch large/massive RC tears,and provide breakthroughs in fabricating graded interfacial tissue. | Can Chen Qiang Shi Muzhi Li Yang Chen Tao Zhang Yan Xu Yunjie Liao Shulin Ding Zhanwen Wang Xing Li Chunfeng Zhao Lunquan Sun Jianzhong Hu Hongbin Lu | 2022 | Bioactive Materials2022，7，10： | 4 |
| 2 | Cloning and identification of a novel RNF6 transcrip-tional splice variant Spg2 in human development显示文摘RING finger proteins are zinc finger proteins containing the RING motifs. They act mainly as E3 ubiq-uitin ligases, bind the ubiquitin E2 conjugating enzyme and promote degradation of targeted proteins, Many novel genes have been isolated and differentially expressed in human adult and embryo testis by a testis cDNA-array differential display technique. A novel RING finger cDNA is highly expressed in adult testis and at low level in fetal testis. It was named Spg2. It contains a 2055 nucleotide ORF, en-codes a 685-amino-acid RNF6 protein, and has a RING finger in its C terminal. NCBI Blast shows that the gene is located on chromosome 13 and contains five exons. A multiple tissue expression profile also indicates that it is highly expressed in human testis, so we speculate that it may be associated with human spermatogenesis by virtue of the action of its RING domain. | ZHU Li TONG GuoQin CHEN Jie WANG Yun WANG SaiQun ZHAO MuZhi LI JianMin MA JianHua | 2008 | Science China(Life Sciences)2008，51，4： | 3 |
| 3 | Design and analysis of a new high frequency double-servodirect drive rotary valve显示文摘Researchers have investigated direct drivevalve for many years to solve problems, such as fluidforce imbalance and switching frequency. The structure ofthe rotary valve has received considerable research interestbecause of its favorable dynamic properties and simplestructure. This paper studied the high frequency double-servo direct drive rotary valve (DDRV), and proposed anovel structure and drive method satisfying high reversingfrequency and adequate quantity of flow. Servo motors areintegrated into the valve by the innovative structure, whichis designed to equilibrate the unbalanced radial fluid forcewith the symmetric distributed oil ports. Aside from thefast reversing function of the valve, the DDRV presentedhigh performance in linearity of the flow quantity andvalve opening as a result of the fan-shaped flow ports. Inaddition, a computational fluid dynamics (CFD) methodbased on Fluent was conducted to verify the flux regulationeffect of the height change of the adjustable boss. | Muzhi ZHU Shengdun ZHAO Jingxiang LI | 2016 | Frontiers of Mechanical Engineering2016，11，4： | 3 |
| 4 | Effect of Image Noise on the Classification of Skin Lesions Using Deep Convolutional Neural Networks显示文摘Skin lesions are in a category of disease that is both common in humans and a major cause of death.The classification accuracy of skin lesions is a crucial determinant of the success rate of curing lethal diseases.Deep Convolutional Neural Networks(CNNs)are now the most prevalent computer algorithms for the purpose of disease classification.As with all algorithms,CNNs are sensitive to noise from imaging devices,which often contaminates the quality of the images that are fed into them.In this paper,a deep CNN(Inception-v3)is used to study the effect of image noise on the classification of skin lesions.Gaussian noise,impulse noise,and noise made up of a compound of the two are added to an image dataset,namely the Dermofit Image Library from the University of Edinburgh.Evaluations,based on t-distributed Stochastic Neighbor Embedding(t-SNE)visualization,Receiver Operating Characteristic(ROC)analysis,and saliency maps,demonstrate the reliability of the Inception-v3 deep CNN in classifying noisy skin lesion images. | Xiaoyu Fan Muzhi Dai Chenxi Liu Fan Wu Xiangda Yan Ye Feng Yongqiang Feng Baiquan Su | 2020 | Tsinghua Science and Technology2020，25，3： | 2 |
| 5 | Identification oftrace element sources and associated risk assessment invegetable soils of the urban-rural transitional area of Han-gzhou,China显示文摘 | Chen Tao Liu Xingmei Zhu Muzhi | 2008 | Environmental Pollution2008，151，： | 1 |
| 6 | Identification of trace element sources and associated risk assessment in vegetable soils of the urban- rural transitional area of Hangzhou, China显示文摘 | Chen Tao Liu Xingmei Zhu Muzhi | 2008 | Environmental Pollution2008，151，： | 1 |
| 7 | Some Thoughts On Democracy显示文摘In analyzing the question of democracy, we need to concentrate on its essence. It won’t do for us just to look at the form it assumes. The people want democracy because they need to have certain demands met and certain interests realized. They will strive for democracy when they are denied of the right to pursue their demands and interests. It is clear that democracy has always been associated with the people’s demands and interests. The essence of | ZHU MUZHI | 2002 | The Journal of Human Rights2002，1，4： | 1 |
| 8 | Identifica- tion of trace element source and associated risk assessment in vegetable soils of the urban-rural transitional area of Hangzhou, China 显示文摘 | CHEN Tao LIU Xingmei ZHU Muzhi | 2008 | Environ Pollut2008，151，1： | 1 |
| 9 | Identification of trace element sources and associated risk assessment in vegetable soils of the urban-rural transitional area of Hangzhou, China显示文摘 | CHEN Tao LIU Xingmei ZHU Muzhi el al | 2008 | Environmental Pollution2008，151，： | 1 |
| 10 | Identification of trace element sources and associated risk assessment in vegetable soils of the urban–rural transitional area of Hangzhou, China显示文摘 | Tao Chen Xingmei Liu Muzhi Zhu Keli Zhao Jianjun Wu Jianming Xu Panming Huang | 2007 | Environmental Pollution2007，，1： | 1 |
| 11 | Identification of traceelement sources and associated risk assessment in vegetable soils ofthe urbane rural transitional area of Hangzhou,China显示文摘 | CHEN Tao LIU Xingmei ZHU Muzhi | 2008 | EnvironPollut2008，151，1： | 1 |
| 12 | SrAl_(2)O_(4) crystallite embedded inorganic medium with super-long persistent luminescence,thermoluminescence, and photostimulable luminescence for smart optical information storage显示文摘As a leader of long persistent luminescence(LPL) materials, the optical properties of aluminate phosphor have remained unsurpassed for many years. As a powder material, its practical application will always be limited to the field of security signs. In this paper, the SrAl_(2)O_(4)∶Eu^(2+), Dy^(3+)inorganic solid material with comparable LPL properties to powder materials was obtained. The crystallization mechanism and crystallite micro-morphology of inorganic glass materials have been studied, and a new opinion is put forward that the large-size SrAl_(2)O_(4)crystallites in the glass matrix are stacked by rod-shaped crystals arranged in a regular direction. In addition,the SrAl_(2)O_(4)∶Eu^(2+), Dy^(3+)glass obtained cannot only collect high-energy photons but also is sensitive to lowenergy sunlight. The results show that the material exhibits superior performance in LPL, thermoluminescence,and photostimulable luminescence. Based on this property, a new application of this material in the field of information storage was explored. This paper has a certain reference value for the development and application of aluminate LPL materials in the field of smart optical information storage. | Panpan Li Youjie Hua Renguang Ye Muzhi Cai Shiqing Xu Junjie Zhang | 2022 | Photonics Research2022，10，2： | 1 |
| 13 | Effects of trace calcium and strontium on microstructure and properties of Cu-Cr alloys显示文摘Cu-0.57Cr-0.01Ca and Cu-0.58Cr-0.01Sr(wt.%)alloys were fabricated and processed by thermo-mechanical treatment.Their mechanical and electrical properties and microstructure were investigated in detail and compared with those of a Cu-0.57Cr(wt.%)alloy.The results showed that the softening resistance of the Cu-Cr alloy was significantly improved by the additions of Ca and Sr elements.Compared with the Cu-Cr alloy,the deformation microstructure of the Cu-Cr-Ca and Cu-Cr-Sr alloys was more difficult to recrystallize at elevated temperatures,and the Cr precipitates in the Cu-Cr-Ca and Cu-Cr-Sr alloys were smaller in size and had an FCC structure at any given aging state.The high strengths of the Cu-Cr-Ca and Cu-Cr-Sr alloys were mainly attributed to the dislocation strengthening provided by high-density dislocations and the precipitate strengthening provided by fine Cr precipitates.First-principles calculation showed that the segregations of Ca and Sr atoms at interface between Cr precipitates and copper matrix were favorable in energetics.This segregation effectively hindered the growth of Cr precipitates and significantly enhanced the pinning effect on the motion of dislocations and subgrain boundaries,eventually leading to the improvement in the softening resistance of the Cu-Cr alloy. | Muzhi Ma Zhu Xiao Xiangpeng Meng Zhou Li Shen Gong Jie Dai Hongyun Jiang Yanbin Jiang Qian Lei Haigen Wei | 2022 | Journal of Materials Science & Technology2022，，17： | 1 |
| 14 | High-performance all-solution-processed inverted quantum dot light-emitting diodes enabled by water treatment显示文摘All-solution-processed inverted quantum dot(QD)light-emitting diodes(QLEDs)with transparent bottom cathodes can be directly connected to the n-type thin-film transistors,offering a feasible solution for low-cost active matrix-driven QD displays.However,the subsequent solution-deposition of the hole-transporting layer destroys the underneath QD films,resulting in largely deteriorated device performance.Various strategies have been implemented to prevent QD film from dissolution,but all at a heavy cost of device performance suffering from either reduced efficiency or increased driving voltage.Here,a facile and effective water-treatment approach for QD film to fabricate inverted QLEDs through all solution processing is reported.The water treatment substitutes the long-chain oleate ligands with hydroxyl groups,resulting in significantly improved non-polar solvent resistance of the QD films.Importantly,the QD films reserve their excellent photoluminescence efficiency after water treatment.With the water-treated QD film as the emissive layer,all-solution-processed inverted red QLED with a peak external quantum efficiency of 19.6%,a turn-on voltage of 1.8 V,and a T50 operational lifetime of 150,000 h at 100 cd·m^(-2) was achieved.Furthermore,efficient and low-voltage-driven green and blue QLEDs can also be prepared with this method.This work provides a feasible strategy for the fabrication of high-performance all-solution-processed inverted QLEDs,paving the way toward achieving QLEDs by all ink-jet printing. | Qianqing Hu Junjie Si Desui Chen Xiaoming Hao Rui Xu Yihang Du Zhuopeng Du Xinquan Gong Hong Zhao Peiqing Cai Qi Ai Xin Yao Yu Yan Zenan Zhang Muzhi Cai Wei Liu Yongyin Kang Zugang Liu | 2023 | Nano Research2023，16，7： | 0 |
| 15 | REFUTING SO-CALLED DESTRUCTION OF TIBETAN CULTURE显示文摘The culture of every nation is bound to develop and make progress along with social development and progress. This is true, too, of Tibetan culture. As China furthers the cause of building socialism with Chinese characteristics, a new progressive culture will keep replacing an old and backward culture. Any attempt to impede and reverse such progress constitutes real destruction of a culture. Such an attempt can never succeed. Nor will the attempt of the Dalai Lama. | ZHU MUZHI | 2003 | The Journal of Human Rights2003，2，1： | 0 |
| 16 | Effect of Ti additions on microstructure and mechanical properties of Cu-Cr-Zr alloy显示文摘Ti additions in Cu–Cr–Zr alloys are useful for achieving high mechanical properties.In this work,the influence of Ti contents(0.25 wt%,0.6 wt%,and 1.02 wt%)on the microstructure,mechanical,and electrical properties of Cu–Cr–Zr alloys has been investigated experimentally,along with thermodynamic and kinetic calculations.The electrical conductivity decreased but the hardness/strength increased with increasing Ti content.The lower electrical conductivity is due to increased electron scattering through the solution of more Ti atoms in the Cu matrix.As for the higher hardness/strength,it is mainly owing to higher dislocation density and finer FCC-Cr precipitates.Furthermore,a model considering the size distributions of precipitates is adopted to calculate precipitation strengthening quantitatively.The calculated yield strengths are consistent with the experimental ones for the alloys.The thermodynamic and kinetic calculations reveal that increasing Ti content can facilitate the nucleation of FCC-Cr but enhance its activation energy,hence hindering the growth process.The present work study can provide an effective strategy for producing copper alloys with expected performance. | Chenying Shi Muzhi Ma Biaobiao Yang Yuling Liu Yushen Huang Yong Du | 2023 | Journal of Materials Science & Technology2023，，32： | 0 |
| 17 | Novel ultra-wideband fluorescence material:Defect state control based on nickel-doped semiconductor QDs embedded in inorganic glasses显示文摘In recent years,the development of an environmentally friendly quantum dots(QDs)embedded luminous solid by a simple method has attracted considerable attention.In this study,semiconductor ZnS QDs were successfully prepared in an inorganic matrix of amorphous glass,which yielded beneficial broadband emission in the long-wavelength region of the visible range.The strong red emission belonged to the defect state energy level of the ZnS QDs,which could be enhanced by incorporation of nickel ions into the fixed matrix to regulate the defects state.The novel material had a small self-absorption,wide excitation and emission ranges,and thus potential applications in light-conversion devices,luminescent solar concentrators,and solar cell cover glasses. | Zheng Wang Feifei Huang Muzhi Cai Xianghua Zhang Degang Deng Shiqing Xu | 2023 | Journal of Materiomics2023，9，2： | 0 |
| 18 | Pursuing Human Rights——A Fair Go for All显示文摘The theme of this human rights conference is 'Human Rights: A Fair Go For All.' It’s true that all people wish to enjoy human rights, especially those who lack or are deprived of human rights. The Chinese peopie used to have no human rights at all. They paid a most terrifying price through bloodshed and sacrifices to win their rights today. Therefore, the Chinese people attach great importance to and very much treasure human rights, and they also harbor great sympathy for those who still lack human rights. In today’s world, | ZHU MUZHI | 2002 | The Journal of Human Rights2002，1，1： | 0 |
| 19 | Stability and Democracy显示文摘Stability is of extreme importance to China which is focusing on economic development, reform and opening up. Without stability, there is no way of carrying out reform and opening up, let alone economic development. Just as Deng Xiaoping said, 'Without a stable environment, nothing could be accomplished.' Stability has ensured a sustainable and rapid development of China in these years. Why can China maintain stability? Some people in the West accuse China of autocracy, saying that the stress of stability is nothing but a pretext of suppressing | ZHU MUZHI The author is Honorary President of the China Society for Human Rights Studies. | 2004 | The Journal of Human Rights2004，3，1： | 0 |
| 20 | 一生一歌乌镇木心美术馆显示文摘浙江乌镇东栅是著名旅美文学家、画家木心的故乡.为了纪念这位文化名人,在2014年时,当地就将乌镇的东栅财神湾168号“晚晴小筑”辟为的木心故居纪念馆;而此次位于西栅的木心美术馆,文化乌镇股份有限公司更是请到美国OLI建筑设计事务所设计督造,两位合伙人冈本博与林兵,历时4年,精心打造,美术馆于2015年11月正式开馆. | 时颜(整理) 冈本博 AIA 林兵 Fabian Servagnat Steve Hopkins AIA Po Chen Dongshin Lee Muzhi Chen Michael Zhao Grace Kim Michael Pryor S.J.Kwon Remi Bun Jerry Lu Shen Zhonghai(摄影) 无 | 2016 | 室内设计与装修2016，0，7： | 0 |
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