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| 1 | Rat hair follicle stem cells differentiate and promote recovery following spinal cord injury显示文摘Emerging studies of treating spinal cord injury(SCI)with adult stem cells led us to evaluate the effects of transplantation of hair follicle stem cells in rats with a compression-induced spinal cord lesion.Here,we proposed a hypothesis that rat hair follicle stem cell transplantation can promote the recovery of injured spinal cord.Compression-induced spinal cord injury was induced in Wistar rats in this study.The bulge area of the rat vibrissa follicles was isolated,cultivated and characterized with nestin as a stem cell marker.5-Bromo-2′-deoxyuridine(BrdU)labeled bulge stem cells were transplanted into rats with spinal cord injury.Immunohistochemical staining results showed that some of the grafted cells could survive and differentiate into oligodendrocytes(receptor-interacting protein positive cells)and neuronal-like cells(βIII-tubulin positive cells)at 3 weeks after transplantation.In addition,recovery of hind limb locomotor function in spinal cord injury rats at 8 weeks following cell transplantation was assessed using the Basso,Beattie and Bresnahan(BBB)locomotor rating scale.The results demonstrate that the grafted hair follicle stem cells can survive for a long time period in vivo and differentiate into neuronal-and glial-like cells.These results suggest that hair follicle stem cells can promote the recovery of spinal cord injury. | Nowruz Najafzadeh Maliheh Nobakht Bagher Pourheydar Mohammad Ghasem Golmohammadi | 2013 | Neural Regeneration Research2013，8，36： | 6 |
| 2 | Hair follicle stem cells: In vitro and in vivo neural differentiation显示文摘Hair follicle stem cells(HFSCs) normally give rise to keratinocytes, sebocytes, and transient amplifying progenitor cells. Along with the capacity to proliferate rapidly, HFSCs provide the basis for establishing a putative source of stem cells for cell therapy. HFSCs are multipotent stem cells originating from the bulge area. The importance of these cells arises from two important characteristics, distinguishing them from all other adult stem cells. First, they are accessible and proliferate for long periods. Second, they are multipotent, possessing the ability to differentiate into mesodermal and ectodermal cell types. In addition to a developmental capacity in vitro, HFSCs display an ability to form differentiated cells in vivo. During the last two decades, numerous studies have led to the development of an appropriate culture condition for producing various cell lineages from HFSCs. Therefore, these stem cells are considered as a novel source for cell therapy of a broad spectrum of neurodegenerative disorders. This review presents the current status of human, rat, and mouse HFSCs from both the cellular and molecular biology and cell therapy perspectives. The first section of this review highlights the importance of HFSCs and in vitro differentiation, while the final section emphasizes the significance of cell differentiation in vivo. | Nowruz Najafzadeh Banafshe Esmaeilzade Maryam Dastan Imcheh | 2015 | World Journal of Stem Cells2015，7，5： | 3 |
| 3 | Molecular identification of Penicillium marneffei using rolling circle amplification 显示文摘 | Sun J Najafzadeh MJ Zhang J | 2011 | Mycoses2011，54，6： | 1 |
| 4 | Molecular epidemiology of Fonsecaea species 显示文摘 | Najafzadeh MJ Sun J Vicente VA | 2011 | Emerg Infect Dis2011，17，3： | 1 |
| 5 | The clinical spectrum of Exophiala jeanselmei, with a case report and in vitro antifungal susceptibility of the species显示文摘 | Badali H Najafzadeh MJ van Esbroeck M | 2010 | Med Mycol2010，48，2： | 1 |
| 6 | First report of rhinosinusitis caused by Neoscytalidium dimidiatum in Iran 显示文摘 | Bakhshizadeh M Hashemian HR Najafzadeh MJ | 2014 | J Med Microbiol2014，63，7： | 1 |
| 7 | Future impact of various inter- ventions on the burden of COPD in canada: A Dynamic Population Model 显示文摘 | Najafzadeh M Marra CA Lynd LD | 2012 | PLoS 0ne2012，7，46： | 1 |
| 8 | Using the incre- mental net benefit framework for quantitative benefit-risk a- nalysis in regulatory decision making-a case study of Alps- erton in irritable bowel syndrome 显示文摘 | Lynd LD Najafzadeh M Colley L | 2010 | Value in Health2010，13，4： | 1 |
| 9 | The clinical spectrum of Exophiala jeanselmei, with a case report and in vitro antifungal susceptibility of the species 显示文摘 | Badali H Najafzadeh MJ Van Esbroeck M | 2010 | Med Mycol2010，48，2： | 1 |
| 10 | Chemical and microbial properties of mahyaveh, a traditional Iranian fish sauce 显示文摘 | Zarei M Najafzadeh H Eskandari M H | 2012 | Food Control2012，23，2： | 1 |
| 11 | Low-dose all-trans retinoic acid enhances cytotoxicity of cisplatin and 5-fluorouracil on CD44+ cancer stem cells显示文摘 | Najafzadeh N Mazani M Abbasi A | 2015 | Biomed Pharmacother2015，74，： | 1 |
| 12 | Rapid screening for human-pathogenic Mueorales using roiling circle amplification 显示文摘 | Dolatabadi S Najafzadeh MJ de Hoog GS | 2014 | Mycoses2014，57，3： | 1 |
| 13 | Molecular epidemiology of F onsecaea species 显示文摘 | Najafzadeh MJ Sun J Vicente VA | 2011 | Emerg Infect Dis2011，17，3： | 1 |
| 14 | Molecular epidemiology of Fonseeaea species 显示文摘 | Najafzadeh MJ Sun J Vicente VA | 2011 | Emerg Infect Dis2011，17，3： | 1 |
| 15 | Molecular identification of Penicillium marneffei using rolling circle amplification显示文摘 | Sun J Najafzadeh M J Zhang J | 2011 | Mycoses2011，54，6： | 1 |
| 16 | Bsm:broadcasting of safety message in vehicular ad hoc networks显示文摘 | NAJAFZADEH S ITHNIN N RAZAK S A | 2014 | Arabian Journal for Science and Engineering2014，39，2： | 1 |
| 17 | Low-dose all-trans retinoic acid enhances cytotoxicity of cisplatin and 5-fluorouracil on CD44(+) cancer stem cells显示文摘 | Najafzadeh N Mazani M Abbasi A | 2015 | Biomed Pharmacother2015，74，： | 1 |
| 18 | Flavonoids inhibit the genotoxicity of hydrogen peroxide (H(2)O(2显示文摘 | NAJAFZADEH M REYNOLDS PD BAUMGARTNER A | | 0，，5： | 1 |
| 19 | Melanization of a meristematic mutant of Fonsecaea monophora increases tolerance to stress factors while no effects on antifungal susceptibility显示文摘 | Sun J Zhang J Najafzadeh MJ | 2011 | Mycopathologia2011，172，5： | 1 |
| 20 | Successful treatment of chromoblastomycosis of 36 years duration caused by Fonsecaea monophora显示文摘 | Najafzadeh MJ Rezusta A Cameo MI | | 0，，02： | 1 |
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