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| 1 | Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation显示文摘 | Theise ND Badve S Saxena R | | 0，，： | 5 |
| 2 | Impact of proteolytic enzymes in colorectal cancer development and progression显示文摘Tumor invasion and metastasis is a highly complicated, multi-step phenomenon. In the complex event of tumor progression, tumor cells interact with basement membrane and extracellular matrix components. Proteolytic enzymes(proteinases) are involved in the degradation of extracellular matrix, but also in cancer invasion and metastasis. The four categories of proteinases(cysteine-, serine-, aspartic-, and metalloproteinases) are named and classified according to the essential catalytic component in their active site. We and others have shown that proteolytic enzymes play a major role not only in colorectal cancer(CRC) invasion and metastasis, but also in malignant transformation of precancerous lesions into cancer. Tissue and serumplasma antigen concentrations of proteinases might be of great value in identifying patients with poor prognosis in CRC. Our results, in concordance with othersindicate the potential tumor marker impact of proteinases for the early diagnosis of CRC. In addition, proteinases may also serve as potential target molecules for therapeutic agents. | László Herszényi Loránd Barabás István Hritz Gábor István Zsolt Tulassay | 2014 | World Journal of Gastroenterology2014，20，37： | 3 |
| 3 | Relationship between metabolic syndrome and erectile dysfunction显示文摘Aim: To determine the relationship between metabolic syndrome (MS) and erectile dysfunction (ED) and to see which risk factors correlated the best with ED. Methods: Seventy-nine cardiology clinic outpatients with coronary artery disease (CAD) and lipid metabolism disorder were recruited. They were categorized as having MS,hypertension (blood pressure greater than 130/85 mmHg) and dyslipidemia. ED was classified based on International Index of Erectile Function scores. Patients were grouped into quartiles based on body mass index (BMI). Chi-square,Pearson's correlation and regression tests were used for statistical analysis. Results: The mean age of the patients was 56.6 years. ED was diagnosed in 59 (74.7 %) of the 79 patients. In the 38 patients with MS, all had ED. ED was not significantly correlated with cholesterol levels (P>0.05), but was found often in patients who had both hypercholesterolemia and HT (P<0.01). Nineteen(76 %) of the 25 patients who had dyslipidemia had ED. However, ED wasnot significantly correlated with dyslipidemia (P>0.05). Tweenty-two of the 23 patients who had BMI greater than30 had ED, which was significantly more prevalent than that in those who had normal BMI (P<0.01). ED was seen in 38 of 53 smoker patients. Although ED was more prevalent in cigarette smokers, it was not significantly different from non-smokers (P>0.5). Conclusion: ED is present in a high percentage of patients with MS. Among multiple risk factors for ED, MS correlates the most highly. The next most important risk group is the patients with hypertension +hypercholestrolemia and obesity (BMI>30). (Asian JAndrol 2004 Dec; 6: 355-358) | M.I.Gündüz B.H.Gümüs C.Sekuri | 2004 | Asian Journal of Andrology2004，6，4： | 2 |
| 4 | Derivation of hepatocytes from bone marrow cells in mice after radiation- induced myeloablation显示文摘 | Theise ND Badve S Saxena R | 2000 | Hepatology2000，31，1： | 1 |
| 5 | Loss of p53 funtion in uterine papillary serous carcinoma显示文摘 | Kovalev S Marchenko ND Gugliotta BG | 1998 | Hum pahthol1998，29，6： | 1 |
| 6 | Perfusion MRI of brain tumours: a comparative study of pseudo-continuous arterial spin labelling and dynamic susceptibility contrast imaging显示文摘 | Hanna J?rnum Elena G. Steffensen Linda Knutsson Ernst-Torben Fründ Carsten Wiberg Simonsen S?ren Lundbye-Christensen Ajit Shankaranarayanan David C. Alsop Finn Taageh?j Jensen Elna-Marie Larsson | 2010 | Neuroradiology2010，，4： | 1 |
| 7 | Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation 显示文摘 | Theise ND Badve S Saxena R | 2000 | Hepatology2000，31，1： | 1 |
| 8 | Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults 显示文摘 | Malik S Wong ND Franklin SS | 2004 | Circulation2004，110，10： | 1 |
| 9 | Empathy training and the regulation of aggression显示文摘 | Feshbach ND Feshbach S | 1982 | Potentialities and Limitations Acad Psychol Bull1982，4，： | 1 |
| 10 | Empathy training and the regulation of aggression:ntialities and limitations显示文摘 | Feshbach ND Feshbach S | 1982 | Acad Psychol Bull1982，4，： | 1 |
| 11 | Gene discovery in bladder cancer progression using cDNA microarrays显示文摘 | SANCHEZ CM ND S JJ L | 2003 | Am Pathol2003，163，： | 1 |
| 12 | Impact of themetabolic syndrome on mortality from coronary heart disease,cardiovascular disease,and all causes in United States adults显示文摘 | MALIK S WONG ND FRANKLIN SS | 2004 | Circulation2004，110，： | 1 |
| 13 | Reduced plaque formation by the chloromethyl analogue of Vitamin C显示文摘 | Turesky S Gilmore ND Glickman I | 1970 | J Periodontol1970，41，： | 1 |
| 14 | Vision disturbances after operative hysteroscopy 显示文摘 | Motashaw ND Dave S | 1999 | J Am Assoc Gynecol Laparosc1999，6，2： | 1 |
| 15 | Genistein induced upregulation of p21ASF1 downregulation of cyclin B,and induction of apoptosis in prostate cancer cells显示文摘 | Joanne ND Brahmchetna S Mahbubur B | 1998 | Nutr Cancer1998，32，3： | 1 |
| 16 | Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation显示文摘 | Theisc ND Badve S Saxcna R | 2000 | Hepatology2000，31，： | 1 |
| 17 | Functional resting-state networks are differentially affected in schizophrenia显示文摘 | Woodward ND Rogers B Heckers S | 2011 | Schizophr Res2011，130，13： | 1 |
| 18 | Asymptomatic DNAemia heralds CMV-associated NEC: ease report, review, and rationale for preemption显示文摘 | Tengsupakul S Birge ND Bendel CM | 2013 | Pediatrics2013，132，： | 1 |
| 19 | ATF3 is a novel regulator of mouse neutrophil migration显示文摘 | Boespflug ND Kumar S McAlees JW | 2014 | Blood2014，123，13： | 1 |
| 20 | Overexpression of the wild type p73 gene in breast cancer tissues and cell lines显示文摘 | Zaika AI Kovalev S Marohenko ND | 1999 | Cancer Res1999，59，13： | 1 |
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